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Age-related changes in human blood lymphocyte subpopulations / F. Erkeller-Yuksel in The Journal of Pediatrics, 120(1996)2 ([02/01/1996])  

[article] Age-related changes in human blood lymphocyte subpopulations [printed text] / F. Erkeller-Yuksel, Author ; V. Deneys, Author ; B. Yuksel, Author ; I. Hannet, Author ; Frank Hulstaert, Author ; C. Hamilton, Author . - 1996 . - 216-222. Languages : English (eng) in The Journal of Pediatrics > 120(1996)2 [02/01/1996] . - 216-222 Descriptors: Classification W 1 Serials. Periodicals Indexation Adolescent ; Adult ; Aged ; Aging ; Antigens, CD ; Child ; Child, Preschool ; Female ; Fetal Blood ; Humans ; Immunophenotyping ; Infant ; Journal Article ; Leukocyte Count ; Lymphocyte Subsets ; Male ; Middle Aged ; Peer Review ; United States Abstract: Flow cytometric analysis of major lymphocyte populations and their subsets reveals age-related changes in the cellular human immune system. Immunophenotypic markers were evaluated in 110 normal pediatric subjects, divided into groups of newborn infants, infants aged 2 days to 11 months, and children aged 1 to 6 years and 7 to 17 years; results were then compared with those obtained from 101 normal adults aged 18 to 70 years. Comparisons among age groups from newborn infants through adults reveal progressive declines in the absolute numbers of leukocytes, total lymphocytes, and T, B, and natural killer (NK) cells. The percentages of T cells within the total lymphocyte population increase with age, in both CD4+ and CD8+ subsets. Percentages of B and NK cells are higher in newborn infants than in adults. The expression of the activation markers interleukin-2R and HLA-DR on T cells increases with age, as does the NK-associated expression of CD57 on CD8 cells. The proportions of B lymphocytes that coexpress CD5 or CDw78 decrease with age, whereas expression of Leu-8 and CD23 increases. The proportion of CD4 cells bearing the CD45RA and Leu-8 markers is consistently lower in adults than in children. These data may serve as a reference range for studies of pediatric subjects. Link for e-copy: http://www.sciencedirect.com/science/journal/00223476 Format of e-copy: PDF [Requires Subscription] Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=2187 [article]

Age-related changes in human blood lymphocyte subpopulations / Frank Hulstaert in Clinical immunology and immunopathology, 70(1994)02 ([02/01/1994])  

[article] Age-related changes in human blood lymphocyte subpopulations : II. Varying Kinetics of Percentage and Absolute Count Measurements [printed text] / Frank Hulstaert, Author ; I. Hannet, Author ; V. Deneys, Author ; V. Munhyeshuli, Author ; T. Reichert, Author ; M. De Bruyere, Author ; K. Strauss, Author . - 1994 . - 152-158. Languages : English (eng) in Clinical immunology and immunopathology > 70(1994)02 [02/01/1994] . - 152-158 Descriptors: Classification W 1 Serials. Periodicals Indexation Adolescent ; Adult ; Aging ; Antigens, CD ; Antigens, Differentiation ; Child ; Child, Preschool ; Female ; Humans ; Immunophenotyping ; Infant ; Infant, Newborn ; Journal Article ; Leukocyte Count ; Male ; Middle Aged ; T-Lymphocytes ; United States Abstract: A reference range for lymphocyte populations, with particular emphasis on T lymphocyte subsets, was obtained for normal individuals covering age cohorts from birth through adulthood. This report confirms and extends findings from a developmental reference range published earlier (1). Absolute numbers of WBC, lymphocytes, and T, B, and NK subsets decline significantly during childhood. However, differences in the rate of decline of certain lymphocyte subsets leads to discordance between absolute numbers and percentages. Those lymphocyte subsets which decline less rapidly with age than the total lymphocyte count will show an increase in percentage, whereas those which decline more rapidly will show further declines in percentage values. T cell percentages were seen to increase over time whereas B cell percentages decline. Markers of immaturity such as CD45RA on CD4 cells and CD38 on CD8 cells declined in both percentages and absolute numbers. Activation markers, such as HLA-DR on CD8 cells and IL2-R on CD3 cells, increased in percentages with time but changed inconsistently in cell number from infancy to adulthood. These findings extend the lymphocyte references range to markers thought to be informative in various disease states, including HIV infection. Link for e-copy: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WCK-45R79S2-9&_user=1 [...] Format of e-copy: VDIC IP recognition Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=2209 [article]

