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The right to be forgotten and outstanding balance insurance: a proposition for type 1 diabetes [printed text] / Ans Van Ginckel , Author ; Christophe de Meester , Author ; Imgard Vinck , Author ; Kelly Sabbe, Author ; Julien Antunes Mendes, Author ; Pierre-Alexandre Louis, Author ; Diego Castanares-Zapatero , Author ; Marijke Eyssen , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2024 . - 164 p. : ill., ; A4. - (KCE Reports. Right to be forgotten; 387C) .
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Languages : English (eng)

Descriptors:	Classification WK 810 Diabetes mellitus Indexation 2020-82 ; Diabetes Mellitus ; Insurance ; Mortality ; R387 ; Survival Analysis
Contents note:	LIST OF FIGURES 6 -- LIST OF TABLES 8 -- LIST OF ABBREVIATIONS 11 -- SCIENTIFIC REPORT 13 -- GENERAL INTRODUCTION 13 -- 1 OUTLINE OF THIS REPORT 13 -- 2 CONTEXT AND SCOPE 14 -- 2.1 THE RIGHT TO BE FORGOTTEN IN BELGIUM 14 -- 2.2 INTERNATIONAL CONTEXT 15 -- 2.2.1 France 15 -- 2.2.2 Portugal 16 -- 2.3 THE TASK OF THE KCE 16 -- 2.4 RATIONALE FOR TYPE 1 DIABETES AS THE FIRST STUDY TOPIC ON CHRONIC DISEASES 19 -- 2.4.1 Stakeholder interest and policy relevance 19 -- 2.4.2 Update and elaboration of KCE report 314 19 -- 2.4.3 Feasibility and novelty 20 -- 3 TYPE 1 DIABETES 20 -- 3.1 PATHOGENESIS 20 -- 3.2 EPIDEMIOLOGY 21 -- 3.2.1 Prevalence and incidence 21 -- 3.2.2 Excess mortality and risk factors 22 -- 3.3 MAIN PRINCIPLES AND RECENT ADVANCES OF CLINICAL MANAGEMENT 26 -- 3.4 ORGANISATION AND QUALITY OF CARE IN BELGIUM 27 -- 4 RESEARCH SCOPE, OBJECTIVES AND QUESTIONS 31 -- 4.1 TARGET AUDIENCE 31 -- 4.2 RESEARCH OBJECTIVES 31 -- 4.3 RESEARCH QUESTIONS 32 -- PART I: MEDICAL AND EPIDEMIOLOGICAL APPROACH 35 -- 5 SYSTEMATIC LITERATURE REVIEW AND META-ANALYSIS 35 -- 5.1 METHODS 35 -- 5.1.1 Research question and selection criteria 35 -- 5.1.2 Search strategy 36 -- 5.1.3 Study selection and data extraction 36 -- 5.1.4 Within-study methodological quality 37 -- 5.1.5 Data synthesis 37 -- 5.2 RESULTS 40 -- 5.2.1 Study selection 40 -- 5.2.2 Characteristics of included studies 40 -- 5.2.3 Results of data synthesis 41 -- 5.3 KEY POINTS 53 -- 6 POPULATION-BASED STUDY USING NATIONAL ROUTINELY COLLECTED HEALTH DATA 54 -- 6.1 PREPARATORY PHASE: STAKEHOLDER OR EXPERT CONSULTATION AND THE QUEST FOR DATA 54 -- 6.2 DATA SOURCES: DATA SELECTION AND VARIABLE DEFINITIONS 55 -- 6.2.1 Administrative health insurance data from the Intermutualistic Agency 55 -- 6.2.2 Selection of Type 1 Diabetes patients 55 -- 6.2.3 Exclusion of patient groups other than Type 1 Diabetes 59 -- 6.2.4 Definition of complications and comorbidities 62 -- 6.2.5 Vital status 63 -- 6.2.6 Reference population 63 -- 6.3 STATISTICAL ANALYSES 64 -- 6.3.1 Period life table approach 64 -- 6.3.2 Prospective lifetable approach 65 -- 6.4 RESULTS 70 -- 6.4.1 Characteristics of the study population: main demographics and disease characteristics 70 -- 6.4.2 Period life table calculations 75 -- 6.4.3 Prospective life table estimations 88 -- 6.5 KEY POINTS 88 -- PART II: INSURANCE-TECHNICAL APPROACH 89 -- 7 CONTEXT 89 -- 8 MORTGAGE 90 -- 8.1 TYPES OF MORTGAGES 90 -- 8.2 MATHEMATICAL FORMULATION 91 -- 9 OUTSTANDING BALANCE INSURANCE PRICING 94 -- 9.1 NOTATIONS 94 -- 9.2 PRICING 94 -- 10 SPECIFIC LIFE TABLES FOR TYPE 1 DIABETES POPULATION 96 -- 10.1 VARIABLES SELECTION 97 -- 10.2 DIABETES DURATION 98 -- 10.3 RAW DATA ANALYSIS 102 -- 10.4 ADVERSE SELECTION ANALYSIS 106 -- 10.5 EXCESS PREMIUM 110 -- 10.5.1 Computation 110 -- 10.5.2 Proposed excess premiums 115 -- 10.6 SENSITIVITY ANALYSIS 123 -- 10.7 CONSIDERATION OF TRANSITIONS BETWEEN STATES 123 -- 10.7.1 Calibration with individual paths 124 -- 10.7.2 Experts opinion 125 -- 10.7.3 Simplified model 125 -- 10.7.4 Computation of the excess premiums 127 -- 10.7.5 Conclusion 130 -- 11 CONCLUSION 131 -- GENERAL DISCUSSION AND CONCLUSION 132 -- 12 DISCUSSION 132 -- 12.1 METHODOLOGICAL CONSIDERATIONS 132 -- 12.1.1 Systematic literature review and meta-analysis 132 -- 12.1.2 Population-based study using routinely collected administrative Belgian health data 133 -- 12.2 INTERPRETATION OF THE FINDINGS IN VIEW OF THE LITERATURE AND NATIONAL CONTEXT 141 -- 12.2.1 Cause of death 141 -- 12.2.2 Complications 142 -- 12.2.3 Comparison with published data from other countries 142 -- 13 CONCLUSION 143 -- 13.1 SUMMARY OF THE KEY FINDINGS 143 -- 13.2 SOCIETAL CONTEXT 143 -- 13.3 PROPOSITION FOR THE LEGISLATIVE REFERENCE TABLES (ANNEX 2) 144 -- REFERENCES 149
Link for e-copy:	https://doi.org/10.57598/R387C
Format of e-copy:	PDF
Record link:	https://kce.docressources.info/index.php?lvl=notice_display&id=5036