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Adult obesity and number of years lived with and without cardiovascular disease / M.C. Pardo Silva in Obesity, 14(2006)7 ([07/01/2006])
[article] Adult obesity and number of years lived with and without cardiovascular disease [printed text] / M.C. Pardo Silva, Author ; Chris De Laet , Author ; W.J. Nusselder, Author ; A.A. Mamun, Author ; A. Peeters, Author . - 2006 . - 1264-73.
Languages : English (eng)
in Obesity > 14(2006)7 [07/01/2006] . - 1264-73
Descriptors: Classification
W 1 Serials. Periodicals
Indexation
Aging ; Body Mass Index ; Cardiovascular diseases ; Cost of Illness ; Female ; Humans ; Journal Article ; Life Expectancy ; Male ; Middle Aged ; Myocardial infarction ; Obesity ; Overweight ; Peer Review ; Risk Assessment ; Risk Factors ; Stroke ; Time Factors ; United StatesAbstract: OBJECTIVE: To determine the differences in number of years lived free of cardiovascular disease (CVD) and number of years lived with CVD between men and women who were obese, pre-obese, or normal weight at 45 years of age.
RESEARCH METHODS AND PROCEDURES: We constructed multistate life tables for CVD, myocardial infarction, and stroke, using data from 2551 enrollees (1130 men) in the Framingham Heart Study who were 45 years of age.
RESULTS: Obesity and pre-obesity were associated with fewer number of years free of CVD, myocardial infarction, and stroke and an increase in the number of years lived with these diseases. Forty-five-year-old obese men with no CVD survived 6.0 years [95% confidence interval (CI), 4.1; 8.1] fewer than their normal weight counterparts, whereas, for women, the difference between obese and normal weight subjects was 8.4 years (95% CI: 6.2; 10.8). Obese men and women lived with CVD 2.7 (95% CI: 1.0; 4.4) and 1.4 years (95% CI: -0.3; 3.2) longer, respectively, than normal weight individuals.
DISCUSSION: In addition to reducing life expectancy, obesity before middle age is associated with a reduction in the number of years lived free of CVD and an increase in the number of years lived with CVD. Such information is paramount for preventive and therapeutic decision-making by individuals and practitioners alike.Link for e-copy: http://www.nature.com/oby/journal/v14/n7/pdf/oby2006144a.pdf Format of e-copy: PDF [Open Access] (Embargo 2 years) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=2154 [article]Age-related changes in human blood lymphocyte subpopulations / F. Erkeller-Yuksel in The Journal of Pediatrics, 120(1996)2 ([02/01/1996])
[article] Age-related changes in human blood lymphocyte subpopulations [printed text] / F. Erkeller-Yuksel, Author ; V. Deneys, Author ; B. Yuksel, Author ; I. Hannet, Author ; Frank Hulstaert, Author ; C. Hamilton, Author . - 1996 . - 216-222.
Languages : English (eng)
in The Journal of Pediatrics > 120(1996)2 [02/01/1996] . - 216-222
Descriptors: Classification
W 1 Serials. Periodicals
Indexation
Adolescent ; Adult ; Aged ; Aging ; Antigens, CD ; Child ; Child, Preschool ; Female ; Fetal Blood ; Humans ; Immunophenotyping ; Infant ; Journal Article ; Leukocyte Count ; Lymphocyte Subsets ; Male ; Middle Aged ; Peer Review ; United StatesAbstract: Flow cytometric analysis of major lymphocyte populations and their subsets reveals age-related changes in the cellular human immune system. Immunophenotypic markers were evaluated in 110 normal pediatric subjects, divided into groups of newborn infants, infants aged 2 days to 11 months, and children aged 1 to 6 years and 7 to 17 years; results were then compared with those obtained from 101 normal adults aged 18 to 70 years. Comparisons among age groups from newborn infants through adults reveal progressive declines in the absolute numbers of leukocytes, total lymphocytes, and T, B, and natural killer (NK) cells. The percentages of T cells within the total lymphocyte population increase with age, in both CD4+ and CD8+ subsets. Percentages of B and NK cells are higher in newborn infants than in adults. The expression of the activation markers interleukin-2R and HLA-DR on T cells increases with age, as does the NK-associated expression of CD57 on CD8 cells. The proportions of B lymphocytes that coexpress CD5 or CDw78 decrease with age, whereas expression of Leu-8 and CD23 increases. The proportion of CD4 cells bearing the CD45RA and Leu-8 markers is consistently lower in adults than in children. These data may serve as a reference range for studies of pediatric subjects. Link for e-copy: http://www.sciencedirect.com/science/journal/00223476 Format of e-copy: PDF [Requires Subscription] Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=2187 [article]Age-related changes in human blood lymphocyte subpopulations / Frank Hulstaert in Clinical immunology and immunopathology, 70(1994)02 ([02/01/1994])
[article] Age-related changes in human blood lymphocyte subpopulations : II. Varying Kinetics of Percentage and Absolute Count Measurements [printed text] / Frank Hulstaert, Author ; I. Hannet, Author ; V. Deneys, Author ; V. Munhyeshuli, Author ; T. Reichert, Author ; M. De Bruyere, Author ; K. Strauss, Author . - 1994 . - 152-158.
