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Author Ronald P. Zweemer |
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Cancer de l’ovaire / Ignace Vergote / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2016)
Cancer de l’ovaire : Diagnostic, traitement et suivi – Résumé [printed text] / Ignace Vergote, Author ; Joan Vlayen , Author ; Pauline Heus, Author ; Jacob P. Hoogedam, Author ; Johanna A.A.G. Damen, Author ; Fleur van de Wetering, Author ; Frederieke Van der Baan, Author ; Claire Bourgain, Author ; Jacques De Greve, Author ; David Debruyne, Author ; Maxime Fastrez, Author ; Manon Huizing, Author ; Joseph Kerger, Author ; Frédéric Kridelka, Author ; Sigrid Stroobandts, Author ; Wiebren T. Jalma, Author ; Peter Van Dam, Author ; Vincent Van de Caveye, Author ; Geert Villeirs, Author ; Peter Vuylsteke, Author ; Nicolas Fairon , Author ; Ronald P. Zweemer, Author ; Lotty Hooft, Author ; Rob Scholten, Author ; Leen Verleye, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2016 . - 11 p. : ill., ; A4. - (KCE Reports B. Good Clinical Practice (GCP); 268Bs) .
ISSN : D/2016/10.273/47 : € 0,00
Etude 2014-05-01
Languages : French (fre)
Descriptors: Indexation
2014-05-01 ; CA-125 Antigen ; Frozen Sections ; Laparoscopy ; Lymph Node Excision ; Ovarian Neoplasms ; Practice Guideline [Publication type] ; R268
Classification
WP 322 NeoplasmsAbstract: Le cancer de l’ovaire touche chaque année environ 900 femmes en Belgique. Le Centre Fédéral d’Expertise des Soins de Santé (KCE) a élaboré, en collaboration avec des cliniciens et le Collège d’Oncologie, des recommandations cliniques pour le diagnostic, le traitement et le suivi du cancer de l’ovaire, sur base des études scientifiques les plus récentes. Les étapes suivantes consisteront à développer des indicateurs de qualité pour l’ensemble de la prise en charge de ce cancer, puis à envoyer aux prestataires de soins un feedback sur leurs résultats afin de les inciter à prendre les mesures spécifiques nécessaires en vue d’améliorer la qualité des soins Link for e-copy: https://doi.org/10.57598/R268BS Format of e-copy: PDF (944 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3857 Eierstokkanker / Ignace Vergote / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2016)
Eierstokkanker : diagnose, behandeling en follow-up – Samenvatting [printed text] / Ignace Vergote, Author ; Joan Vlayen , Author ; Pauline Heus, Author ; Jacob P. Hoogedam, Author ; Johanna A.A.G. Damen, Author ; Fleur van de Wetering, Author ; Frederieke Van der Baan, Author ; Claire Bourgain, Author ; Jacques De Greve, Author ; David Debruyne, Author ; Maxime Fastrez, Author ; Manon Huizing, Author ; Joseph Kerger, Author ; Frédéric Kridelka, Author ; Sigrid Stroobandts, Author ; Wiebren T. Jalma, Author ; Peter Van Dam, Author ; Vincent Van de Caveye, Author ; Geert Villeirs, Author ; Peter Vuylsteke, Author ; Nicolas Fairon , Author ; Ronald P. Zweemer, Author ; Lotty Hooft, Author ; Rob Scholten, Author ; Leen Verleye, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2016 . - 13 p. : ill., ; A4. - (KCE Reports A. Good Clinical Practice (GCP); 268AS) .
