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Diagnosis and management of gonorrhoea and syphilis / Vicky Jespers / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2019)
Diagnosis and management of gonorrhoea and syphilis [printed text] / Vicky Jespers , Author ; Sabine Stordeur, Author ; Anja Desomer, Author ; Serena Carville, Author ; Clare Jones, Author ; Sedina Lewis, Author ; Mark Perry, Author ; Sam Cordyn, Author ; Tine Cornelissen, Author ; Tania Crucitti, Author ; Céline Danhier, Author ; Irith De Baetselier, Author ; Anne-Sophie De Cannière, Author ; Wouter Dhaeze, Author ; Els Dufraimont, Author ; Chris Kenyon, Author ; Agnes Libois, Author ; Saphia Mokrane, Author ; Elizaveta Padalko, Author ; Sandra Van Den Eynde, Author ; Wim Vanden Berghe, Author ; Thierry Van Der Schueren, Author ; Nicole Dekker, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2019 . - 181 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 310C) .
ISSN : D/2019/10.273/21 : € 0,00
Languages : English (eng)
Descriptors: Indexation
2017-09 ; Chlamydia trachomatis ; Practice Guideline [Publication type] ; Primary Health Care ; R310 ; Sexually Transmitted Diseases ; Syphilis
Classification
WA 110 Prevention and control of communicable diseases. Transmission of infectious diseasesContents note: SCIENTIFIC REPORT 14 -- 1 INTRODUCTION .14 -- 1.1 BACKGROUND 14 -- Etiology, transmission, clinical features and epidemiological trends .14 -- Notification of infectious diseases in Belgium . 21 -- 1.2 THE NEED FOR A NATIONAL GUIDELINE .22 -- 1.3 SCOPE .23 -- 1.4 REMIT OF THE GUIDELINE .24 -- Overall objectives .24 -- Patient-centred care 24 -- Policy relevance and target users of the guideline .24 -- 1.5 STATEMENT OF INTENT 25 -- 1.6 FUNDING AND DECLARATION OF INTEREST 25 -- 2 METHODOLOGY 26 -- 2.1 THE GUIDELINE DEVELOPMENT GROUP 26 -- 2.2 INTERNATIONAL COLLABORATION .26 -- 2.3 GENERAL APPROACH AND CLINICAL RESEARCH QUESTIONS 26 -- General approach 26 -- Research questions 28 -- 2.4 SEARCH FOR GUIDELINES AND QUALITY APPRAISAL 34 -- Databases and date limits 34 -- Search strategy 34 -- Quality appraisal 36 -- 2.5 ADDITIONAL LITERATURE SEARCH: DIAGNOSTIC TESTS FOR GONORRHOEA 36 -- Diagnostic tests of choice for diagnosis of gonorrhoea in primary care 36 -- Quality appraisal 37 -- 2.6 ADDITIONAL LITERATURE SEARCH: TREATMENT FOR GONORRHOEA 38 -- Treatment for gonorrhoea in primary care 38 -- Quality appraisal 39 -- 2.7 ADDITIONAL LITERATURE SEARCH: DIAGNOSTIC TESTS FOR SYPHILIS 39 -- Search strategy .39 -- Quality appraisal 40 -- 2.8 ADDITIONAL LITERATURE SEARCH: TREATMENT FOR SYPHILIS .40 -- Treatment for syphilis in primary care 40 -- Quality appraisal 42 -- 2.9 DATA EXTRACTION .43 -- 2.10 STATISTICAL ANALYSES .43 -- 2.11 GRADING EVIDENCE .44 -- 2.12 FORMULATION OF RECOMMENDATIONS 47 -- 2.13 EXTERNAL REVIEW 49 -- 2.14 FINAL VALIDATION 50 -- 3 CLINICAL RECOMMENDATIONS 51 -- 3.1 ASSESSMENT OF RISK FOR GONORRHOEA 51 -- 3.2 DIAGNOSIS OF GONORRHOEA 52 -- Recommendations from international guidelines .53 -- Additional literature search: Diagnosis of gonorrhoea 56 -- Recommendations: Who to test for gonorrhoea 76 -- Recommendations: Diagnostic tests for gonorrhoea in men .77 -- Recommendations: Diagnostic tests for gonorrhoea in women 78 -- Diagnosis of gonorrhoea: Good practice statements .79 -- 3.3 TREATMENT OF GONORRHOEA: INFORMATION AND ADVICE FOR THE PATIENT 79 -- Recommendations from international guidelines .79 -- Recommendations regarding information and advice for the patient 80 -- 3.4 TREATMENT OF GONORRHOEA: TIMING OF INITIATION OF THERAPY .81 -- Recommendations from international guidelines .81 -- Recommendations regarding testing and surveillance for resistance 82 -- Recommendation regarding initiation of therapy .82 -- 3.5 TREATMENT OF GONORRHOEA: WHEN TO REFER TO SECOND LINE 83 -- Recommendations from international guidelines .83 -- Referral to the second line for gonorrhoea: Good practice statements 84 -- 3.6 TREATMENT OF GONORRHOEA: REFINING ACCORDING TO ANTIMICROBIAL RESISTANCE 84 -- Recommendations from international guidelines .84 -- Antimicrobial resistance: Belgian data 85 -- 3.7 TREATMENT OF GONORRHOEA: TREATMENT CHOICE IN MEN AND WOMEN .87 -- Recommendations from international guidelines .87 -- Recommendations from national guides .92 -- Additional literature search: Treatment of gonorrhoea in women and men, including young people 93 -- Recommendation for treatment of gonorrhoea in women and men including young people 99 -- Treatment of gonorrhea: Good practice statements 99 -- 3.8 TREATMENT OF GONORRHOEA: TREATMENT CHOICE IN PREGNANT WOMEN 100 -- Recommendations from