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Classification > W - MEDICINE > WI - DIGESTIVE SYSTEM > WI 810 Pancreas - Neoplasms. Cysts
WI 810 Pancreas - Neoplasms. Cysts |
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Aanpak van pancreaskanker / Geneviève Veereman / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2017)
Aanpak van pancreaskanker : capita selecta – Samenvatting [printed text] / Geneviève Veereman, Author ; Marc Peeters, Author ; Nadia Haj Mohammad, Author ; Maarten Van Leeuwen, Author ; Rob Scholten, Author ; Hans Van Brabandt , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2017 . - 8 p. : ill., ; A4. - (KCE Reports A. Good Clinical Practice (GCP); 286AS) .
ISSN : D/2017/10.273/26 : € 0,00
Studie 2015-03
Languages : Dutch (nla)
Descriptors: Indexation
2015-03 ; Pancreatic Neoplasms ; Practice Guideline [Publication type] ; R286
Classification
WI 810 Pancreas - Neoplasms. CystsAbstract: Pancreaskanker is een ernstige kanker die vooral mensen boven de 60 jaar treft, en die in ons land en in andere westerse landen steeds meer voorkomt. Het Federaal Kenniscentrum voor de Gezondheidszorg (KCE) en het College voor Oncologie publiceren vandaag een selectieve update van hun klinische richtlijn van 2009 over de diagnose en behandeling van deze kanker. De aanbevelingen in de richtlijn zijn gebaseerd op de meest recente wetenschappelijke gegevens, en werden geformuleerd in overleg met een groot aantal artsen en vertegenwoordigers van patiënten. Contents note: VOORWOORD 1 -- SAMENVATTING 2 -- 1. INLEIDING EN SCOPE 3 -- 2. DOELGROEP 4 -- 3. METHODOLOGIE 4 -- 3.1. SYSTEMATISCHE EVALUATIE VAN DE LITERATUUR 4 -- 3.2. VOORKEUREN VAN DE PATIËNT 5 -- 3.3. FORMULERING VAN AANBEVELINGEN 5 -- 4. KLINISCHE AANBEVELINGEN 6 -- 4.1. DIAGNOSE VAN PANCREASKANKER 6 -- 4.2. NEOADJUVANTE THERAPIE BIJ PANCREASKANKER 7 -- 4.3. GERECIDIVEERDE EN GEMETASTASEERDE PANCREASKANKER 8 -- 4.4. IMPLEMENTATIE EN UPDATE VAN DEZE RICHTLIJN 8 -- 4.4.1. Multidisciplinaire, patiënt-gerichte, benadering 8 -- 4.4.2. Bewaking van de zorgkwaliteit 8 -- 4.4.3. Update van richtlijn en onderzoeksagenda 8 Link for e-copy: https://doi.org/10.57598/R286AS Format of e-copy: PDF (441 KB) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4175 Management of pancreatic cancer: capita selecta / Geneviève Veereman / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2017)
Management of pancreatic cancer: capita selecta : – Part 1: Introduction and methodology [printed text] / Geneviève Veereman, Author ; Marc Peeters, Author ; Nadia Haj Mohammad, Author ; Maarten Van Leeuwen, Author ; Rob Scholten, Author ; Hans Van Brabandt , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2017 . - 39 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 286C1) .