ISSN : D/2016/10.273/46 : € 0,00
Studie 2014-05-01
Languages : Dutch (nla)
Descriptors: Indexation
2014-05-01 ; CA-125 Antigen ; Frozen Sections ; Laparoscopy ; Lymph Node Excision ; Ovarian Neoplasms ; Practice Guideline [Publication type] ; R268
Classification
WP 322 NeoplasmsAbstract: Eierstokkanker wordt jaarlijks bij bijna 900 vrouwen in België vastgesteld. Het Federaal Kenniscentrum voor de Gezondheidszorg (KCE) ontwikkelde samen met een groep van clinici en het College voor Oncologie een klinische richtlijn voor de diagnose, behandeling en follow-up van eierstokkanker op basis van de meest recente wetenschappelijke bevindingen. In een volgende fase zullen kwaliteitsindicatoren voor alle aspecten van de behandeling worden ontwikkeld, en zullen de zorgverleners feedback ontvangen over hun resultaten. De uiteindelijke bedoeling is om gerichte acties te ondernemen om de kwaliteit, waar nodig, te verbeteren. Link for e-copy: https://doi.org/10.57598/R268AS Format of e-copy: PDF (944 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3858 Ovarian cancer / Ignace Vergote / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2016)
Ovarian cancer : diagnosis, treatment and follow-up [printed text] / Ignace Vergote, Author ; Joan Vlayen , Author ; Pauline Heus, Author ; Jacob P. Hoogedam, Author ; Johanna A.A.G. Damen, Author ; Fleur van de Wetering, Author ; Frederieke Van der Baan, Author ; Claire Bourgain, Author ; Jacques De Greve, Author ; David Debruyne, Author ; Maxime Fastrez, Author ; Manon Huizing, Author ; Joseph Kerger, Author ; Frédéric Kridelka, Author ; Sigrid Stroobandts, Author ; Wiebren T. Jalma, Author ; Peter Van Dam, Author ; Vincent Van de Caveye, Author ; Geert Villeirs, Author ; Peter Vuylsteke, Author ; Nicolas Fairon , Author ; Ronald P. Zweemer, Author ; Lotty Hooft, Author ; Rob Scholten, Author ; Leen Verleye, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2016 . - 72 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 268C) .
ISSN : D/2016/10.273/49 : € 0,00
Study 2014-05-01
Languages : English (eng)
Descriptors: Indexation
2014-05-01 ; CA-125 Antigen ; Frozen Sections ; Laparoscopy ; Lymph Node Excision ; Ovarian Neoplasms ; Practice Guideline [Publication type] ; R268
Classification
WP 322 NeoplasmsContents note: TABLE OF CONTENTS 1 -- SCIENTIFIC REPORT 7 -- 1 INTRODUCTION 7 -- 1.1 BACKGROUND 7 -- 1.2 THE NEED FOR A GUIDELINE 10 -- 1.3 SCOPE 10 -- 1.4 REMIT OF THE GUIDELINE 10 -- 1.4.1 Overall objectives 10 -- 1.4.2 Multidisciplinary approach 10 -- 1.4.3 Patient-centred care 10 -- 1.4.4 Target users of the guideline 11 -- 1.5 STATEMENT OF INTENT 11 -- 1.6 FUNDING AND DECLARATION OF INTEREST 11 -- 2 METHODOLOGY 12 -- 2.1 INTRODUCTION 12 -- 2.2 THE GUIDELINE DEVELOPMENT GROUP (GDG) 12 -- 2.3 GENERAL APPROACH 12 -- 2.4 CLINICAL RESEARCH QUESTIONS 12 -- 2.5 LITERATURE SEARCH AND STUDY SELECTION 13 -- 2.5.1 Study design 13 -- 2.5.2 Databases and date limits 13 -- 2.5.3 Study selection 14 -- 2.6 QUALITY APPRAISAL 14 -- 2.7 