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Autologous breast reconstruction techniques after mammary resection / Sophie Gerkens / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2015)  

Autologous breast reconstruction techniques after mammary resection : time measurements for a potential reevaluation of the surgeon fee [printed text] / Sophie Gerkens , Author ; Stefaan Van de Sande , Author ; Roos Leroy , Author ; Anne-Sophie Mertens, Author ; Jonathan Schreiber, Author ; Dries Van Halewyck, Author ; Jan Bellaert, Author ; Hans Van Brabandt , Author ; Nathalie Swartenbroekx, Author ; Caroline Obyn, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2015 . - 102 p. : ill., ; A4. - (KCE Reports. Health Technology Assessment (HTA); 251) . ISSN : D/2015/10/273/77 : € 0,00 Study 2014-25_HTA_Cost_breast_reconstruction Languages : English (eng) Descriptors: Classification W 74 Medical economics. Health care costs (General) Indexation 2014-25 ; Costs and Cost Analysis ; Documents related to KCE studies ; Hospital Costs ; Mammaplasty ; Operative Time ; R251 ; Reimbursement Mechanisms ; Surgical Flaps Contents note: SCIENTIFIC REPORT .9 -- 1 INTRODUCTION 9 -- 1.1 BACKGROUND AND OBJECTIVES 9 -- 1.2 RESEARCH QUESTIONS 9 -- 1.3 DESCRIPTION OF AUTOLOGOUS BREAST RECONSTRUCTION INTERVENTIONS .10 -- 1.3.1 The primary reconstruction or the flap transfer .10 -- 1.3.2 Secondary interventions 14 -- 2 THE CLINICAL EFFECTIVENESS AND SAFETY OF AUTOLOGOUS BREAST RECONSTRUCTION .15 -- 2.1 INTRODUCTION .15 -- 2.2 METHODS 15 -- 2.2.1 Literature search 15 -- 2.2.2 Quality appraisal and data extraction .16 -- 2.3 RESULTS 16 -- 2.4 GENERAL CONCLUSIONS 24 -- 3 BELGIAN PRACTICE: ANALYSES OF BELGIAN HOSPITAL ADMINISTRATIVE DATA 25 -- 3.1 INTRODUCTION .25 -- 3.1.1 Main characteristics of the data sources 25 -- 3.1.2 Cross-sectional data window .26 -- 3.2 METHODS 26 -- 3.2.1 Research questions 26 -- 3.2.2 Target interventions 27 -- 3.2.3 Selection criteria for data extractions .27 -- 3.2.4 Data extraction, transformation and loading (ETL) .27 -- 3.2.5 Checking exhaustiveness of data extraction 29 -- 3.2.6 Check marking codes and stays for breast cancer .29 -- 3.2.7 Research focus tables 29 -- 3.2.8 Grouping interventions and complications 30 -- 3.2.9 Investigating complications in administrative hospital data 31 -- 3.2.10 investigating intervention lead times 32 -- 3.2.11 Calculating fractions and ratios .32 -- 3.2.12 Health insurance costs calculations 33 -- 3.3 RESULTS 34 -- 3.3.1 General results for index interventions .34 -- 3.3.2 Complication rates 40 -- 3.3.3 Intervention lead times 44 -- 3.3.4 Fractions & ratios .45 -- 3.3.5 Health insurance costs 47 -- 3.4 LIMITATIONS AND MAIN FIGURES 51 -- 4 TIME MEASUREMENTS AND VALUATION SCENARIOS FOR THE “SURGEON COST” .53 -- 4.1 INTRODUCTION .53 -- 4.2 SCOPE OF THE STUDY.53 -- 4.2.1 Perspective .53 -- 4.2.2 Treatment considered: the full autologous breast reconstruction episode with flap 53 -- 4.3 TIME DRIVEN COSTING METHODOLOGY 54 -- 4.4 RECRUITMENT AND SELECTION OF THE SURGEON TEAMS 54 -- 4.4.1 Recruitment .54 -- 4.4.2 Candidates 54 -- 4.4.3 Selection 54 -- 4.4.4 Pilot teams 55 -- 4.4.5 Presentation of results 55 -- 4.5 CONSIDERED INTERVENTIONS .55 -- 4.6 THE LIST OF ACTIVITIES RELATED TO THE INTERVENTIONS 58 -- 4.6.1 Activities for the flap transfer 59 -- 4.6.2 Secondary interventions 60 -- 4.6.3 Re-interventions for complications 62 -- 4.7 CONSIDERED RESOURCES 63 -- 4.8 UNIT COSTS FOR EACH RESOURCE AND COST DRIVERS .64 -- 4.8.1 Unit cost for the work done by plastic surgeons and other resources borne by plastic surgeons 64 -- 4.8.2 The work of the surgeons-in-training .68 -- 4.8.3 The work of the tattoo nurse 69 -- 4.8.4 The work of other medical profiles 69 -- 4.8.5 Cost drivers .69 -- 4.9 DATA COLLECTION PLAN AND TEMPLATES .71 -- 4.10 DATA OVERVIEW AND DATA VALIDATION 72 -- 4.11 RESULTS 74 -- 4.11.1 Time results .74 -- 4.11.2 Cost results .83 -- 4.12 SUMMARY OF MAIN FIGURES AND HANDLING OF UNCERTAINTY 93 -- 4.12.1 Constant duration per technique for start and stop activities .93 -- 4.12.2 Variability in intervention duration and man-hours 93 -- 4.13 STUDY LIMITATIONS 97 -- 5 DISCUSSION AND CONCLUSION 98 -- REFERENCES 101 Link for e-copy: https://doi.org/10.57598/R251C Format of e-copy: PDF (1,56 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3628

