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Analytical performance and clinical utility of the INNOTEST PHOSPHO-TAU181P assay for discrimination between Alzheimer's disease and dementia with Lewy bodies. / H. Vanderstichele in Clinical chemistry and laboratory medicine, 44(2006)12 ([01/01/2006])
[article] Analytical performance and clinical utility of the INNOTEST PHOSPHO-TAU181P assay for discrimination between Alzheimer's disease and dementia with Lewy bodies. [printed text] / H. Vanderstichele, Author ; K. De Vreese, Author ; K. Blennow, Author ; N. Andreasen, Author ; C. Sindic, Author ; A. Ivanoiu, Author ; H. Hampel, Author ; K. Burger, Author ; L. Parnetti, Author ; A. Padovani, Author ; M. Di Luca, Author ; M. Blaser, Author ; A.O. Olsson, Author ; H. Pottel, Author ; Frank Hulstaert, Author ; E. Vanmechelen, Author . - 2006.
Languages : English (eng)
in Clinical chemistry and laboratory medicine > 44(2006)12 [01/01/2006]
Descriptors: Classification
W 1 Serials. Periodicals
Indexation
Aged ; Alzheimer Disease ; Amyloid beta-Peptides ; Biological Markers ; Diagnosis, Differential ; Discriminant Analysis ; Enzyme-Linked Immunosorbent Assay ; Female ; Germany ; Humans ; Journal Article ; Lewy Body Disease ; Logistic Models ; Male ; Middle Aged ; Peer Review ; Peptide Fragments ; Reproducibility of Results ; Sensitivity and specificityAbstract: BACKGROUND: Total tau (T-tau) and beta-amyloid((1-42)) (Abeta(1-42)) levels in cerebrospinal fluid (CSF) can differentiate Alzheimer's disease (AD) from normal aging or depressive pseudo-dementia. Differential diagnosis from dementia with Lewy bodies (DLB) in clinical settings is difficult.
METHODS: The analytical performance of the INNOTEST PHOSPHO-TAU(181P) assay was validated in terms of selectivity, sensitivity, specificity, precision, robustness, and stability. Clinical utility of the assay alone, or combined with T-tau and Abeta(1-42), for discrimination of AD (n=94) from patients suffering from DLB (n=60) or from age-matched control subjects (CS) (n=60) was assessed in a multicenter study.
RESULTS: CSF concentrations of tau phosphorylated at threonine 181 (P-tau(181P)) in AD was significantly higher than in DLB and CS. Discriminant analysis, a classification tree, and logistic regression showed that P-tau(181P) was the most statistically significant single variable of the three biomarkers for discrimination between AD and DLB.
CONCLUSIONS: P-tau(181P) quantification is a robust and reliable assay that may be useful in discriminating AD from DLB.Link for e-copy: http://dx.doi.org/10.1515/CCLM.2006.258 Format of e-copy: PDF [Requires Subscription] Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=2205 [article]Animation techniques for better patient involvement / Marie Dauvrin / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2021)
Animation techniques for better patient involvement : Patient involvement - KCE process book [printed text] / Marie Dauvrin , Author ; Laurence Kohn , Author ; Irina Cleemput , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2021 . - 39 p. : ill., ; A4.
ISSN : D/2020/10.2733/25 : € 0,00
Languages : English (eng)
Descriptors: Indexation
Methods ; Patient Participation
Classification
W 49 Handbooks. Resource guidesLink for e-copy: https://doi.org/10.57598/R340 Format of e-copy: PDF (1,02 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4757 Ankle sprains / Philip Roosen / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)
Ankle sprains : diagnosis and therapy [printed text] / Philip Roosen, Author ; Tine Willems, Author ; Roel De Ridder, Author ; Lorena San Miguel , Author ; Kirsten Holdt Henningsen, Author ; Dominique Paulus , Author ; An De Sutter, Author ; Pascale Jonckheer , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2013 . - 158 p. : Ill. ; A4. - (KCE Reports. Good Clinical Practice (GCP); 197C) .