DATA EXTRACTION 15 -- 2.8 STATISTICAL ANALYSIS 15 -- 2.9 GRADING EVIDENCE 16 -- 2.9.1 Therapeutic interventions 16 -- 2.9.2 Diagnostic test accuracy 18 -- 2.9.3 Prognostic studies 19 -- 2.10 FORMULATION OF RECOMMENDATIONS 19 -- 2.11 EXTERNAL REVIEW 21 -- 2.11.1 Healthcare professionals 21 -- 2.11.2 Patient representatives 22 -- 2.12 FINAL VALIDATION 22 -- 3 CLINICAL RECOMMENDATIONS: EARLY STAGE DISEASE 22 -- 3.1 INTRODUCTION 22 -- 3.2 PRE-OPERATIVE ASSESSMENT PELVIC MASS 22 -- 3.2.1 Background 22 -- 3.2.2 Results 23 -- 3.3 INTRA-OPERATIVE FROZEN SECTION 27 -- 3.3.1 Background 27 -- 3.3.2 Results 27 -- 3.4 LYMPHADENECTOMY 29 -- 3.4.1 Background 29 -- 3.4.2 Results 29 -- 3.5 ADJUVANT CHEMOTHERAPY 37 -- 3.5.1 Background 37 -- 3.5.2 Results 37 -- 3.6 LAPAROSCOPIC SURGERY 43 -- 3.6.1 Background 43 -- 3.6.2 Results 43 -- 4 CLINICAL RECOMMENDATIONS: ADVANCED STAGE DISEASE 45 -- 4.1 INTRODUCTION 45 -- 4.2 LAPAROSCOPY, PET-CT AND MRI TO PREDICT END RESULT OF CYTOREDUCTIVE SURGERY 45 -- 4.2.1 Laparoscopy 46 -- 4.2.2 MRI or CT 46 -- 4.2.3 Diffusion-weighted MRI (DW-MRI) 47 -- 4.2.4 18F-FDG PET-CT 47 -- 4.3 AIM OF CYTOREDUCTIVE SURGERY: NO MACROSCOPIC DISEASE 49 -- 4.3.1 Background 49 -- 4.3.2 Prognostic value of the maximal diameter of residual disease at the end of surgery 49 -- 4.3.3 Effect of (ultra)radical surgery 50 -- 4.4 NEOADJUVANT CHEMOTHERAPY AND INTERVAL DEBULKING VERSUS UPFRONT SURGERY 53 -- 4.5 INTRA-PERITONEAL CHEMOTHERAPY 55 -- 4.6 FIRST-LINE WEEKLY (DOSE-DENSE) CHEMOTHERAPY 58 -- 5 CLINICAL RECOMMENDATIONS: FOLLOW-UP 60 -- 5.1 BACKGROUND 60 -- 5.2 ROUTINE CA125 MEASUREMENTS DURING FOLLOW-UP 60 -- 6 IMPLEMENTATION AND UPDATING OF THE GUIDELINE 62 -- 6.1 IMPLEMENTATION 62 -- 6.1.1 Actors of the implementation of this guideline 62 -- 6.1.2 Barriers and facilitators for implementation of this guideline 63 -- 6.2 MONITORING THE QUALITY OF CARE 63 -- 6.3 GUIDELINE UPDATE 64 -- REFERENCES 65 Link for e-copy: https://doi.org/10.57598/R268C Format of e-copy: PDF (1,4 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3853 Ovarian cancer / Ignace Vergote / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2016)
Ovarian cancer : diagnosis, treatment and follow-up - Appendix [printed text] / Ignace Vergote, Author ; Joan Vlayen , Author ; Pauline Heus, Author ; Jacob P. Hoogedam, Author ; Johanna A.A.G. Damen, Author ; Fleur van de Wetering, Author ; Frederieke Van der Baan, Author ; Claire Bourgain, Author ; Jacques De Greve, Author ; David Debruyne, Author ; Maxime Fastrez, Author ; Manon Huizing, Author ; Joseph Kerger, Author ; Frédéric Kridelka, Author ; Sigrid Stroobandts, Author ; Wiebren T. Jalma, Author ; Peter Van Dam, Author ; Vincent Van de Caveye, Author ; Geert Villeirs, Author ; Peter Vuylsteke, Author ; Nicolas Fairon , Author ; Ronald P. Zweemer, Author ; Lotty Hooft, Author ; Rob Scholten, Author ; Leen Verleye, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2016 . - 359 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 268S) .