international guidelines 100 -- Recommendations from national guides 101 -- Additional literature search: Treatment of gonorrhoea in pregnant women .101 -- Recommendation for treatment of gonorrhoea in pregnant women 104 -- Treatment of gonorrhoea in pregnant women: Good practice statements 104 -- 3.9 TREATMENT OF GONORRHOEA: TREATMENT CHOICE IN PEOPLE WITH AN ALLERGY TO CEPHALOSPORIN 105 -- Background cephalosporin allergy 105 -- Recommendations from international guidelines 105 -- Recommendations from national guides 106 -- Additional literature search: Treatment of gonorrhoea in people with an allergy to cephalosporin 106 -- Treatment of gonorrhoea in people with an allergy to cephalosporin: Good practice statement 106 -- Recommendations for treatment of chlamydia and gonorrhoea co-infection .107 -- 3.10 TEST OF CURE AND FOLLOW-UP FOR GONORRHOEA 107 -- Recommendations from international guidelines 107 -- Recommendations from national guides 109 -- Recommendations regarding a test of cure for gonorrhoea 110 -- Recommendations regarding testing frequency for gonorrhoea 111 -- 3.11 NOTIFICATION OF GONORRHOEA .111 -- Recommendations from international guidelines 111 -- Mandatory notification of gonorrhoea .112 -- 3.12 ASSESSMENT OF RISK FOR SYPHILIS 112 -- 3.13 DIAGNOSIS OF SYPHILIS .113 -- Diagnostic tests and testing approach for syphilis 113 -- Recommendations from international and national guidelines 119 -- Additional literature search: Diagnosis of syphilis .123 -- Recommendations: Who to test for syphilis .140 -- Recommendations: Which sample to take for syphilis diagnosis .141 -- Recommendation: Which tests for syphilis diagnosis .141 -- Choice of tests for syphilis diagnosis: Good practice statements .142 -- 3.14 TREATMENT OF SYPHILIS: INFORMATION AND ADVICE FOR THE PATIENT 142 -- Recommendations from international guidelines 142 -- Recommendations regarding syphilis information and advice for the patient 143 -- 3.15 TREATMENT OF SYPHILIS: INITIATION OF THERAPY AND REFERRAL TO SECOND LINE 143 -- Recommendation regarding initiation of syphilis therapy .143 -- Recognising syphilis clinical symptoms: Good practice statements 144 -- When to refer the patient to the second line for syphilis: Good practice statements 144 -- 3.16 TREATMENT OF SYPHILIS: TREATMENT CHOICE IN MEN AND WOMEN 145 -- Recommendations from international guidelines 145 -- Recommendations from national guides 150 -- Additional literature search: Treatment of uncomplicated syphilis in women and men including young people 151 -- Recommendations for treatment of syphilis in women and men and young people (excluding pregnant women) 163 -- Treatment of syphilis: Good practice statements 163 -- 3.17 TREATMENT OF UNCOMPLICATED SYPHILIS IN CASE OF ALLERGY TO PENICILLIN 164 -- 3.18 TEST OF CURE, FOLLOW-UP AND REFERRAL FOR SYPHILIS 164 -- Recommendations from international guidelines 164 -- Recommendations regarding follow-up of a treated patient 166 -- Testing frequency for syphilis: Good practice statements 167 -- 3.19 NOTIFICATION OF SYPHILIS 167 -- Recommendations from international guidelines 167 -- Mandatory notification of syphilis 167 -- 4 IMPLEMENTATION 168 -- 4.1 IMPLEMENTATION OF THE SCIENTIFIC REPORT DOCUMENT 168 -- 4.2 TRANSLATING THE GUIDELINE INTO A PRIMARY CARE SEXUAL HEALTH CONSULTATION STI TESTING TOOL 168 -- Clinical guidance 168 -- Overview of guidance documents .168 -- Structure of the STI consultation tool 170 -- 4.3 POLICY AND OTHER IMPLEMENTATION OF THIS GUIDELINE 171 -- Barriers and facilitators 171 -- Actors 172 -- 5 GUIDELINE UPDATE 172 -- REFERENCES 173 Link for e-copy: https://doi.org/10.57598/R310C Format of e-copy: PDF (2,4 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4528 Diagnosis and management of gonorrhoea and syphilis / Vicky Jespers / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2023)
Diagnosis and management of gonorrhoea and syphilis : Appendix [printed text] / Vicky Jespers , Author ; Sabine Stordeur, Author ; Anja Desomer, Author ; Serena Carville, Author ; Clare Jones, Author ; Sedina Lewis, Author ; Mark Perry, Author ; Sam Cordyn, Author ; Tine Cornelissen, Author ; Tania Crucitti, Author ; Céline Danhier, Author ; Irith De Baetselier, Author ; Anne-Sophie De Cannière, Author ; Wouter Dhaeze, Author ; Els Dufraimont, Author ; Chris Kenyon, Author ; Agnes Libois, Author ; Saphia Mokrane, Author ; Elizaveta Padalko, Author ; Sandra Van Den Eynde, Author ; Wim Vanden Berghe, Author ; Thierry Van Der Schueren, Author ; Nicole Dekker, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2023 . - 329 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 371S) .