An economic evaluation of varicella vaccination in Italian adolescents / Nancy Thiry in Vaccine, 22(2004)27-28 ([09/09/2004])  

[article] An economic evaluation of varicella vaccination in Italian adolescents [printed text] / Nancy Thiry, Author ; Philippe Beutels, Author ; Francesco Tancredi, Author ; A. Zanetti, Author ; Paolo Bonanni, Author ; Giovanni Gabutti, Author ; Pierre Van Damme, Author . - 2004 . - 3546-3562. Languages : English (eng) in Vaccine > 22(2004)27-28 [09/09/2004] . - 3546-3562 Descriptors: Classification W 1 Serials. Periodicals Indexation Adolescent ; Adult ; Age Factors ; Aged ; Chickenpox Vaccine ; Child ; Child, Preschool ; Cost of Illness ; Cost-Benefit Analysis ; Economics ; Encephalitis, Varicella Zoster ; Epidemiology ; Female ; Hospitalization ; Humans ; Italy ; Journal Article ; Male ; Markov Chains ; Mass Immunization ; Middle Aged ; Netherlands ; Peer Review ; prevention and control ; statistics and numerical data [Subheading] Abstract: An economic evaluation was performed to assess five varicella vaccination scenarios targeted to 11-year-old Italian adolescents. The scenarios were: "compulsory vaccination" of all adolescents, recommended vaccination of susceptible adolescents on the basis of an "anamnestic screening", a "blood test" or a combination of both ("both tests") and vaccination of adolescents in the private sector, at the parents' charge ("private vaccination"). Probabilities and unit costs were taken from published sources and experts opinion. The accuracy of the anamnestic screening (81.6% sensitivity and 87.3% specificity) was derived from a separate descriptive study among 344 Italian adolescents. The costs and benefits of each scenario were simulated using a Markov model and cost-effectiveness, budget-impact and cost-benefit analyses were conducted. Of all considered scenarios, "both tests" and "anamnestic screening" were the most appealing options with an estimated net direct cost of 5058 and 8929 per life-year gained (compared to no vaccination) versus 14,693-42,842 for the other scenarios. These two scenarios further resulted in substantial net savings for society (over 600,000 per cohort, BCR: 2.17). The need for a serological confirmation was highly dependent on the sensitivity of the anamnestic screening, which is believed to increase once such a program is launched. For practical considerations, "anamnestic screening" seems to be the most convenient option. Link for e-copy: http://tiny.cc/xktyn Format of e-copy: VDIC IP recognition Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=1773 [article]

L'attachement / Nicole Guedeney / Issy les Moulineaux [France] : Elsevier|Masson (2016)

L'attachement : Approche théorique - du bébé à la personne âgée [printed text] / Nicole Guedeney, Author ; Antoine Guedeney, Author . - Issy les Moulineaux [France] : Elsevier|Masson, 2016 . - 335 p. : ill., ; A5. ISBN : 978-2-294-74520-1 : € 35,00 Languages : French (fre) Descriptors: Classification WM 34 Handbooks. Resource guides Indexation Child, Preschool ; Family Relations ; Infant, Newborn ; Pediatrics ; Psychopathology Abstract: La théorie de l'attachement propose une compréhension de la genèse du lien fondamental tel qu'un bébé s'attache à ceux qui l'élèvent. Le moteur essentiel de cette construction est la satisfaction de son besoin inné de proximité et de sécurité avec les figures censées le protéger. Cet ouvrage présente les concepts généraux de la théorie de l'attachement tout au long de la vie, de la naissance à l'âge mûr. Cette 4e édition propose une mise à jour complète de l'ensemble des connaissances sur la théorie de l'attachement, dont les applications thérapeutiques se développent. Elle propose également des thématiques nouvelles liées aux découvertes récentes en neurosciences et à l'évolution de la société : Attachement et neurosciences - Attachement et courant développemental chez l'adulte - Attachement et sexualité de l'adulte - Attachement et société - Les mesures de l'attachement chez l'adolescent et la personne âgée. Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3908