ISSN : D/2013/10.273/4 : € 0,00
Study n° : 2011-02
Languages : English (eng)
Descriptors: Indexation
2011-02 ; Ankle Injuries ; Diagnosis ; Practice Guideline [Publication type] ; R197 ; Therapeutics
Classification
WE 880 Ankle. FootContents note: SCIENTIFIC REPORT 7 -- 1 -- INTRODUCTION 7 -- 1.1 ANKLE SPRAIN: A FREQUENT PROBLEM 7 -- 1.2 CONTROVERSIES ON THE N EED FOR RADIOGRAPHY 7 -- 1.3 OBJECTIVE OF THIS REPORT 8 -- 1.4 ANATOMY AND CLASSIFICATION OF ANKLE SPRAINS 8 -- 1.4.1 Anatomy of the ankle 8 -- 1.4.2 Ligaments hit in ankle sprains . 8 -- 1.4.3 Classification of ankle sprains .. 9 -- 2 SCOPE 10 -- 3 METHODOLOGY 10 -- 3.1 STAKEHOLDER AND EXPERT INVOLVEMENT 10 -- 3.1.1 Stakeholders 10 -- 3.1.2 Experts 12 -- 3.2 CLINICAL QUESTIONS 12 -- 3.2.1 General questions 12 -- 3.2.2 Specific questions 12 -- 3.3 LITERATURE REVIEW 13 -- 3.3.1 Participants 13 -- 3.3.2 Intervention 13 -- 3.3.3 Comparator 13 -- 3.3.4 Outcome 13 -- 3.3.5 Study design 13 -- 3.3.6 Databases and date limits .14 -- 3.3.7 Search strategy .. 14 -- 3.3.8 Quality appraisal 17 -- 3.3.9 Data extraction 17 -- 3.4 ELABORATION OF RECOMMENDATION 19 -- 3.5 VALIDATION AND UPDATING THE GUIDELINE 20 -- 3.5.1 Validation process 20 -- 3.5.2 Updating of the guideline 20 -- 3.6 FUNDING AND DECLARATION OF INTEREST 20 -- 4 RESULTS FOR DIAGNOSIS 21 -- 4.1 HISTORY TAKING 21 -- 4.2 PHYSICAL EXAMINATION (OTTAWA ANKLE RULES EXCEPTED) 22 -- 4.2.1 Inspection and palpation 22 -- 4.2.2 Functional tests .. 22 -- 4.2.3 Timing of clinical examinations 23 -- 4.3 PHYSICAL EXAMINATION: OTTAWA ANKLE RULES (AND DERIVED) 24 -- 4.3.1 Description of the Ottawa ankle rules 24 -- 4.3.2 Validity of the Ottawa Ankle Rules 25 -- 4.3.3 Validity of other decision tools: tuning fork test, Bernese ankle rules, Leiden ankle rules and Utrecht ankle rules 27 -- 4.3.4 Implementation of the Ottawa ankle rules .. 29 -- 4.4 IMAGING 31 -- 4.4.1X-ray 31 -- 4.4.2 Ultrasonography 31 -- 4.4.3 Magnetic Resonance Imaging 32 -- 4.4.4 Computer assisted tomography .. 33 -- 4.5 DISCUSSION: DIAGNOSIS OF ANKLE SPRAIN 33 -- 4.6 RECOMMENDATIONS CONCERNING THE DIAGNOSIS OF ANKLE SPRAIN 35 -- 5 ALGORITHM FOR DIAGNOSIS 37 -- 6 RESULTS FOR THERAPY 38 -- 6.1 DRUG THERAPY 38 -- 6.1.1 Analgesic and anti-inflammatory oral medication 38 -- 6.1.2 Venotonic drugs 42 -- 6.1.3 Topical non-steroidal anti-inflammatory drugs (NSAIDs) 42 -- 6.1.4 Alternative topical therapies: Comfrey (Symphytum officinale) root extract ointment (“consoude”). 45 -- 6.2 REST, ICE, COMPRESSION AND ELEVATION 45 -- 6.2.1Rest versus mobilisation 46 -- 6.2.2 Ice versus no ice. 46 -- 6.2.3 Compression versus compression: intermittent pneumatic compression versus elastic bandage. 47 -- 6.2.4 Elevation versus no elevation 47 -- 6.2.5 RICE versus no RICE 47 -- 6.3 ELECTROPHYSICAL THERAPY 47 -- 6.3.1 Ultrasound 47 -- 6.3.2 Laser therapy 48 -- 6.4 ANKLE SUPPORT .. 49 -- 6.4.1 Immobilisation devices 49 -- 6.4.2 Support allowing partial mobilisation 50 -- 6.5 MANUAL THERAPY 51 -- 6.6 EXERCISE THERAPY 51 -- 6.7 OTHER CONSERVATIVE TREATMENTS 52 -- 6.7.1 Hyperbaric oxygen 52 -- 6.7.2 Proteolytic enzyme 52 -- 6.7.3 Hyaluronic acid intra-articular injections 53 -- 6.8 SURGICAL TREATMENT 53 -- 6.9 DISCUSSION: THERAPY FOR ACUTE LATERAL ANKLE SPRAIN 53 -- 6.10 RECOMMENDATIONS CONCERNING THE THERAPY OF ANKLE SPRAIN 55 -- 7 ALGORITHM FOR THERAPY 58 -- 8 IMPLEMENTATION OF THE GUIDELINE 59 -- 8.1 AT PRACTICE LEVEL: ADAPTATION TO INDIVIDUAL SITUATIONS. 59 -- 8.2 IMPLEMENTATION BY PROFESSIONAL SOCIETIES 59 -- 8.3 MONITORING THE GUIDELINE DISSEMINATION 59 -- 8.4 MONITORING THE GUIDELINE IMPLEMENTATION.59 -- REFERENCE LIST 60 -- APPENDICES 68 Link for e-copy: https://doi.org/10.57598/R197C Format of e-copy: PDF (1,6 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3164 Copies(0)