ISSN : D/2023/10.273/28 : € 0,00
Languages : English (eng)
Descriptors: Indexation
2017-09 ; Chlamydia trachomatis ; Practice Guideline [Publication type] ; Primary Health Care ; R371 ; Sexually Transmitted Diseases ; Syphilis
Classification
WA 110 Prevention and control of communicable diseases. Transmission of infectious diseasesContents note: APPENDIX REPORT 1 -- TABLE OF CONTENTS 1 -- LIST OF FIGURES 4 -- LIST OF TABLES 10 -- 1. COMPOSITION OF THE GUIDELINE DEVELOPMENT GROUP 12 -- 1.1. COMPOSITION OF THE GUIDELINE DEVELOPMENT GROUP 12 -- 1.2. COMPOSITION OF THE KCE EXPERT TEAM 13 -- 1.3. EXTERNAL RESEARCHERS INVOLVED IN THE GUIDELINE DEVELOPMENT 13 -- 2. SEARCH STRATEGIES 14 -- 2.1. GENERAL LITERATURE SEARCH (FIRST EDITION 2019) 14 -- 2.1.1. Ovid MEDLINE 14 -- 2.1.2. Cochrane 15 -- 2.1.3. Embase 18 -- 2.1.4. Study flow for general literature search 21 -- 2.2. ADDITIONAL SEARCH FOR DIAGNOSIS OF GONORRHOEA (FIRST EDITION 2019) 22 -- 2.2.1. Medline 22 -- 2.2.2. Central 22 -- 2.2.3. Study flow of selection of primary studies 23 -- 2.2.4. Excluded studies 24 -- 2.3. ADDITIONAL SEARCH FOR TREATMENT OF GONORRHEA (FIRST EDITION 2019) 28 -- 2.3.1. Medline 28 -- 2.3.2. Embase 29 -- 2.3.3. Cochrane 30 -- 2.3.4. Study flow of selection of primary studies 31 -- 2.3.5. Excluded studies 33 -- 2.4. ADDITIONAL SEARCH FOR DIAGNOSIS OF SYPHILIS (FIRST EDITION 2019) 35 -- 2.4.1. Medline 35 -- 2.4.2. Cochrane 36 -- 2.4.3. Study flow of selection of systematic reviews and primary studies 37 -- 2.4.4. Excluded studies 38 -- 2.5. ADDITIONAL SEARCH FOR TREATMENT OF SYPHILIS (FIRST EDITION 2019) 39 -- 2.5.1. Medline 39 -- 2.5.2. Embase 40 -- 2.5.3. Cochrane 40 -- 2.5.4. Pubmed 41 -- 2.5.5. Excluded studies 43 -- 3. GUIDELINES IDENTIFIED 44 -- 3.1. TOPIC: DIAGNOSIS AND/OR MANAGEMENT OF GONORRHOEA (FIRST EDITION 2019) 44 -- 3.2. TOPIC: DIAGNOSIS AND/OR MANAGEMENT OF GONORRHOEA (SECOND EDITION 2023) 45 -- 3.3. TOPIC: DIAGNOSIS AND/OR MANAGEMENT OF SYPHILIS (FIRST EDITION 2019) 45 -- 4. GUIDANCE DOCUMENTS AND CONSULTATION ALGORITHMS FOR THE TOOL 47 -- 5. GUIDANCE DOCUMENTS FOR PARTNER MANAGEMENT 49 -- 6. QUALITY APPRAISAL 51 -- 6.1. QUALITY APPRAISAL TOOLS 51 -- 6.1.1. Guidelines 51 -- 6.1.2. Diagnostic accuracy studies 56 -- 6.1.3. Primary studies for therapeutic interventions 61 -- 7. EVIDENCE TABLES BY CLINICAL QUESTION 75 -- 7.1. DIAGNOSIS OF GONORRHEA 75 -- 7.1.1. Nucleic acid amplification Tests (NAATs) and culture 75 -- 7.2. TREATMENT OF GONORRHOEA 139 -- 7.2.1. Sexually active women and men including adolescents 139 -- 7.2.2. Pregnant women 147 -- 7.2.3. People with an allergy to cephalosporin 152 -- 7.3. DIAGNOSIS OF SYPHILIS 153 -- 7.3.1. Screening strategies 153 -- 7.3.2. Polymerase Chain Reaction (PCR) assay 156 -- 7.3.3. Enzyme Immunoassay (EIA) 159 -- 7.3.4. Rapid point of care (POC) tests for syphilis 163 -- 7.4. TREATMENT OF SYPHILIS 179 -- 7.4.1. Research question 7 – What is the recommended treatment for uncomplicated syphilis in sexually active women and men including young people? 