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Adult obesity and number of years lived with and without cardiovascular disease / M.C. Pardo Silva in Obesity, 14(2006)7 ([07/01/2006])  

[article] Adult obesity and number of years lived with and without cardiovascular disease [printed text] / M.C. Pardo Silva, Author ; Chris De Laet , Author ; W.J. Nusselder, Author ; A.A. Mamun, Author ; A. Peeters, Author . - 2006 . - 1264-73. Languages : English (eng) in Obesity > 14(2006)7 [07/01/2006] . - 1264-73 Descriptors: Classification W 1 Serials. Periodicals Indexation Aging ; Body Mass Index ; Cardiovascular diseases ; Cost of Illness ; Female ; Humans ; Journal Article ; Life Expectancy ; Male ; Middle Aged ; Myocardial infarction ; Obesity ; Overweight ; Peer Review ; Risk Assessment ; Risk Factors ; Stroke ; Time Factors ; United States Abstract: OBJECTIVE: To determine the differences in number of years lived free of cardiovascular disease (CVD) and number of years lived with CVD between men and women who were obese, pre-obese, or normal weight at 45 years of age. RESEARCH METHODS AND PROCEDURES: We constructed multistate life tables for CVD, myocardial infarction, and stroke, using data from 2551 enrollees (1130 men) in the Framingham Heart Study who were 45 years of age. RESULTS: Obesity and pre-obesity were associated with fewer number of years free of CVD, myocardial infarction, and stroke and an increase in the number of years lived with these diseases. Forty-five-year-old obese men with no CVD survived 6.0 years [95% confidence interval (CI), 4.1; 8.1] fewer than their normal weight counterparts, whereas, for women, the difference between obese and normal weight subjects was 8.4 years (95% CI: 6.2; 10.8). Obese men and women lived with CVD 2.7 (95% CI: 1.0; 4.4) and 1.4 years (95% CI: -0.3; 3.2) longer, respectively, than normal weight individuals. DISCUSSION: In addition to reducing life expectancy, obesity before middle age is associated with a reduction in the number of years lived free of CVD and an increase in the number of years lived with CVD. Such information is paramount for preventive and therapeutic decision-making by individuals and practitioners alike. Link for e-copy: http://www.nature.com/oby/journal/v14/n7/pdf/oby2006144a.pdf Format of e-copy: PDF [Open Access] (Embargo 2 years) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=2154 [article]

An economic evaluation of varicella vaccination in Italian adolescents / Nancy Thiry in Vaccine, 22(2004)27-28 ([09/09/2004])  

[article] An economic evaluation of varicella vaccination in Italian adolescents [printed text] / Nancy Thiry, Author ; Philippe Beutels, Author ; Francesco Tancredi, Author ; A. Zanetti, Author ; Paolo Bonanni, Author ; Giovanni Gabutti, Author ; Pierre Van Damme, Author . - 2004 . - 3546-3562. Languages : English (eng) in Vaccine > 22(2004)27-28 [09/09/2004] . - 3546-3562 Descriptors: Classification W 1 Serials. Periodicals Indexation Adolescent ; Adult ; Age Factors ; Aged ; Chickenpox Vaccine ; Child ; Child, Preschool ; Cost of Illness ; Cost-Benefit Analysis ; Economics ; Encephalitis, Varicella Zoster ; Epidemiology ; Female ; Hospitalization ; Humans ; Italy ; Journal Article ; Male ; Markov Chains ; Mass Immunization ; Middle Aged ; Netherlands ; Peer Review ; prevention and control ; statistics and numerical data [Subheading] Abstract: An economic evaluation was performed to assess five varicella vaccination scenarios targeted to 11-year-old Italian adolescents. The scenarios were: "compulsory vaccination" of all adolescents, recommended vaccination of susceptible adolescents on the basis of an "anamnestic screening", a "blood test" or a combination of both ("both tests") and vaccination of adolescents in the private sector, at the parents' charge ("private vaccination"). Probabilities and unit costs were taken from published sources and experts opinion. The accuracy of the anamnestic screening (81.6% sensitivity and 87.3% specificity) was derived from a separate descriptive study among 344 Italian adolescents. The costs and benefits of each scenario were simulated using a Markov model and cost-effectiveness, budget-impact and cost-benefit analyses were conducted. Of all considered scenarios, "both tests" and "anamnestic screening" were the most appealing options with an estimated net direct cost of 5058 and 8929 per life-year gained (compared to no vaccination) versus 14,693-42,842 for the other scenarios. These two scenarios further resulted in substantial net savings for society (over 600,000 per cohort, BCR: 2.17). The need for a serological confirmation was highly dependent on the sensitivity of the anamnestic screening, which is believed to increase once such a program is launched. For practical considerations, "anamnestic screening" seems to be the most convenient option. Link for e-copy: http://tiny.cc/xktyn Format of e-copy: VDIC IP recognition Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=1773 [article]