Autologous breast reconstruction techniques after mammary resection / Sophie Gerkens / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2015)  

Autologous breast reconstruction techniques after mammary resection : time measurements for a potential reevaluation of the surgeon fee - Supplement [printed text] / Sophie Gerkens , Author ; Stefaan Van de Sande , Author ; Roos Leroy , Author ; Anne-Sophie Mertens, Author ; Jonathan Schreiber, Author ; Dries Van Halewyck, Author ; Jan Bellaert, Author ; Hans Van Brabandt , Author ; Nathalie Swartenbroekx, Author ; Caroline Obyn, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2015 . - 85 p. : ill., ; A4. - (KCE Reports. Health Technology Assessment (HTA); 251S) . ISSN : D/2015/10.273/78 : € 0,00 Study 2014-25_HTA_Cost_breast_reconstruction Languages : English (eng) Descriptors: Classification W 74 Medical economics. Health care costs (General) Indexation 2014-25 ; Costs and Cost Analysis ; Documents related to KCE studies ; Hospital Costs ; Mammaplasty ; Operative Time ; R251 ; Reimbursement Mechanisms ; Surgical Flaps Contents note: APPENDICES 4 -- 1 CLINICAL LITERATURE REVIEW 4 -- 1.1 SEARCH STRATEGIES - ELECTRONIC REFERENCE DATABASES: MEDLINE (THROUGH OVID), EMBASE AND THE COCHRANE LIBRARY 4 -- 1.2 STUDY SELECTION AND QUALITY APPRAISAL 10 -- 1.2.1 Flow chart for selection procedure 10 -- 1.2.2 Study selection 11 -- 1.3 QUALITY APPRAISAL OF INCLUDED SYSTEMATIC REVIEWS 13 -- 1.4 EVIDENCE TABLES OF INCLUDED SYSTEMATIC REVIEWS 15 -- 1.4.1 Research question 1: In women who underwent a mastectomy, what is the clinical effectiveness in terms of quality of life in those women who had an autologous breast reconstruction, compared with women who had a breast reconstruction with implants, or a mastectomy without reconstruction? 15 -- 1.4.2 Research question 2: What are the adverse outcomes associated with autologous breast reconstruction? 21 -- 1.4.3 Research question 3: What is the impact of radiotherapy on an autologous breast reconstruction? 27 -- 2 NATIONAL HOSPITAL STAYS DATABASE (NHDB) 34 -- 3 ICD-9-CM PROCEDURE CODES FOR MAMMARY INTERVENTIONS (VERSION DATE: 2015-05-29) 37 -- 4 NIHDI BILLING CODES FOR MAMMARY INTERVENTIONS (VERSION DATE: 2015-05-29) 45 -- 5 – ICD-9-CM DIAGNOSES FOR MAMMARY INTERVENTIONS (VERSION DATE: 2015-05-29) 58 -- 6 INCLUSION-EXCLUSION CRITERIA FOR STAYS AND PATIENTS 69 -- 7 FLAGGING CODES AND STAYS FOR BREAST CANCER INVOLVEMENT 70 -- 8 EXHAUSTIVENESS WITH EXTRACTION-INCLUSION-EXCLUSION 75 -- 8.1 INTERVENTIONS IN HBD 75 -- 8.2 INTERVENTIONS IN MCD 76 -- 8.3 APR-DRG LEVEL 78 -- 9 GROUPING INTERVENTIONS AND COMPLICATIONS 79 -- 10 LEAD TIME AND RATIO CALCULATIONS WITH CENSORED DATA 82 -- 10.1 INTERVENTION LEAD TIMES 82 -- 10.2 NUMERATORS & DENOMINATORS 82 -- 10.3 LEAD TIMES STATISTICS 83 -- 10.4 FRACTIONS AND RATIOS 83 -- REFERENCES 85 Link for e-copy: https://doi.org/10.57598/R251S Format of e-copy: PDF (716 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3629

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Autologous breast reconstruction techniques after mammary resection / Sophie Gerkens / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2015)  