Languages : English (eng)
in Clinical immunology and immunopathology > 70(1994)02 [02/01/1994] . - 152-158
Descriptors: Classification
W 1 Serials. Periodicals
Indexation
Adolescent ; Adult ; Aging ; Antigens, CD ; Antigens, Differentiation ; Child ; Child, Preschool ; Female ; Humans ; Immunophenotyping ; Infant ; Infant, Newborn ; Journal Article ; Leukocyte Count ; Male ; Middle Aged ; T-Lymphocytes ; United StatesAbstract: A reference range for lymphocyte populations, with particular emphasis on T lymphocyte subsets, was obtained for normal individuals covering age cohorts from birth through adulthood. This report confirms and extends findings from a developmental reference range published earlier (1). Absolute numbers of WBC, lymphocytes, and T, B, and NK subsets decline significantly during childhood. However, differences in the rate of decline of certain lymphocyte subsets leads to discordance between absolute numbers and percentages. Those lymphocyte subsets which decline less rapidly with age than the total lymphocyte count will show an increase in percentage, whereas those which decline more rapidly will show further declines in percentage values. T cell percentages were seen to increase over time whereas B cell percentages decline. Markers of immaturity such as CD45RA on CD4 cells and CD38 on CD8 cells declined in both percentages and absolute numbers. Activation markers, such as HLA-DR on CD8 cells and IL2-R on CD3 cells, increased in percentages with time but changed inconsistently in cell number from infancy to adulthood. These findings extend the lymphocyte references range to markers thought to be informative in various disease states, including HIV infection. Link for e-copy: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WCK-45R79S2-9&_user=1 [...] Format of e-copy: VDIC IP recognition Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=2209 [article]
AgeLine® Database [electronic document] . - EBSCO Industries, [s.d.].
Languages : English (eng)
Descriptors: Classification
WT 104 Aging process
Indexation
Aging ; Databases, BibliographicAbstract: AgeLine® focuses exclusively on the population aged 50+ and issues of aging. AgeLine is the premier source for the literature of social gerontology and includes aging-related content from the health sciences, psychology, sociology, social work, economics, and public policy. AgeLine also includes information for professionals working in aging-related fields and for consumers.
Original abstracts are generated for every citation, with index terms drawn from AgeLine's Thesaurus of Aging Terminology. AgeLine indexes over 600 journals, books, book chapters, reports, dissertations, consumer guides, and educational videos. Designed for researchers, professionals, students, and general consumers, this database addresses aging issues from individual, national, and global perspectives.
If AgeLine® is of interest, the following items may be of interest as well:
* Alt HealthWatch™
* AMED
* British Nursing Index
* Consumer Health Complete™
* Health Library
* Health Source®: Consumer Edition
* Health Source®: Nursing/Academic Edition
* MedicLatina
* MEDLINE® with Full Text
* Natural & Alternative Treatments
* SPORTDiscus™ with Full Text
Link for e-copy: https://www.ebscohost.com/academic/ageline Format of e-copy: Online [Requires Subscription] Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=1078 Base documentaire du Centre de liaison d'étude d'information et de recherche sur les problèmes des personnes âgées (CLEIRPPA) / Centre de liaison d'étude d'information et de recherche sur les problèmes des personnes âgées (C
Base documentaire du Centre de liaison d'étude d'information et de recherche sur les problèmes des personnes âgées (CLEIRPPA) [electronic document] . - Centre de liaison d'étude d'information et de recherche sur les problèmes des personnes âgées (C, [s.d.].
Languages : French (fre)
Descriptors: Classification
WT 104 Aging process
Indexation
Aging ; Databases, BibliographicAbstract: La base CLEIRPPA porte essentiellement sur des articles, extraits d'ouvrages, communications publiés depuis 1960 et constituant les dossiers documentaires du CLEIRPPA.
Le vocabulaire d'indexation utilisé pour les mots-clés est accessible en ligne.Link for e-copy: http://www.fng.fr/html/documentation/recherche_base/cleirppa/Default.htm Format of e-copy: Online [Free] Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=1087 Base documentaire de la Fondation nationale de Gérontologie (FNG) / Fondation nationale de Gérontologie (FNG)
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