Dollars, DALYs and Decisions / D. Chilsholm / Geneva [Switzerland] : World Health Organisation (WHO) (2006)  

Dollars, DALYs and Decisions : Economic Aspects of the Mental Health System [printed text] / D. Chilsholm, Author ; S. Saxena, Author ; M. van Ommeren . - Geneva [Switzerland] : World Health Organisation (WHO), 2006 . - 56 p. : ill. ; 30 cm. ISBN : 978-92-4-156333-8 : € 0,00 Languages : English (eng) Descriptors: Classification WA 305 Mental health of special population groups Indexation Cost of Illness ; Cost-Benefit Analysis ; Electronic books ; Health Planning ; Mental Health Services Abstract: The widening recognition of mental health as a significant international public health issue has led to an increasing need to demonstrate that investment of resources into service development is both required and also worthwhile. In particular, there is a need to generate evidence on mental health care strategies that are not only effective and appropriate but are also cost-effective and sustainable. Aimed at health policy-makers and service researchers with an interest in strengthening mental health systems, this publication sets out to highlight the need for and relevance of an economic dimension to decision-making and to summarize results from existing mental health economic analyses Contents note: Executive Summary -- 1. Introduction 11 1.1 Rationale for an economic perspective in mental health policy and practice 11 -- 1.2 Economics for mental health planning and evaluation: a systems approach 14 -- 2. Measuring the burden of mental disorders: from DALYs to dollars 19 -- 2.1 Epidemiological burden: disability-adjusted life years (DALYs) 19 -- 2.2 Economic burden: cost-of-illness studies 21 -- 3. Reducing the burden of mental disorders: from global to national evaluation 23 -- 3.1 WHO framework for cost-effectiveness analysis 23 -- 3.2 Global evaluation of the cost-effectiveness of interventions 25 -- 3.3 National evaluation of the cost-effectiveness of interventions 30 -- 4. Priority-setting and resource allocation for mental health system development 37 -- 4.1 Decision-making criteria for resource planning and allocation in health 37 -- 4.2 Development of a priority-setting framework for mental health policy 39 -- 4.3 Scaling up priority interventions: financial planning and budgetary allocation 43 -- 5. Conclusion 47 -- References 49 Appendices 53 Link for e-copy: http://www.who.int/mental_health/evidence/dollars_dalys_and_decisions.pdf Format of e-copy: PDF [Open Access] (1,52 MB) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=754

Medical devices / World Health Organization / Geneva [Switzerland] : World Health Organisation (WHO) (2010)

Medical devices : managing the mismatch : an outcome of the priority medical devices project [printed text] / World Health Organization, Author . - Geneva [Switzerland] : World Health Organisation (WHO), 2010 . - 129 p. : ill. ; A4. ISBN : 978-92-4-156404-5 : $ 50,00 Languages : English (eng) Descriptors: Indexation Biomedical Engineering ; Cost of Illness ; Equipment and Supplies ; Public Health ; Research Classification WX 147 Equipment and supplies Abstract: Choosing a medical device is complex and requires a transparent process based on reason, evidence and assessment of prioritized public health needs. Poor choices lead to inappropriate use or non-use of medical devices and a waste of resources. This report suggests how an agenda to improve access to appropriate medical devices could be devised from applying the crucial 4 components - Availability, Accessibility, Appropriateness, and Affordability, to the 15 global high-burden diseases and some cross-cutting issues. The results of this exercise suggest several areas of research necessary to help make medical devices more available, accessible, appropriate, and affordable. Examples include: development of a kit containing simple and affordable technologies for measuring blood pressure, blood glucose and cholesterol levels, which could assess cardiovascular risk; developing portable, affordable spirometry equipment for accurate diagnosis and prognosis of chronic obstructive pulmonary disease (COPD) or asthma in low-resource settings; and the development of more appropriate hearing aids which could potentially help people with hearing impairments whatever their age or setting. An example of a key cross-cutting issue is the need to develop simple, affordable, and reliable sensitivity tests for bacterial and viral antigens. Such tests could replace culture systems to detect the presence of pathogens and effectively and efficiently help to diagnose many high-burden infections and neglected tropical diseases. The Priority Medical Devices (PMD) project applied the "4 A" questions to some examples of identified key medical devices to further explore the downstream issues associated with poor access to appropriate medical devices. The PMD project hopes all players in the medical device arena can collectively use the findings of this report to help make public health a central focus of their activities, along with the work on policies, tools and innovations of the WHO Global Initiative for Health Technologies. Contents note: Overview -- 1. Introduction -- 2. Medical devices -- 3. Public health needs -- 4. Priority Medical Devices project: methods used -- 5. Medical devices: problems and possible solutions -- 6. Towards appropriate medical devices: options for future research -- References -- Glossary -- Annexes Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=2230