Status No copy Ankle sprains / Philip Roosen / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)
Ankle sprains : diagnosis and therapy - Synthesis [printed text] / Philip Roosen, Author ; Tine Willems, Author ; Roel De Ridder, Author ; Lorena San Miguel , Author ; Kirsten Holdt Henningsen, Author ; Dominique Paulus , Author ; An De Sutter, Author ; Pascale Jonckheer , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2013 . - 14 p. : Ill. ; A4. - (KCE Reports. Good Clinical Practice (GCP); 197CS) .
ISSN : D/2013/10.273/3 : € 0,00
Study n° : 2011-02
Languages : English (eng)
Descriptors: Indexation
2011-02 ; Ankle Injuries ; Diagnosis ; Practice Guideline [Publication type] ; R197 ; Therapeutics
Classification
WE 880 Ankle. FootLink for e-copy: https://doi.org/10.57598/R197CS Format of e-copy: PDF (460 kB) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3165 Copies(0)
Status No copy Annals of Physical and Rehabilitation Medicine / Dominic Perennou / Issy les Moulineaux [France] : Elsevier|Masson (2009)
[serial] See available issues Search in serial Annals of Physical and Rehabilitation Medicine = Ann Phys Rehabil Med [printed text] / Dominic Perennou, Editor . - Issy les Moulineaux [France] : Elsevier|Masson, 2009.
ISSN : 1877-0665
IF: http://www.journals.elsevier.com/annals-of-physical-and-rehabilitation-medicine
SJR: http://www.scimagojr.com/journalsearch.php?q=16500154708&tip=sid&clean=0
Indexed In:
ndex medicus: v52n1, Feb. 2009-
MEDLINE: v52n1, Feb. 2009-
PubMed: v52n1, Feb. 2009-
Languages : English (eng)
Descriptors: Classification
W 1 Serials. Periodicals
Indexation
Medicine ; Peer Review ; Periodicals ; RehabilitationAbstract: Une publication de la Société française de réadaptation et de médecine physique.
Neuf fois par an, la revue fait le point sur les travaux de recherche clinique, paraclinique ou fondamentale appliqués à la médecine de rééducation et de réadaptation dans les domaines de la neurologie, de appareil locomoteur, de la pathologie cardiovasculaire et respiratoire, et des fonctions sphinctériennes. Elle rend compte des travaux de spécialités complémentaires au travers de articles de synthèse, de articles originaux susceptibles de innover ou de développer des techniques ou des méthodes de réadaptation et de rééducation ainsi que sur les perspectives de aide aux personnes handicapées.Link for e-copy: http://www.sciencedirect.com/science/journal/18770657 Format of e-copy: PDF [Requires Subscription] Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3699 Annuaire des médecins spécialistes 2008-2009 / VBS-GBS / Bruxelles [Belgium] : Groupement des unions professionnelles de médecins spécialistes (GBS) - Verbond der Belgische Beroepsverenigingen van Geneesheren--Specialisten (VBS) (2008)
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