Descriptors
Documents disponibles dans cette catégorie (11)
Add the result to your basket Make a suggestion Refine your search Apply to external sources
Extend search on down-posting(s)
Analytical performance and clinical utility of the INNOTEST PHOSPHO-TAU181P assay for discrimination between Alzheimer's disease and dementia with Lewy bodies. / H. Vanderstichele in Clinical chemistry and laboratory medicine, 44(2006)12 ([01/01/2006])
[article] Analytical performance and clinical utility of the INNOTEST PHOSPHO-TAU181P assay for discrimination between Alzheimer's disease and dementia with Lewy bodies. [printed text] / H. Vanderstichele, Author ; K. De Vreese, Author ; K. Blennow, Author ; N. Andreasen, Author ; C. Sindic, Author ; A. Ivanoiu, Author ; H. Hampel, Author ; K. Burger, Author ; L. Parnetti, Author ; A. Padovani, Author ; M. Di Luca, Author ; M. Blaser, Author ; A.O. Olsson, Author ; H. Pottel, Author ; Frank Hulstaert, Author ; E. Vanmechelen, Author . - 2006.
Languages : English (eng)
in Clinical chemistry and laboratory medicine > 44(2006)12 [01/01/2006]
Descriptors: Classification
W 1 Serials. Periodicals
Indexation
Aged ; Alzheimer Disease ; Amyloid beta-Peptides ; Biological Markers ; Diagnosis, Differential ; Discriminant Analysis ; Enzyme-Linked Immunosorbent Assay ; Female ; Germany ; Humans ; Journal Article ; Lewy Body Disease ; Logistic Models ; Male ; Middle Aged ; Peer Review ; Peptide Fragments ; Reproducibility of Results ; Sensitivity and specificityAbstract: BACKGROUND: Total tau (T-tau) and beta-amyloid((1-42)) (Abeta(1-42)) levels in cerebrospinal fluid (CSF) can differentiate Alzheimer's disease (AD) from normal aging or depressive pseudo-dementia. Differential diagnosis from dementia with Lewy bodies (DLB) in clinical settings is difficult.
METHODS: The analytical performance of the INNOTEST PHOSPHO-TAU(181P) assay was validated in terms of selectivity, sensitivity, specificity, precision, robustness, and stability. Clinical utility of the assay alone, or combined with T-tau and Abeta(1-42), for discrimination of AD (n=94) from patients suffering from DLB (n=60) or from age-matched control subjects (CS) (n=60) was assessed in a multicenter study.
RESULTS: CSF concentrations of tau phosphorylated at threonine 181 (P-tau(181P)) in AD was significantly higher than in DLB and CS. Discriminant analysis, a classification tree, and logistic regression showed that P-tau(181P) was the most statistically significant single variable of the three biomarkers for discrimination between AD and DLB.
CONCLUSIONS: P-tau(181P) quantification is a robust and reliable assay that may be useful in discriminating AD from DLB.Link for e-copy: http://dx.doi.org/10.1515/CCLM.2006.258 Format of e-copy: PDF [Requires Subscription] Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=2205 [article]Het nut van atheromathose-merkers bij het bepalen van het cardiovasculair risico / Dominique Roberfroid / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2015)
Het nut van atheromathose-merkers bij het bepalen van het cardiovasculair risico : Synthese [printed text] / Dominique Roberfroid , Author ; Lorena San Miguel , Author ; Dominique Paulus , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2015 . - 11 p. : Ill., ; A4. - (KCE Reports A. Health Technology Assessment (HTA); 244As) .
ISSN : D/2015/10.273/40 : € 0,00
Studie 2013-29_HTA_Risk_Markers_CVD
Languages : Dutch (nla)
Descriptors: Indexation
2013-29 ; Biological Markers ; Cardiovascular diseases ; Decision Support Techniques ; Predictive Value of Tests ; R244
Classification
WG 141 -- Examination. Diagnosis. Diagnostic methods (General and heart specifically)Abstract: Artsen kunnen ons cardiovasculair risico bepalen met behulp van de SCORE-tabel. Daarmee kunnen ze op basis van ons tabaksgebruik, ons cholesterolgehalte en onze bloeddruk inschatten hoe hoog het risico is dat we binnen de 10 jaar overlijden aan een cardiovasculair incident. Het hulpmiddel is echter niet perfect. Daarom probeert men met bijkomende testen die atheromatose (in de volksmond aderverkalking genoemd) opsporen, de tabel nauwkeuriger te maken. Het Federaal Kenniscentrum voor de Gezondheidszorg (KCE) onderzocht de werkzaamheid van 6 van deze testen. Een aantal verbetert wel de « classificatie » van het risico, maar toch vonden de KCE-onderzoekers geen betrouwbaar bewijs dat hun toevoeging aan de SCORE-tabel de aanpak van mensen met een verhoogd risico verbetert.