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More is not better in the early care of acute myocardial infarction / Hans Van Brabandt in European Heart Journal, 27(2006)22 ([10/20/2006])  

[article] More is not better in the early care of acute myocardial infarction : a prospective cohort analysis on administrative databases [printed text] / Hans Van Brabandt , Author ; Dirk Ramaekers ; Luc Bonneux ; Cécile Camberlin , Author ; France Vrijens ; Yves Parmentier . - 2006 . - 2649-2654. Languages : English (eng) in European Heart Journal > 27(2006)22 [10/20/2006] . - 2649-2654 Descriptors: Classification WG 300 Coronary vessels. Coronary disease Indexation Administrative databases ; Cost of Illness ; England ; Journal Article ; Myocardial infarction ; Peer Review ; Physician's Practice Patterns ; Reperfusion Keywords: Clinical practice variation Abstract: Aims To assess the outcome and costs of patients with acute myocardial infarction (AMI) after initial admission to hospitals with or without catheterization facilities in Belgium. Methods and results From a nationwide hospital register, we retrieved the data of 34 961 patients discharged during 1999-2001 with a principal diagnosis of AMI. They were initially admitted to hospitals without catheterization facilities (A), with diagnostic (B1) or interventional catheterization facilities (B2). Mortality has been recorded till the end of 2003 and re-admissions till the end of 2001. The mortality hazard ratio and 95% CI of 5 years mortality of A vs. B2 was 1.01 (0.97, 1.06) and of B1 vs. B2 was 1.03 (0.98, 1.09). Re-admission rates and 95% CI for cardiovascular reason per 100 patient-years were 23.5 (22.7, 24.3) for A, 23.8 (22.5, 25.1) for B1, and 22.0 (21.2, 22.9) for B2. The mean cost in hospital of a patient at low risk with a single stay was in A {euro}4072 (median: 3,861; IQR: 4467-3476), in B1 {euro}5083 (median: 5153; IQR: 5769-4340), and in B2 {euro}7741 (median: 7553; IQR: 8211-7298). Conclusion Services with catheterization facilities compared with services without them showed no better health outcomes, but delivered more expensive care. Link for e-copy: http://eurheartj.oxfordjournals.org/cgi/content/full/27/22/2649 Format of e-copy: HTML Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=514 [article]

Part 1. The socio-economic burden of hospital acquired infection / Rosalind Plowman / London : Public Health Laboratory Service (1999)

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Pitfalls in economic analysis / Hans Van Brabandt in European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 12(2010)05 ([05/17/2010])  

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Pitfalls in health-economic evaluations / Hans Van Brabandt in European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 11(2009)12 ([12/01/2009])  

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Prevalence, burden, and control of syphilis in Haiti's rural Artibonite region / D.W. Fitzgerald in International journal of infectious diseases, 2(1998)4 ([01/01/1998])  

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A review of the literature on the economics of noncompliance / Irina Cleemput in Health Policy, 59(2002)1 ([01/01/2002])  

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The contribution of health to the economy in the European Union / Marc Suhrcke / Brussels [Belgium] : European Communities (2005)  

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The health and economic burden of rotavirus disease in Belgium / J Bilcke in European journal of pediatrics, 167(2008)12 ([12/01/2008])  

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The mental health context / Michelle Funk ; Benedetto Saraceno ; Soumitra Pathare ; Alan J. Flisher ; World Health Organization / Geneva [Switzerland] : World Health Organisation (WHO) (2003)

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