ISSN : D/2016/10.273/50 : € 0,00
Study 2014-05-01
Languages : English (eng)
Descriptors: Indexation
2014-05-01 ; CA-125 Antigen ; Frozen Sections ; Laparoscopy ; Lymph Node Excision ; Ovarian Neoplasms ; Practice Guideline [Publication type] ; R268
Classification
WP 322 NeoplasmsContents note: APPENDIX REPORT 1 -- 1. COMPOSITION OF THE GUIDELINE DEVELOPMENT GROUP 12 -- 1.1. COMPOSITION OF THE GUIDELINE DEVELOPMENT GROUP 12 -- 1.2. COMPOSITION OF THE KCE EXPERT TEAM 13 -- 1.3. EXTERNAL RESEARCHERS INVOLVED IN THE GUIDELINE DEVELOPMENT 13 -- 2. PICO RESEARCH QUESTIONS 14 -- 2.1. PRE-OPERATIVE ASSESSMENT PELVIC MASS 14 -- 2.2. INTRA-OPERATIVE FROZEN SECTION 15 -- 2.3. LYMPHADENECTOMY 16 -- 2.4. ADJUVANT CHEMOTHERAPY 16 -- 2.5. LAPAROSCOPIC SURGERY 17 -- 2.6. LAPAROSCOPY, PET-CT AND MRI TO PREDICT END RESULT OF CYTOREDUCTIVE SURGERY 17 -- 2.7. AIM OF CYTOREDUCTIVE SURGERY: NO MACROSCOPIC DISEASE? 18 -- 2.8. NEOADJUVANT CHEMOTHERAPY 19 -- 2.9. INTRA-PERITONEAL CHEMOTHERAPY 19 -- 2.10. FIRST-LINE WEEKLY (DOSE DENSE) CHEMOTHERAPY 19 -- 2.11. ROUTINE CA 125 MEASUREMENT DURING FOLLOW-UP 20 -- 3. SEARCH STRATEGIES 21 -- 3.1. PRE-OPERATIVE ASSESSMENT PELVIC MASS 21 -- 3.2. INTRA-OPERATIVE FROZEN SECTION 24 -- 3.2.1. Systematic reviews 24 -- 3.2.2. Randomized controlled trials 26 -- 3.2.3. Diagnostic test accuracy studies 28 -- 3.3. LYMPHADENECTOMY 30 -- 3.3.1. Systematic reviews 30 -- 3.3.2. Primary studies 31 -- 3.4. ADJUVANT CHEMOTHERAPY 33 -- 3.4.1. RCTs and non-randomized studies 33 -- 3.5. LAPAROSCOPIC SURGERY 41 -- 3.5.1. Systematic reviews 41 -- 3.5.2. Primary studies 44 -- 3.6. LAPAROSCOPY, PET-CT AND MRI TO PREDICT END RESULT OF CYTOREDUCTIVE SURGERY 47 -- 3.6.1. Systematic reviews 47 -- 3.6.2. RCTs 49 -- 3.6.3. Diagnostic accuracy studies 51 -- 3.7. AIM OF CYTOREDUCTIVE SURGERY: NO MACROSCOPIC DISEASE? 53 -- 3.7.1. RCTs and comparative observational studies – update Elattar 2011 53 -- 3.7.2. RCTs and comparative observational studies – Update Ang et al. 56 -- 3.8. NEO-ADJUVANT CHEMOTHERAPY AND INTERVAL DEBULKING VERSUS UPFRONT SURGERY 62 -- 3.8.1. Systematic reviews 62 -- 3.8.2. RCTs 65 -- 3.9. INTRA-PERITONEAL CHEMOTHERAPY 69 -- 3.10. FIRST-LINE WEEKLY (DOSE DENSE) CHEMOTHERAPY 75 -- 3.11. ROUTINE CA 125 MEASUREMENT DURING FOLLOW-UP 80 -- 3.11.1. Systematic reviews 80 -- 3.11.2. Randomized controlled trials 82 -- 3.12. PATIENT PREFERENCES 86 -- 4. STUDY SELECTION AND QUALITY APPRAISAL 95 -- 4.1. QUALITY APPRAISAL TOOLS 95 -- 4.1.1. Guidelines 95 -- 4.1.2. Systematic reviews 96 -- 4.1.3. Diagnostic accuracy studies 98 -- 4.1.4. Primary studies for therapeutic interventions 99 -- 4.2. STUDY SELECTION AND QUALITY APPRAISAL 101 -- 4.2.1. Pre-operative assessment pelvic mass 101 -- 4.2.2. Intra-operative frozen section 103 -- 4.2.3. Lymphadenectomy 110 -- 4.2.4. Adjuvant chemotherapy 118 -- 4.2.5. Laparoscopic surgery 126 -- 4.2.6. Laparoscopy, PET-CT and MRI to predict end result of cytoreductive surgery 131 -- 4.2.7. Aim of cytoreductive surgery: no macroscopic disease? 