ISSN : D/2017/10.273/29 : € 0,00
Study 2015-03
Languages : English (eng)
Descriptors: Indexation
2015-03 ; Pancreatic Neoplasms ; Practice Guideline [Publication type] ; R286
Classification
WI 810 Pancreas - Neoplasms. CystsContents note: SCIENTIFIC REPORT 6 -- 1 INTRODUCTION 6 -- 1.1 BACKGROUND 6 -- 1.2 THE NEED FOR A GUIDELINE 10 -- 1.3 SCOPE 11 -- 1.4 REMIT OF THE GUIDELINE 12 -- 1.4.1 Overall objectives 12 -- 1.4.2 Target users of the guideline 12 -- 1.5 STATEMENT OF INTENT 12 -- 1.6 FUNDING AND DECLARATION OF INTEREST 13 -- 2 GENERAL METHODOLOGY 13 -- 2.1 INTRODUCTION 13 -- 2.2 THE GUIDELINE DEVELOPMENT GROUP 13 -- 2.3 GENERAL APPROACH AND RESEARCH QUESTIONS 14 -- 2.3.1 RQs, PIRT and PICOs 14 -- 2.4 LITERATURE SEARCH 15 -- 2.5 SELECTION PROCESS 15 -- 2.6 QUALITY APPRAISAL 15 -- 2.6.1 Systematic reviews 15 -- 2.6.2 Primary studies 15 -- 2.7 DATA EXTRACTION AND EVIDENCE SUMMARY 16 -- 2.8 STATISTICAL ANALYSIS 16 -- 2.9 GRADING EVIDENCE 16 -- 2.10 LITERATURE SEARCH FOR PATIENT PREFERENCES 17 -- 2.11 FORMULATION OF RECOMMENDATIONS 17 -- 2.12 EXTERNAL REVIEW 18 -- 2.12.1 Healthcare professionals 18 -- 2.12.2 Patient representatives 18 -- 2.12.3 Final validation 18 -- 2.13 IMPLEMENTATION AND UPDATING OF THE GUIDELINE 18 -- 2.13.1 Multidisciplinary approach 18 -- 2.13.2 Patient-centered care 18 -- 2.13.3 Barriers and facilitators for implementation 18 -- 2.13.4 Actors of the implementation of this guideline 18 -- 2.13.5 Monitoring the quality of care 19 -- 2.13.6 Guideline update 19 -- 3 APPENDIX 20 -- 3.1 UIAC TNM CLASSIFICATION 20 -- 3.2 SCOPING 22 -- 3.3 CRITICAL APPRAISAL CHECKLISTS FOR SYSTEMATIC REVIEWS AND PRIMARY STUDIES 29 -- 3.3.1 Systematic reviews 29 -- 3.3.2 Diagnostic accuracy studies31 -- 3.3.3 Primary studies for therapeutic interventions 32 -- 3.4 GRADING EVIDENCE 33 -- 3.5 FORMULATION OF RECOMMENDATIONS 35 -- 3.5.1 Evaluation of the recommendations 35 -- 3.5.2 Stakeholder meeting 36 -- REFERENCES 37 Link for e-copy: https://doi.org/10.57598/R286C1 Format of e-copy: PDF (632 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4171 Management of pancreatic cancer / Geneviève Veereman / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2017)
Management of pancreatic cancer : – Part 2: Diagnosis [printed text] / Geneviève Veereman, Author ; Marc Peeters, Author ; Nadia Haj Mohammad, Author ; Maarten Van Leeuwen, Author ; Rob Scholten, Author ; Hans Van Brabandt , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2017 . - 50 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 286C2) .
ISSN : D/2017/10.273/30 : € 0,00
Study 2015-03
Languages : English (eng)
Descriptors: Indexation
2015-03 ; Pancreatic Neoplasms ; Practice Guideline [Publication type] ; R286
Classification
WI 810 Pancreas - Neoplasms. CystsContents note: SCIENTIFIC REPORT 5 -- 1 INTRODUCTION 5 -- 2 STUDY IDENTIFICATION AND SELECTION 7 -- 3 EVIDENCE DESCRIPTION 8 -- 3.1 IMAGING TESTS TO DIAGNOSE MALIGNANT PANCREATIC LESIONS 8 -- 3.1.1 Differentiating between cancerous and benign lesions 8 -- 3.1.2 Differentiating between precancerous or cancerous and benign lesions 8 -- 3.2 SERUM TUMOUR MARKERS IN THE DIAGNOSTIC WORK-UP OF PANCREATIC LESIONS 8 -- 3.2.1 Carbohydrate antigen 19-9 (CA 19-9) 8 -- 3.2.2 Carcino Embryonal Antigen (CEA) 9 -- 3.3 TESTS TO ASSESS CURATIVE RESECTABILITY OF PANCREATIC CANCER 10 -- 3.3.1 Laparoscopy 10 -- 3.3.2 EUS 10 -- 4 CONCLUSIONS,OTHER CONSIDERATIONS AND RECOMMENDATIONS 11 -- 4.1 CONCLUSIONS 11 -- 4.2 OTHER CONSIDERATIONS 11 -- 4.3 RECOMMENDATIONS 12 -- 5 APPENDIX 13 -- 5.1 SEARCH STRATEGY 13 -- 5.2 STUDY SELECTION 18 -- 5.3 CRITICAL APPRAISAL 24 -- 5.4 EVIDENCE TABLES 26 -- 5.5 GRADE TABLES 37 -- 5.6 STAKEHOLDER MEETING 42 -- REFERENCES 44 Link for e-copy: https://doi.org/10.57598/R286C2 Format of e-copy: PDF (1,6 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4172 Management of pancreatic cancer / Geneviève Veereman / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2017)
Management of pancreatic cancer : – Part 3: neoadjuvant and induction therapy [printed text] / Geneviève Veereman, Author ; Marc Peeters, Author ; Nadia Haj Mohammad, Author ; Maarten Van Leeuwen, Author ; Rob Scholten, Author ; Hans Van Brabandt , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2017 . - 84 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 286C3) .