Bijkomende, zeer eenvoudig te verkrijgen informatie over o.a. lichaamsbeweging, buikomtrek, sociaal statuut of vroegtijdige overlijdens in de familie door hartproblemen, kan de SCORE voorspelling wel aanzienlijk verbeteren. Het KCE beveelt daarom aan om een nieuwe SCORE-tabel te ontwikkelen waarin deze indicatoren, die gemakkelijk door de huisarts kunnen worden gebruikt, worden opgenomen.Link for e-copy: http://doi.org/10.57598/R244AS Format of e-copy: PDF (893 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3543 Copies(0)
Status No copy Nieuwe biochemische merkers van het risico op een eerste cardiovasculair incident / Dominique Roberfroid / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)
Nieuwe biochemische merkers van het risico op een eerste cardiovasculair incident : Synthese [printed text] / Dominique Roberfroid , Author ; Lorena San Miguel , Author ; Nancy Thiry, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2013 . - 14 p. : Ill. ; A4. - (KCE Reports A. Health Technology Assessment (HTA); 201As) .
ISSN : D/2013/10.273/19 : € 0,00
Studie 2011-21_HTA_Biomarkers
Languages : Dutch (nla)
Descriptors: Indexation
2011-21 ; Biological Markers ; Cardiovascular diseases ; Decision Support Techniques ; Predictive Value of Tests ; R201
Classification
WG 141 -- Examination. Diagnosis. Diagnostic methods (General and heart specifically)Link for e-copy: http://doi.org/10.57598/R201AS Format of e-copy: PDF (630 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3187 Copies(0)
Status No copy Non-invasive markers of subclinical atherosclerosis for predicting a primary cardiovascular event / Dominique Roberfroid / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2015)
Non-invasive markers of subclinical atherosclerosis for predicting a primary cardiovascular event : a rapid systematic review [printed text] / Dominique Roberfroid , Author ; Lorena San Miguel , Author ; Dominique Paulus , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2015 . - 45 p. : Ill., ; A4. - (KCE Reports. Health Technology Assessment (HTA); 244) .
ISSN : D/2015/10.273/43 : € 0,00
Study 2013-29_HTA_Risk_Markers_CVD
Languages : English (eng)
Descriptors: Indexation
2013-29 ; Biological Markers ; Cardiovascular diseases ; Decision Support Techniques ; Predictive Value of Tests ; R244
Classification
WG 141 -- Examination. Diagnosis. Diagnostic methods (General and heart specifically)Contents note: SCIENTIFIC REPORT 5 -- 1 BACKGROUND 5 -- 1.1 THE NEED FOR MORE ACCURATE PREDICTION 5 -- 1.2 USEFUL STATISTICS 8 -- 1.3 OBJECTIVES 8 -- 2 INCREMENTAL PREDICTIVE VALUE 10 -- 2.1 METHODS 10 -- 2.2 RESULTS 11 -- 2.2.1 Flow-mediated dilation 12 -- 2.2.2 Ankle-Brachial Index (ABI) 13 -- 2.2.3 Coronary artery calcification score (CAC) 19 -- 2.2.4 Carotid intima-media thickness (cIMT) 22 -- 2.2.5 Carotid plaques 24 -- 2.3 DISCUSSION 27 -- 3 CLINICAL BENEFIT OF IMPROVED RISK PREDICTION 28 -- 3.1 OBJECTIVES 28 -- 3.2 METHODS 28 -- 3.3 RESULTS 29 -- 3.4 DISCUSSION 29 -- 4 REVIEW OF EVIDENCE ON COST-EFFECTIVENESS 29 -- 4.1 METHODS 29 -- 4.1.1 Search strategy 29 -- 4.1.2 Selection procedure 30 -- 4.1.3 Selection criteria 30 -- 4.2 OVERVIEW OF ECONOMIC EVALUATIONS 31 -- 4.2.1 Type of economic evaluation 32 -- 4.2.2 Time frame of analyses and discounting 32 -- 4.2.3 Population 32 -- 4.2.4 Intervention and comparator 32 -- 4.2.5 Cost and outcome inputs 32 -- 4.2.6 Modelling 33 -- 4.2.7 Results 33 -- 4.2.8 Sensitivity analysis 35 -- 4.2.9 Conflict of interest 35 -- 4.2.10 Discussion 35 -- 4.2.11 Conclusion 36 -- 5 DISCUSSION 36 -- BIBLIOGRAPHY 39 Link for e-copy: http://doi.org/10.57598/R244C Format of e-copy: PDF (511 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3539 Copies(0)