179 -- 7.4.2. Research question 8 – What is the recommended treatment for uncomplicated syphilis in case of allergy to penicillin? 213 -- 8. FOREST PLOTS 214 -- 8.1. N. GONORRHOEA AND C. TRACHOMATIS: DIAGNOSIS 214 -- 8.2. N. GONORRHOEA: TREATMENT 221 -- 8.2.1. Sexually active women and men including young people 221 -- 8.2.2. Pregnant women 226 -- 8.2.3. People with severe cephalosporin allergy 230 -- 8.3. SYPHILIS: DIAGNOSIS 230 -- 8.4. SYPHILIS: TREATMENT 232 -- 8.4.1. Treatment of syphilis in women and men including young people 232 -- 8.5. RESEARCH QUESTION 8: TREATMENT OF SYPHILIS IN ADULTS IN CASE OF ALLERGY TO PENICILLIN 250 -- 9. SUMMARY OF FINDINGS TABLES AND GRADE PROFILES 251 -- 9.1. NEISSERIA GONORRHEA: DIAGNOSIS 251 -- 9.2. CHLAMYDIA TRACHOMATIS (ONLY FOR TMA APTIMA COMBO TEST): DIAGNOSIS 256 -- 9.3. NEISSERIA GONORRHEA: TREATMENT 258 -- 9.3.1. Treatment of gonorrhea in sexually active women and men 258 -- 9.3.2. Treatment for pregnant women 262 -- 9.3.3. Treatment for people with severe cephalosporin allergy 264 -- 9.4. SYPHILIS: DIAGNOSIS 264 -- 9.5. SYPHILIS: TREATMENT 268 -- 10. NEISSERIA GONORRHOEA RESISTANCE: BELGIAN DATA 281 -- 11. 6 STEPS FOR TESTING STIS IN A SEXUAL HEALTH CONSULTATION 283 -- 11.1. STEP 1: STARTING A CONVERSATION ABOUT SEXUAL HEALTH TESTING 283 -- 11.2. STEP 2 : SEXUAL HISTORY QUESTIONS FOR READINESS, NEEDS AND RISK ASSESSMENT 284 -- 11.3. STEP 3 : STI TESTING OVERVIEW 285 -- 11.4. STEP 4 : HOW TO TEST 287 -- 11.5. STEP 5 : TREATMENT OVERVIEW - TEST OF CURE - FOLLOW UP 288 -- 11.6. STEP 6 : PARTNER MANAGEMENT AND CONTACT 290 -- 12. UPDATE 2023 292 -- 12.1. QUESTIONS FOR THE GDG 292 -- 12.1.1. General questions update 292 -- 12.1.2. Overarching concepts 292 -- 12.1.3. Treatment uncomplicated gonorrhoea (+chlamydia) 293 -- 12.1.4. Test of cure 294 -- 12.2. SUMMARY OF THE GDG REVIEW OF THE DRAFT RECOMMENDATIONS 295 -- 12.2.1. General questions update 295 -- 12.2.2. Overarching concepts 296 -- 12.2.3. Treatment uncomplicated gonorrhoea (+chlamydia) 298 -- 12.2.4. Test of cure 302 -- 12.3. 2023 NEW RECOMMENDATIONS 305 -- REFERENCES 307 Link for e-copy: https://doi.org/10.57598/R371S Format of e-copy: PDF (3,4 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4949 Diagnosis and management of gonorrhoea and syphilis / Vicky Jespers / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2019)
Diagnosis and management of gonorrhoea and syphilis : Appendix [printed text] / Vicky Jespers , Author ; Sabine Stordeur, Author ; Anja Desomer, Author ; Serena Carville, Author ; Clare Jones, Author ; Sedina Lewis, Author ; Mark Perry, Author ; Sam Cordyn, Author ; Tine Cornelissen, Author ; Tania Crucitti, Author ; Céline Danhier, Author ; Irith De Baetselier, Author ; Anne-Sophie De Cannière, Author ; Wouter Dhaeze, Author ; Els Dufraimont, Author ; Chris Kenyon, Author ; Agnes Libois, Author ; Saphia Mokrane, Author ; Elizaveta Padalko, Author ; Sandra Van Den Eynde, Author ; Wim Vanden Berghe, Author ; Thierry Van Der Schueren, Author ; Nicole Dekker, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2019 . - 305 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 310S) .