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Convincing or confusing? / Philippe Beutels in Vaccine, 25(2007)8 ([02/09/2007])  

[article] Convincing or confusing? : Economic evaluations of childhood pneumococcal conjugate vaccination [printed text] / Philippe Beutels, Author ; Nancy Thiry, Author ; Pierre Van Damme, Author . - 2007 . - 1355-1367. Research Support, Non-U.S. Gov't Review Languages : English (eng) in Vaccine > 25(2007)8 [02/09/2007] . - 1355-1367 Descriptors: Classification W 1 Serials. Periodicals Indexation Child, Preschool ; Economics ; Humans ; immunology ; Infant ; Journal Article ; Netherlands ; Peer Review ; Pneumococcal Infections ; Pneumococcal Vaccines ; prevention and control ; Vaccines Conjugate Abstract: We review 15 economic analyses of pneumococcal conjugate vaccines, published between 2002 and 2006, in terms of methodology, assumptions, results and conclusions. We found a great diversity in assumptions (eg, vaccine efficacy parameters, incidence rates for both invasive and non-invasive disease) mainly due to local variation in data and opinions. Accordingly, the results varied greatly, from total net savings to over euro 100,000 per discounted QALY gained. The cost of the vaccination program (determined by price per dose and schedule (4 or 3 doses, or fewer)), and likely herd immunity impacts are highly influential though rarely explored in these published studies. If the net long-term impact (determined by a mixture of effects related to herd immunity, serotype replacement, antibiotic resistance and cross reactivity) remains beneficial and if a 3-dose schedule confers near-equivalent protection to a 4-dose schedule, the cost-effectiveness of PCV7 vaccination programs can be viewed as attractive in developed countries. Link for e-copy: http://tiny.cc/aalwe Format of e-copy: VDIC IP recognition Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=1767 [article]

Dental attendance in preschool children / Roos Leroy in International journal of paediatric dentistry, 23(2013)02 ([03/01/2013])  

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Economic evaluations of varicella vaccination programmes / Nancy Thiry in Pharmacoeconomics, 21(2003)1 ([01/01/2003])  

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Effects of time and socio-economic status on the determinants of oral health-related behaviours of parents of preschool children / Sigrid Van den Branden in European Journal of Oral Sciences, 120(2012)02 ([04/01/2012])  

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Ernstige infecties bij kinderen op een spoedgevallendienst in Vlaanderen / Ann Van den Bruel in Tijdschrift voor geneeskunde, 63(2007)08 ([04/15/2007])  

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Invasive Haemophilus influenzae Disease, Europe, 1996-2006 / S. Ladhani in Emerging Infectious Diseases, 16(2010)03 ([03/01/2010])  

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Iron supplementation in previously anemic Bolivian children normalized hematologic parameters, but not immunologic parameters. / E. Sejas in Journal of Tropical Pediatrics, 54(2008)3 ([06/02/2008])  

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Is the 2000 CDC growth reference appropriate for developing countries? / Dominique Roberfroid in Public Health Nutrition, 9(2006)2 ([04/01/2006])  

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Management of malnutrition in preschool children: the role of primary health care services / T. Hoeree in Santé, 12(2002)1 ([01/01/2002])  

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Measuring appropriate use of antibiotics in pyelonephritis in Belgian hospitals / Cécile Camberlin in Computer methods and programs in biomedicine, 94(2009)2 ([05/01/2009])  

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Measuring the body temperature / Ann Van den Bruel in Technology and health care, 13(2005)2 ([03/01/2005])  

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