[article] A comparative study of European rare disease and orphan drug markets [printed text] / Alain Denis, Author ; Lut Mergaert, Author ; Christel Fostier, Author ; Irina Cleemput  , Author ; Simoens, Steven, Author . - 2010 . - p. 173-179. Languages : English ( eng) in Health Policy > 97(2010)2-3 [10/01/2010] . - p. 173-179
| Descriptors: |
Classification
W 1 Serials. Periodicals
Indexation
Cost Control ; Drug and Narcotic Control ; Drug Costs ; Europe ; Fees, Pharmaceutical ; Health Policy ; Insurance, Health, Reimbursement ; Journal Article ; legislation and jurisprudence ; Marketing ; Orphan Drug Production ; Peer Review
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| Abstract: |
OBJECTIVES: This article aims to compare regulatory aspects of rare disease and orphan drug markets in Belgium, France, Italy, the Netherlands, Sweden and the United Kingdom. METHODS: Information was derived from the international literature, analysis of legal texts, and a survey completed by national experts. RESULTS: These countries adopted varying approaches towards regulating rare disease and orphan drug markets and, hence, the availability, pricing and reimbursement of orphan drugs vary between countries. Strategies to keep down prices include public procurement in Sweden, profit controls in the United Kingdom, and price comparisons with other countries. To gain reimbursement, the cost-effectiveness and/or budget impact of orphan drugs is considered in some countries. Other societal considerations, such as whether the drug treats a life-threatening disease, are sometimes taken into account. CONCLUSIONS: Extensive government intervention exists in rare disease and orphan drug markets in the countries studied. Our recommendations are to define priorities for research on rare diseases and orphan drugs at the European level, to set up disease and patient registries with a view to investigating the long-term effectiveness and cost-effectiveness of orphan drugs, to assess the profitability of orphan drugs, and to take into account societal considerations when evaluating orphan drugs. |
| Link for e-copy: |
https://doi.org/10.1016/j.healthpol.2010.05.017 |
| Format of e-copy: |
PDF [Requires Subscription] |
| Record link: |
https://kce.docressources.info/index.php?lvl=notice_display&id=4095 |
[article]
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Add the result to your basket Make a suggestion Refine your search Apply to external sourcesA comparative study of European rare disease and orphan drug markets in Health Policy, 97(2010)2-3 ([10/01/2010])
Construction d’un index médical pour les contrats privés d’assurance maladie. / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2008)