ISSN : D/2017/10.273/31 : € 0,00
Study 2015-03
Languages : English (eng)
Descriptors: Indexation
2015-03 ; Pancreatic Neoplasms ; Practice Guideline [Publication type] ; R286
Classification
WI 810 Pancreas - Neoplasms. CystsContents note: SCIENTIFIC REPORT 5 -- 1 INTRODUCTION 5 -- 2 SELECTING STUDIES AND QUALITY APPRAISAL 6 -- 2.1 SELECTION OF SYSTEMATIC REVIEWS 6 -- 2.2 SELECTION OF PRIMARY STUDIES 9 -- 2.3 ASSESSMENT OF RISK OF BIAS 11 -- 3 EVIDENCE DESCRIPTION 11 -- 3.1 RQA: WHAT IS THE CLINICAL EFFECTIVENESS OF NEOADJUVANT TREATMENT WITH CHEMOTHERAPY, RADIOTHERAPY OR BOTH, FOLLOWED BY SURGERY IN PATIENTS WITH RESECTABLE PC? 11 -- 3.1.1 Neoadjuvant chemoradiotherapy followed by surgery vs upfront surgery 11 -- 3.1.2 Neoadjuvant chemotherapy vs another type of neoadjuvant chemotherapy (both followed by surgery) 14 -- 3.2 RQB: WHAT IS THE EFFECT OF NEOADJUVANT TREATMENT WITH CHEMOTHERAPY, RADIOTHERAPY OR BOTH, FOLLOWED BY SURGERY IN PATIENTS WITH BORDERLINE RESECTABLE PC? 14 -- 3.2.1 Neoadjuvant chemo(radio)therapy followed by surgery vs upfront surgery 14 -- 3.3 RQC: FOR PATIENTS DIAGNOSED WITH LAPC, DOES INDUCTION TREATMENT WITH CHEMOTHERAPY, RADIOTHERAPY OR BOTH, LEAD TO SURGERY AND IS IT ASSOCIATED WITH BETTER SURVIVAL, RESECTABILITY, QOL AND COMPLICATION RATE COMPARED TO ANY OTHER TYPE OF TREATMENT? 15 -- 3.3.1 Induction chemotherapy versus another type of induction chemotherapy 15 -- 3.3.2 Induction chemoradiotherapy versus induction chemotherapy 15 -- 3.3.3 Induction chemoradiotherapy versus another type of induction chemoradiotherapy 16 -- 4 CONCLUSIONS, OTHER CONSIDERATIONS AND RECOMMENDATIONS 18 -- 4.1 CONCLUSIONS 18 -- 4.2 OTHER CONSIDERATIONS 20 -- 4.3 RECOMMENDATIONS 21 -- 5 APPENDIX 22 -- 5.1 STUDY SELECTION 22 -- 5.2 CRITICAL APPRAISAL 27 -- 5.3 EVIDENCE TABLES 39 -- 5.3.1 Evidence tables of RCTs regarding the effect of neoadjuvant treatment with chemo therapy, radiotherapy or both, followed by surgery in patients with resectable PC (RQa) 39 -- 5.3.2 Evidence tables of comparative observational studies regarding the effect of neoadjuvant treatment with chemotherapy, radiotherapy or both, followed by surgery in patients with borderline resectable PC (RQb) 46 -- 5.3.3 Evidence tables of RCTs regarding the effect of neoadjuvant (induction) treatment with chemotherapy, radiotherapy or both, followed by surgery in patients with LAPC (RQc) 48 -- 5.4 GRADE EVIDENCE PROFILES 61 -- 5.5 STAKEHOLDER MEETING 75 -- REFERENCES 77 Link for e-copy: https://doi.org/10.57598/R286C3 Format of e-copy: PDF (2,8 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4173 Management of pancreatic cancer / Geneviève Veereman / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2017)
Management of pancreatic cancer : – Part 4: recurrent and metastatic cancer [printed text] / Geneviève Veereman, Author ; Marc Peeters, Author ; Nadia Haj Mohammad, Author ; Maarten Van Leeuwen, Author ; Rob Scholten, Author ; Hans Van Brabandt , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2017 . - 40 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 286C4) .