ISSN : D/2019/10.273/22 : € 0,00
Languages : English (eng)
Descriptors: Indexation
2017-09 ; Chlamydia trachomatis ; Practice Guideline [Publication type] ; Primary Health Care ; R310 ; Sexually Transmitted Diseases ; Syphilis
Classification
WA 110 Prevention and control of communicable diseases. Transmission of infectious diseasesContents note: 1. COMPOSITION OF THE GUIDELINE DEVELOPMENT GROUP 12 -- 1.1. COMPOSITION OF THE GUIDELINE DEVELOPMENT GROUP 12 -- 1.2. COMPOSITION OF THE KCE EXPERT TEAM 13 -- 1.3. EXTERNAL RESEARCHERS INVOLVED IN THE GUIDELINE DEVELOPMENT 13 -- 2. SEARCH STRATEGIES 14 -- 2.1. GENERAL LITERATURE SEARCH 14 -- 2.1.1. Ovid MEDLINE 14 -- 2.1.2. Cochrane 15 -- 2.1.3. Embase 17 -- 2.1.4. Study flow for general literature search 21 -- 2.2. ADDITIONAL SEARCH FOR DIAGNOSIS OF GONORRHOEA 22 -- 2.2.1. Medline 22 -- 2.2.2. Central 22 -- 2.2.3. Study flow of selection of primary studies 22 -- 2.2.4. Excluded studies 24 -- 2.3. ADDITIONAL SEARCH FOR TREATMENT OF GONORRHEA 28 -- 2.3.1. Medline 28 -- 2.3.2. Embase 29 -- 2.3.3. Cochrane 30 -- 2.3.4. Study flow of selection of primary studies 31 -- 2.3.5. Excluded studies 33 -- 2.4. ADDITIONAL SEARCH FOR DIAGNOSIS OF SYPHILIS 35 -- 2.4.1. Medline 35 -- 2.4.2. Cochrane 36 -- 2.4.3. Study flow of selection of systematic reviews and primary studies 37 -- 2.4.4. Excluded studies 38 -- 2.5. ADDITIONAL SEARCH FOR TREATMENT OF SYPHILIS 39 -- 2.5.1. Medline 39 -- 2.5.2. Embase 40 -- 2.5.3. Cochrane 40 -- 2.5.4. Pubmed 41 -- 2.5.5. Excluded studies 43 -- 3. GUIDELINES IDENTIFIED 44 -- 3.1. TOPIC: DIAGNOSIS AND/OR MANAGEMENT OF GONORRHOEA 44 -- 3.2. TOPIC: DIAGNOSIS AND/OR MANAGEMENT OF SYPHILIS 45 -- 4. GUIDANCE DOCUMENTS AND CONSULTATION ALGORITHMS FOR THE TOOL 46 -- 5. GUIDANCE DOCUMENTS FOR PARTNER MANAGEMENT 48 -- 6. QUALITY APPRAISAL 50 -- 6.1. QUALITY APPRAISAL TOOLS 50 -- 6.1.1. Guidelines 50 -- 6.1.2. Diagnostic accuracy studies 54 -- 6.1.3. Primary studies for therapeutic interventions 59 -- 7. EVIDENCE TABLES BY CLINICAL QUESTION 73 -- 7.1. DIAGNOSIS OF GONORRHEA 73 -- 7.1.1. Nucleic acid amplification Tests (NAATs) and culture 73 -- 7.2. TREATMENT OF GONORRHOEA 136 -- 7.2.1. Sexually active women and men including adolescents 136 -- 7.2.2. Pregnant women 144 -- 7.2.3. People with an allergy to cephalosporin 150 -- 7.3. DIAGNOSIS OF SYPHILIS 150 -- 7.3.1. Screening strategies 151 -- 7.3.2. Polymerase Chain Reaction (PCR) assay 154 -- 7.3.3. Enzyme Immunoassay (EIA) 157 -- 7.3.4. Rapid point of care (POC) tests for syphilis 161 -- 7.4. TREATMENT OF SYPHILIS 177 -- 7.4.1. Research question 7 – What is the recommended treatment for uncomplicated syphilis in sexually active women and men including young people? 177 -- 7.4.2. Research question 8 – What is the recommended treatment for uncomplicated syphilis in case of allergy to penicillin? 211 -- 8. FOREST PLOTS 212 -- 8.1. N. GONORRHOEA AND C. TRACHOMATIS: DIAGNOSIS 212 -- 8.2. N. GONORRHOEA: TREATMENT 219 -- 8.2.1. Sexually active women and men including young people 219 -- 8.2.2. Pregnant women 224 -- 8.2.3. People with severe cephalosporin allergy 228 -- 8.3. SYPHILIS: DIAGNOSIS 228 -- 8.4. SYPHILIS: TREATMENT 230 -- 8.4.1. Treatment of syphilis in women and men including young people 230 -- 8.5. RESEARCH QUESTION 8: TREATMENT OF SYPHILIS IN ADULTS IN CASE OF ALLERGY -- TO PENICILLIN 248 -- 