Status No copy Non-invasive markers of subclinical atherosclerosis for predicting a primary cardiovascular event / Dominique Roberfroid / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2015)
Non-invasive markers of subclinical atherosclerosis for predicting a primary cardiovascular event : a rapid systematic review - Appendix [printed text] / Dominique Roberfroid , Author ; Lorena San Miguel , Author ; Dominique Paulus , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2015 . - 32 p. : Ill., ; A4. - (KCE Reports. Health Technology Assessment (HTA); 244S) .
ISSN : D/2015/10.273/44 : € 0,00
Study 2013-29_HTA_Risk_Markers_CVD
Languages : English (eng)
Descriptors: Indexation
2013-29 ; Biological Markers ; Cardiovascular diseases ; Decision Support Techniques ; Predictive Value of Tests ; R244
Classification
WG 141 -- Examination. Diagnosis. Diagnostic methods (General and heart specifically)Contents note: 1 SEARCH STRATEGY – CLINICAL REVIEW 2 -- 1.1 MEDLINE @ PUBMED 2 -- 1.2 EMBASE 3 -- 1.3 COCHRANE DATABASE OF SYSTEMATIC REVIEWS 5 -- DARE 1.4 AND HTA DATABASE (CRD) 6 -- 2 QUALITY APPRAISAL – CLINICAL EVIDENCE 7 -- 2.1 PETERS 2012 7 -- 2.1.1. Amstar: Peters 20121 8 -- 2.2 LIN 2013 9 -- 2.2.1. AMSTAR: LIN 2013 2 10 -- 2.3 BEN SHLOMO 2014 11 -- 2.3.1. AMSTAR BEN-SHLOMO 2014 3 12 -- 2.4 FOWKES 2014 13 -- 2.5 DEN RUITJER 2012 15 -- 2.6 YEBOAH 2012 18 -- 2.7 MÖHLENKAMP 2011 19 -- 2.8 KAVOUSI 2012 20 -- 2.9 PEREIRA 2014 21 -- 2.10 POLLAK 2011 23 -- 2.11 POLLAK 2013 24 -- 3 SEARCH STRATEGY – ECONOMIC REVIEW 26 -- 3.1 MEDLINE (OVID) 26 -- 3.2 EMBASE 28 -- 3.3 NHSEED & NHSHTA (CRD) 30 -- 3.4 ECONLIT 30 -- 4 FLOW CHART SELECTION - ECONOMIC EVALUATIONS 31 Link for e-copy: http://doi.org/10.57598/R244S Format of e-copy: PDF (382 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3541 Copies(0)
Status No copy Non-invasive markers of subclinical atherosclerosis for predicting a primary cardiovascular event / Dominique Roberfroid / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2015)
PermalinkNouveaux biomarqueurs pour estimer le risque cardiovasculaire / Dominique Roberfroid / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)
PermalinkNovel serum biomarkers fot the prediction of cardiovascular risk / Dominique Roberfroid / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)
PermalinkNovel serum biomarkers fot the prediction of cardiovascular risk / Dominique Roberfroid / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)
PermalinkThe significance of activation markers on CD8 lymphocytes in human immunodeficiency syndrome: staging and prognostic value / M. Levacher in Clinical and experimental immunology, 90(1992)3 ([12/01/1992])
PermalinkUtilité des marqueurs d’athérosclérose dans la prédiction du risque d’accident cardiovasculaire / Dominique Roberfroid / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2015)
Permalink