139 -- 4.2.8. Neo-adjuvant chemotherapy and interval debulking versus upfront surgery 150 -- 4.2.9. Intra-peritoneal chemotherapy 154 -- 4.2.10. First-line weekly (dose dense) chemotherapy 159 -- 4.2.11. Routine CA125 measurement during follow-up 164 -- 5. EVIDENCE TABLES BY CLINICAL QUESTION 169 -- 5.1. PRE-OPERATIVE ASSESSMENT PELVIC MASS 169 -- 5.2. INTRA-OPERATIVE FROZEN SECTION 171 -- 5.3. LYMPHADENECTOMY 189 -- 5.4. ADJUVANT CHEMOTHERAPY 215 -- 5.5. LAPAROSCOPIC SURGERY IN EARLY STAGE OVARIAN CANCER 219 -- 5.5.1. Systematic reviews 219 -- 5.5.2. Primary studies 222 -- 5.6. LAPAROSCOPY, PET-CT AND MRI TO PREDICT END RESULT OF CYTOREDUCTIVE SURGERY 232 -- 5.7. AIM OF CYTOREDUCTIVE SURGERY: NO MACROSCOPIC DISEASE? 246 -- 5.7.1. Prognostic value end result of surgery 246 -- 5.7.2. Effect of (ultra)radical surgery 266 -- 5.8. NEO-ADJUVANT CHEMOTHERAPY AND INTERVAL DEBULKING VERSUS UPFRONT SURGERY 271 -- 5.8.1. Systematic reviews 271 -- 5.8.2. RCTs 272 -- 5.9. INTRAPERITONEAL CHEMOTHERAPY 277 -- 5.10. FIRST-LINE WEEKLY (DOSE DENSE) CHEMOTHERAPY 280 -- 5.11. ROUTINE CA125 MEASUREMENT DURING FOLLOW-UP 283 -- 6. SUMMARY OF FINDINGS TABLES AND GRADE PROFILES 286 -- 6.1. PRE-OPERATIVE ASSESSMENT PELVIC MASS 286 -- 6.2. INTRA-OPERATIVE FROZEN SECTION 289 -- 6.3. ADJUVANT CHEMOTHERAPY 291 -- 6.4. LAPAROSCOPIC SURGERY IN EARLY STAGE OVARIAN CANCER 294 -- 6.5. LAPAROSCOPY, PET-CT AND MRI TO PREDICT END RESULT OF CYTOREDUCTIVE SURGERY 294 -- 6.5.1. Laparoscopy 294 -- 6.5.2. MRI or CT 296 -- 6.5.3. DW-MRI 298 -- 6.5.4. PET-CT 299 -- 6.6. AIM OF CYTOREDUCTIVE SURGERY: NO MACROSCOPIC DISEASE? 301 -- 6.6.1. Prognostic value end result of surgery 301 -- 6.6.2. Effect of (ultra)radical surgery 304 -- 6.7. NEO-ADJUVANT CHEMOTHERAPY AND INTERVAL DEBULKING VERSUS UPFRONT SURGERY 307 -- 6.8. INTRAPERITONEAL CHEMOTHERAPY 314 -- 6.9. FIRST-LINE WEEKLY (DOSE DENSE) CHEMOTHERAPY 316 -- 6.10. ROUTINE CA125 MEASUREMENT DURING FOLLOW-UP 317 -- 7. FOREST PLOTS 318 -- 7.1. INTRA-OPERATIVE FROZEN SECTION 318 -- 7.2. AIM OF CYTOREDUCTIVE SURGERY: NO MACROSCOPIC DISEASE? 322 -- 7.3. NEOADJUVANT CHEMOTHERAPY AND INTERVAL DEBULKING VERSUS UPFRONT SURGERY 327 -- 7.4. FIRST-LINE WEEKLY (DOSE DENSE) CHEMOTHERAPY 330 -- 8. EXTERNAL REVIEW 331 -- 8.1. STAKEHOLDER REVIEW 331 -- REFERENCES 333 Link for e-copy: https://doi.org/10.57598/R268S Format of e-copy: PDF (4,2 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3855 Ovarian cancer / Ignace Vergote / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2016)