9. SUMMARY OF FINDINGS TABLES AND GRADE PROFILES 249 -- 9.1. NEISSERIA GONORRHEA: DIAGNOSIS 249 -- 9.2. CHLAMYDIA TRACHOMATIS (ONLY FOR TMA APTIMA COMBO TEST): DIAGNOSIS 254 -- 9.3. NEISSERIA GONORRHEA: TREATMENT 256 -- 9.3.1. Treatment of gonorrhea in sexually active women and men 256 -- 9.3.2. Treatment for pregnant women 260 -- 9.3.3. Treatment for people with severe cephalosporin allergy 262 -- 9.4. SYPHILIS: DIAGNOSIS 262 -- 9.5. SYPHILIS: TREATMENT 266 -- 10. NEISSERIA GONORRHOEA RESISTANCE: BELGIAN DATA 278 -- 11. 6 STEPS FOR TESTING STIS IN A SEXUAL HEALTH CONSULTATION 280 -- STEP 1: STARTING A CONVERSATION ABOUT SEXUAL HEALTH TESTING 280 -- STEP 2 : SEXUAL HISTORY QUESTIONS FOR READINESS, NEEDS AND RISK ASSESSMENT 281 -- STEP 3 : STI TESTING OVERVIEW 282 -- STEP 4 : HOW TO TEST 284 -- STEP 5 : TREATMENT OVERVIEW - TEST OF CURE - FOLLOW UP 285 -- STEP 6 : PARTNER MANAGEMENT AND CONTACT 287 -- REFERENCES 289 Link for e-copy: https://doi.org/10.57598/R310S Format of e-copy: PDF (3,4 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4529 Diagnosis and management of gonorrhoea and syphilis / Vicky Jespers / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2023)
Diagnosis and management of gonorrhoea and syphilis : Short report [printed text] / Vicky Jespers , Author ; Sabine Stordeur, Author ; Anja Desomer, Author ; Serena Carville, Author ; Clare Jones, Author ; Sedina Lewis, Author ; Mark Perry, Author ; Sam Cordyn, Author ; Tine Cornelissen, Author ; Tania Crucitti, Author ; Céline Danhier, Author ; Irith De Baetselier, Author ; Anne-Sophie De Cannière, Author ; Wouter Dhaeze, Author ; Els Dufraimont, Author ; Chris Kenyon, Author ; Agnes Libois, Author ; Saphia Mokrane, Author ; Elizaveta Padalko, Author ; Sandra Van Den Eynde, Author ; Wim Vanden Berghe, Author ; Thierry Van Der Schueren, Author ; Nicole Dekker, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2023 . - 48 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 371CS) .
€ 0,00
Languages : English (eng)
Descriptors: Indexation
2017-09 ; Chlamydia trachomatis ; Practice Guideline [Publication type] ; Primary Health Care ; R371 ; Sexually Transmitted Diseases ; Syphilis
Classification
WA 110 Prevention and control of communicable diseases. Transmission of infectious diseasesContents note: LIST OF FIGURES 4 -- LIST OF TABLES 4 -- 1 INTRODUCTION 7 -- BACKGROUND 7 -- REMIT OF THE GUIDELINE 9 -- 1.2.1 Objectives of the guideline 9 -- 1.2.2 Patient-centered care 9 -- 1.2.3 The need for an update of the guideline (2023) 9 -- 2 METHODOLOGY 10 -- THE GUIDELINE DEVELOPMENT GROUP 10 -- CLINICAL RESEARCH QUESTIONS 10 -- GENERAL APPROACH 11 -- QUALITY ASSESSMENT OF STUDIES 11 -- FORMULATION OF RECOMMENDATIONS 12 -- EXTERNAL REVIEW 12 -- FINAL VALIDATION 12 -- 2023 UPDATE 12 -- 3 CLINICAL RECOMMENDATIONS FOR MANAGEMENT OF GONORRHOEA 14 -- GONORRHOEA DIAGNOSIS 14 -- 3.1.1 Recommendations: Who to test for gonorrhoea 14 -- 3.1.2 Recommendations: Diagnostic tests for gonorrhoea 16 -- 3.1.3 Diagnosis of gonorrhoea: Good practice statements 18 -- GONORRHOEA TREATMENT 19 -- 3.2.1 Recommendations regarding information and advice for the patient 19 -- 3.2.2 Recommendations regarding testing and surveillance for resistance 20 -- 3.2.3 Recommendation regarding initiation of therapy 21 -- 3.2.4 Referral to the second line for gonorrhoea: Good