ISSN : D/2017/10.273/32 : € 0,00
Study 2015-03
Languages : English (eng)
Descriptors: Indexation
2015-03 ; Pancreatic Neoplasms ; Practice Guideline [Publication type] ; R286
Classification
WI 810 Pancreas - Neoplasms. CystsContents note: SCIENTIFIC REPORT 5 -- 1 INTRODUCTION 5 -- 2 SELECTING STUDIES AND QUALITY APPRAISAL 6 -- 2.1 SELECTION OF SYSTEMATIC REVIEWS 6 -- 2.2 SELECTION OF PRIMARY STUDIES 7 -- 2.3 ASSESSMENT OF RISK OF BIAS .7 -- 2.3.1 Systematic reviews 7 -- 2.3.2 Primary studies 7 -- 3 EVIDENCE DESCRIPTION 8 -- 3.1 WHAT IS THE OPTIMAL TREATMENT STRATEGY IN PATIENTS WITH RECURRENT/ METASTATIC PANCREATIC CANCER? 8 -- 3.1.1 Anticancer therapy vs best supportive care .8 -- 3.1.2 Various types of chemotherapy vs gemcitabine 9 -- 3.1.3 Gemcitabine combinations versus gemcitabine alone .12 -- 3.1.4 Fluoropyrimidine combinations versus fluoropyrimidine alone 15 -- 3.1.5 Radiation therapy or chemoradiation therapy 16 -- 3.1.6 Re-resection vs best supportive care, including palliative care 16 -- 4 CONCLUSIONS, OTHER CONSIDE-RATIONS AND RECOMMENDATIONS 17 -- 4.1 CONCLUSIONS .17 -- 4.2 OTHER CONSIDERATIONS 18 -- 4.3 RECOMMENDATIONS 18 -- 5 APPENDIX 19 -- 5.1 STUDY SELECTION 19 -- 5.2 CRITICAL APPRAISAL 22 -- 5.3 EVIDENCE TABLES 22 -- 5.4 GRADE EVIDENCE PROFILES 27 -- 5.5 STAKEHOLDER MEETING .34 -- REFERENCES 35 Link for e-copy: https://doi.org/10.57598/R286C4 Format of e-copy: PDF (1,7 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4174 Prise en charge du cancer du pancréas / Geneviève Veereman / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2017)
PermalinkSoutien scientifique au Collège d’Oncologie / Marc Peeters ; Joan Vlayen ; Sabine Stordeur ; Françoise Mambourg ; Tom Boterberg ; Bernard de Hemptinne ; Pieter Demetter ; Pierre Deprez ; Jean-François Gigot ; Anne Hoorens ; Eric Van Cutsem ; Bart Van den Eynden ; Jean-Luc Van Laethem / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2009)
PermalinkWetenschappelijke ondersteuning van het College voor Oncologie / Marc Peeters ; Joan Vlayen ; Sabine Stordeur ; Françoise Mambourg ; Tom Boterberg ; Bernard de Hemptinne ; Pieter Demetter ; Pierre Deprez ; Jean-François Gigot ; Anne Hoorens ; Eric Van Cutsem ; Bart Van den Eynden ; Jean-Luc Van Laethem / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2009)
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