Autologous breast reconstruction techniques after mammary resection : time measurements for a potential reevaluation of the surgeon fee - synthesis [printed text] / Sophie Gerkens , Author ; Stefaan Van de Sande , Author ; Roos Leroy , Author ; Anne-Sophie Mertens, Author ; Jonathan Schreiber, Author ; Dries Van Halewyck, Author ; Jan Bellaert, Author ; Hans Van Brabandt , Author ; Nathalie Swartenbroekx, Author ; Caroline Obyn, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2015 . - 30 p. : ill., ; A4. - (KCE Reports. Health Technology Assessment (HTA); 251Cs) . ISSN : D/2015/10.273/76 : € 0,00 Study 2014-25_HTA_Cost_breast_reconstruction Languages : English (eng) Descriptors: Classification W 74 Medical economics. Health care costs (General) Indexation 2014-25 ; Costs and Cost Analysis ; Documents related to KCE studies ; Hospital Costs ; Mammaplasty ; Operative Time ; R251 ; Reimbursement Mechanisms ; Surgical Flaps Link for e-copy: https://doi.org/10.57598/R251CS Format of e-copy: PDF (494 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3741

Barrières en drijfveren voor de opname van biosimilaire geneesmiddelen in België / Isabelle Lepage-Nefkens / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)  

Barrières en drijfveren voor de opname van biosimilaire geneesmiddelen in België : - Synthese [printed text] / Isabelle Lepage-Nefkens , Author ; Sophie Gerkens , Author ; Imgard Vinck , Author ; Julien Piérart , Author ; Frank Hulstaert, Author ; Maria-Isabel Farfan-Portet, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2013 . - 29 p. : Ill. ; A4. - (KCE Reports A. Health Services Research (HSR); 199AS) . ISSN : D/2013/10.273/11 : € 0,00 Studie n° 2012-13 Languages : Dutch (nla) Descriptors: Indexation 2012-13 ; Biosimilar Pharmaceuticals ; Cost Savings ; Economics, Hospital ; R199 ; Reimbursement Mechanisms Classification QV 241 Complex mixtures (General or not elsewhere classified) Abstract: Een biosimilar is een “look –alike” van een biologisch geneesmiddel, dat echter wel 20 tot 34 % goedkoper is dan het originele product. Vrij recent, in de zomer van 2012, nam de minister van Volksgezondheid maatregelen om het gebruik van biosimilaire geneesmiddelen aan te moedigen, zonder aanwijsbaar succes tot nu toe. Op vraag van de minister ging het Federaal Kenniscentrum voor de Gezondheidszorg (KCE) na waarom biosimilairen in ons land alsnog niet doorbreken. De kortingen (tot 75% voor sommige producten) en andere voordelen van de fabrikanten van de originelen aan de ziekenhuizen maken dat de biosimilairen uiteindelijk voor hen niet concurrentieel zijn. Tegelijkertijd betaalt het RIZIV de ziekenhuizen immers nog steeds terug op basis van de officiële prijs van het origineel. Daarnaast twijfelen veel artsen aan de doeltreffendheid en veiligheid van biosimilairen, en dit is zeker mee te wijten aan het gebrek aan informatie en klinische gegevens. Link for e-copy: https://doi.org/10.57598/R199AS Format of e-copy: PDF (712 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3173

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Barriers and opportunities for the uptake of biosimilar medicines in Belgium / Isabelle Lepage-Nefkens / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)  

Barriers and opportunities for the uptake of biosimilar medicines in Belgium [printed text] / Isabelle Lepage-Nefkens , Author ; Sophie Gerkens , Author ; Imgard Vinck , Author ; Julien Piérart , Author ; Frank Hulstaert, Author ; Maria-Isabel Farfan-Portet, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2013 . - 147 p. : Ill. ; A4. - (KCE Reports. Health Services Research (HSR); 199C) . ISSN : D/2013/10.273/13 : € 0,00 Study n° 2012-13 Languages : English (eng) Descriptors: Indexation 2012-13 ; Biosimilar Pharmaceuticals ; Cost Savings ; Economics, Hospital ; R199 ; Reimbursement Mechanisms Classification QV 241 Complex mixtures (General or not elsewhere classified) Link for e-copy: https://doi.org/10.57598/R199C Format of e-copy: PDF (2,1 MB) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3174

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Barriers and opportunities for the uptake of biosimilar medicines in Belgium / Isabelle Lepage-Nefkens / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)  

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Belgian guidelines for budget impact analyses / Mattias Neyt in Acta Clinica Belgica, 70(2015)03 ([06/01/2015])  

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Belrai suite of instruments / Anja Desomer / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2016)  

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Borstreconstructie na kanker / Sophie Gerkens / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2015)  

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Comparaison internationale des règles de remboursement et aspects légaux de la chirurgie plastique / Kristel De Gauquier / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2008)  

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Concentration des dépenses en soins de santé / Gungor Karakaya / Mutualités Libres (2013)

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Deciding on value for money / Margreet Franken in Value in Health, 13(2010)7 ([11/01/2010])  

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Een procedure voor de beoordeling van nieuwe medische hulpmiddelen / Imgard Vinck / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2006)  

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Etude des disparités de la chirurgie élective en Belgique / Jessica Jacques / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2006)  

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Étude de faisabilité de l’introduction en Belgique d’un système de financement hospitalier «all-in» par pathologie / Stefaan Van de Sande / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2010)  

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