practice statements 22 -- 3.2.5 Recommendation for treatment of gonorrhoea in women and men including young people 22 -- 3.2.6 Treatment of gonorrhoea: Good practice statements 23 -- 3.2.7 Recommendation for treatment of gonorrhoea in pregnant women 23 -- 3.2.8 Treatment of gonorrhoea in pregnant women: Good practice statements 23 -- 3.2.9 Treatment of gonorrhoea in people with an allergy to cephalosporin: Good practice statement 24 -- 3.2.10 Recommendations for treatment of chlamydia and gonorrhoea co-infection 24 -- GONORRHOEA TEST OF CURE AND FREQUENCY OF TESTING 25 -- 3.3.1 Recommendations regarding a test of cure for gonorrhoea 25 -- 3.3.2 Recommendations regarding testing frequency for gonorrhoea 26 -- MANDATORY NOTIFICATION OF GONORRHOEA 26 -- 4 CLINICAL RECOMMENDATIONS FOR MANAGEMENT OF SYPHILIS 27 -- SYPHILIS DIAGNOSIS 27 -- 4.1.1 Recommendations: Who to test for syphilis 27 -- 4.1.2 Recommendations: Which sample to take for syphilis 29 -- 4.1.3 Recommendation: Which tests to use for syphilis 29 -- 4.1.4 Choice of tests for syphilis diagnosis: Good practice statements 30 -- SYPHILIS TREATMENT 31 -- 4.2.1 Recommendations regarding syphilis information and advice for the patient 31 -- 4.2.2 Recommendation regarding initiation of syphilis therapy 31 -- 4.2.3 Recognising syphilis clinical symptoms: Good practice statements 31 -- 4.2.4 When to refer to the second line for syphilis: Good practice statements 32 -- 4.2.5 Recommendations for treatment of syphilis in women and men including young people (excluding pregnant women) 33 -- 4.2.6 Treatment of syphilis: Good practice statements 34 -- SYPHILIS FOLLOW-UP AND FREQUENCY OF TESTING 34 -- 4.3.1 Recommendations regarding follow-up of a treated patient 34 -- 4.3.2 Testing frequency for syphilis: Good practice statements 35 -- MANDATORY NOTIFICATION OF SYPHILIS 35 -- 5 IMPLEMENTATION OF THIS GUIDELINE 36 -- POLICY AND OTHER IMPLEMENTATION OF THIS GUIDELINE 36 -- 5.1.1 Barriers and facilitators 36 -- 5.1.2 Actors of dissemination and publication on Ebpractice net 36 -- TRANSLATING THE GUIDELINE INTO A PRIMARY CARE SEXUAL HEALTH CONSULTATION STI TESTING INSTRUMENT 37 -- 5.2.1 Clinical guidance 37 -- 5.2.2 Structure of the STI consultation instrument 37 -- 6 GUIDELINE UPDATE 39 -- RECOMMENDATIONS 40 -- REFERENCES 42 Link for e-copy: https://doi.org/10.57598/R371CS Format of e-copy: PDF (1,2 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4950 Diagnosis and management of gonorrhoea and syphilis / Vicky Jespers / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2019)
Diagnosis and management of gonorrhoea and syphilis : Short report [printed text] / Vicky Jespers , Author ; Sabine Stordeur, Author ; Anja Desomer, Author ; Serena Carville, Author ; Clare Jones, Author ; Sedina Lewis, Author ; Mark Perry, Author ; Sam Cordyn, Author ; Tine Cornelissen, Author ; Tania Crucitti, Author ; Céline Danhier, Author ; Irith De Baetselier, Author ; Anne-Sophie De Cannière, Author ; Wouter Dhaeze, Author ; Els Dufraimont, Author ; Chris Kenyon, Author ; Agnes Libois, Author ; Saphia Mokrane, Author ; Elizaveta Padalko, Author ; Sandra Van Den Eynde, Author ; Wim Vanden Berghe, Author ; Thierry Van Der Schueren, Author ; Nicole Dekker, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2019 . - 45 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 310CS) .
ISSN : D/2019/10.273/20 : € 0,00
Languages : English (eng)
Descriptors: Indexation
2017-09 ; Chlamydia trachomatis ; Practice Guideline [Publication type] ; Primary Health Care ; R310 ; Sexually Transmitted Diseases ; Syphilis
Classification
WA 110 Prevention and control of communicable diseases. Transmission of infectious diseasesContents note: 1 INTRODUCTION 7 -- BACKGROUND 7 -- REMIT OF THE GUIDELINE 9 -- 1.2.1 Objectives of the guideline 9 -- 1.2.2 Patient-centered care 9 -- 2 METHODOLOGY 10 -- THE GUIDELINE DEVELOPMENT GROUP 10 -- CLINICAL RESEARCH QUESTIONS 10 -- GENERAL APPROACH 11 -- QUALITY ASSESSMENT OF STUDIES 11 -- FORMULATION OF RECOMMENDATIONS 12 -- EXTERNAL REVIEW 12 -- FINAL VALIDATION 12 -- 3 CLINICAL RECOMMENDATIONS FOR MANAGEMENT OF GONORRHOEA 14 -- GONORRHOEA DIAGNOSIS 14 -- 3.1.1 Recommendations: Who to test for gonorrhoea 14 -- 3.1.2 Recommendations: Diagnostic tests for gonorrhoea 16 -- 3.1.3 Diagnosis of gonorrhoea: Good practice statements 18 -- GONORRHOEA TREATMENT 19 -- 3.2.1 Recommendations regarding information and advice for the patient 19 -- 3.2.2 Recommendations regarding testing and surveillance for resistance 20 -- 3.2.3 Recommendation regarding initiation of therapy 20 -- 3.2.4 Referral to the second line for gonorrhoea: Good practice statements 21 -- 3.2.5 Recommendation for treatment of gonorrhoea in women and men including young people 21 -- 3.2.6 Treatment of gonorrhoea: Good practice statements 22 -- 3.2.7 Recommendation for treatment of gonorrhoea in pregnant women 22 -- 3.2.8 Treatment of gonorrhoea in pregnant women: Good practice statements 23 -- 3.2.9 Treatment of gonorrhoea in people with an allergy to cephalosporin: Good practice statement 23 -- 3.2.10 Recommendations for treatment of chlamydia and gonorrhoea co-infection 24 -- GONORRHOEA TEST OF CURE AND FREQUENCY OF TESTING 25 -- 3.3.1 Recommendations regarding a test of cure for gonorrhoea 25 -- 3.3.2 Recommendations regarding testing frequency for gonorrhoea 26 -- MANDATORY NOTIFICATION OF GONORRHOEA 26 -- 4 CLINICAL RECOMMENDATIONS FOR MANAGEMENT OF SYPHILIS 27 -- SYPHILIS DIAGNOSIS 27 -- 4.1.1 Recommendations: Who to test for syphilis 27 -- 4.1.2 Recommendations: Which sample to take for syphilis 28 -- 4.1.3 Recommendation: Which tests to use for syphilis 29 -- 4.1.4 Choice of tests for syphilis diagnosis: Good practice statements 30 -- SYPHILIS TREATMENT 30 -- 4.2.1 Recommendations regarding syphilis information and advice for the patient 30 -- 4.2.2 Recommendation regarding initiation of syphilis therapy 31 -- 4.2.3 Recognising syphilis clinical symptoms: Good practice statements 31 -- 4.2.4 When to refer to the second line for syphilis: Good practice statements 32 -- 4.2.5 Recommendations for treatment of syphilis in women and men including young people (excluding pregnant women) 32 -- 4.2.6 Treatment of syphilis: Good practice statements 33 -- SYPHILIS FOLLOW-UP AND FREQUENCY OF TESTING 34 -- 4.3.1 Recommendations regarding follow-up of a treated patient 34 -- 4.3.2 Testing frequency for syphilis: Good practice statements 35 -- MANDATORY NOTIFICATION OF SYPHILIS 35 -- 5 IMPLEMENTATION OF THIS GUIDELINE 36 -- POLICY AND OTHER IMPLEMENTATION OF THIS GUIDELINE 36 -- 5.1.1 Barriers and facilitators 36 -- 5.1.2 Actors of dissemination and publication on Ebpractice net 36 -- TRANSLATING THE GUIDELINE INTO A PRIMARY CARE SEXUAL HEALTH CONSULTATION STI TESTING INSTRUMENT 37 -- 5.2.1 Clinical guidance 37 -- 5.2.2 Structure of the STI consultation instrument 37 -- 6 GUIDELINE UPDATE 39 -- RECOMMENDATIONS 40 -- REFERENCES 42 Link for e-copy: https://doi.org/10.57598/R310CS Format of e-copy: PDF (1,4 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4527 Diagnosis and treatment of gonorrhoea / Vicky Jespers in Acta Clinica Belgica, (2020) Online ([06/02/2020])
PermalinkDiagnosis and treatment of syphilis / Vicky Jespers in Acta Clinica Belgica, (2020) Online ([06/02/2020])
PermalinkDiagnostic et prise en charge de la gonorrhée et de la syphilis / Vicky Jespers / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2023)
PermalinkDiagnostic et prise en charge de la gonorrhée et de la syphilis / Vicky Jespers / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2019)
PermalinkDo quality improvements in primary care reduce secondary care costs? / Stephen Martin / London [United Kingdom] : The Health Foundation (2010)
PermalinkDrug substitution associated with a hospital stay in Belgium / Simoens, Steven in International Journal of Pharmacy Practice, 22(2014)02 ([04/01/2014])
PermalinkEffective Responses to the Clinical Challenges in Chronic Care Delivery / Geert Goderis / Leuven [Belgium] : Katholieke Universiteit Leuven (KUL) (2010)
PermalinkEncouraging the people of Europe to practise self care / Ruth Chambers / Utrecht [Netherlands] : European Forum for Primary Care (2006)
PermalinkEvaluating fracture risk in acute ankle sprains / Pascale Jonckheer in European Journal of General Practice, 1751-1402 - Online ([12/22/2015])
PermalinkICPC-1: International Classification of Primary Care / Utrecht [The Netherlands] : Nederlands Huisartsen Genootschap (NHG) (2010)
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