Author details
Author Tom De Keyser |
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Dépression majeure (de l’adulte) / Eirini Karyotaki / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2014)
Dépression majeure (de l’adulte) : efficacité à long terme de la psychothérapie, seule ou en combinaison avec des antidépresseurs - Résumé [printed text] / Eirini Karyotaki, Author ; Yolba Smit, Author ; Pim Cuijpers, Author ; Monique Debauche, Author ; Tom De Keyser, Author ; Hilde Habraken, Author ; William Pitchot, Author ; Filip Reas, Author ; Dominique Salomez, Author ; Benoit Gillain, Author ; Nicolas Fairon , Author ; Dominique Paulus , Author ; Jo Robays, Author ; Kirsten Holdt Henningsen, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2014 . - 7 p. : ill., ; A4. - (KCE Reports B. Good Clinical Practice (GCP); 230BS) .
ISSN : D/2014/10.273/70 : € 0,00
Etude 2013-20
Languages : French (fre)
Descriptors: Indexation
2013-20 ; Antidepressive Agents ; Depression ; Guideline [Publication Type] ; Psychotherapy ; R230
Classification
WM 171.5 Depression. Depressive disorderAbstract: Le Centre Fédéral d’Expertise des Soins de Santé (KCE) a mené une étude sur l’efficacité de la psychothérapie, seule ou en combinaison avec les antidépresseurs. La meilleure option est la psychothérapie combinée aux médicaments antidépresseurs, mais si la personne ne souhaite pas cette approche, c’est la psychothérapie qui doit être proposée en premier choix. Elle est aussi efficace que les médicaments à court terme, et même plus efficace à long terme. Les médicaments antidépresseurs ne devraient de préférence pas être prescrits seuls étant donné qu’ils sont moins efficaces à long terme que leur combinaison avec une psychothérapie. Link for e-copy: https://doi.org/10.57598/R230BS Format of e-copy: PDF (296 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3445 Copies(0)
Status No copy Majeure Depressie (bij volwassenen) / Eirini Karyotaki / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2014)
Majeure Depressie (bij volwassenen) : doeltreffendheid op de lange termijn van psychotherapie, op zichzelf of in combinatie met antidepressiva - Samenvatting [printed text] / Eirini Karyotaki, Author ; Yolba Smit, Author ; Pim Cuijpers, Author ; Monique Debauche, Author ; Tom De Keyser, Author ; Hilde Habraken, Author ; William Pitchot, Author ; Filip Reas, Author ; Dominique Salomez, Author ; Benoit Gillain, Author ; Nicolas Fairon , Author ; Dominique Paulus , Author ; Jo Robays, Author ; Kirsten Holdt Henningsen, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2014 . - 7 p. : ill., ; A4. - (KCE Reports A. Good Clinical Practice (GCP); 230AS) .
ISSN : D/2014/10.273/69 : € 0,00
Studie 2013-20
Languages : Dutch (nla)
Descriptors: Indexation
2013-20 ; Antidepressive Agents ; Depression ; Guideline [Publication Type] ; Psychotherapy ; R230
Classification
WM 171.5 Depression. Depressive disorderAbstract: Het Federaal Kenniscentrum voor de Gezondheidszorg (KCE) onderzocht de doeltreffendheid van psychotherapie, alleen of in combinatie met antidepressiva. Het beste worden psychotherapie en antidepressiva gecombineerd, maar als de patiënt deze aanpak niet ziet zitten moet psychotherapie de voorkeur krijgen. Psychotherapie is namelijk even doeltreffend als antidepressiva op korte termijn en zelfs doeltreffender op lange termijn. Antidepressiva worden beter niet alleen voorgeschreven, want ze zijn op lange termijn minder doeltreffend dan wanneer ze worden gecombineerd met psychotherapie. Link for e-copy: https://doi.org/10.57598/R230AS Format of e-copy: PDF (299 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3446 Copies(0)
Status No copy The long-term efficacy of psychotherapy, alone or in combination with antidepressants, in the treatment of adult major depression / Eirini Karyotaki / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2014)
The long-term efficacy of psychotherapy, alone or in combination with antidepressants, in the treatment of adult major depression [printed text] / Eirini Karyotaki, Author ; Yolba Smit, Author ; Pim Cuijpers, Author ; Monique Debauche, Author ; Tom De Keyser, Author ; Hilde Habraken, Author ; William Pitchot, Author ; Filip Reas, Author ; Dominique Salomez, Author ; Benoit Gillain, Author ; Nicolas Fairon , Author ; Dominique Paulus , Author ; Jo Robays, Author ; Kirsten Holdt Henningsen, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2014 . - 70 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 230C) .
ISSN : D/2014/10.273/72 : € 0,00
Study 2013-20
Languages : English (eng)
Descriptors: Indexation
2013-20 ; Antidepressive Agents ; Depression ; Guideline [Publication Type] ; Psychotherapy ; R230
Classification
WM 171.5 Depression. Depressive disorderContents note: SCIENTIFIC REPORT 8 -- 1 INTRODUCTION 8 -- 1.1 INCIDENCE AND PREVALENCE 8 -- 1.2 DIAGNOSIS AND CLASSIFICATION OF MAJOR DEPRESSION. 9 -- 1.3 COURSE OF THE DISEASE 9 -- 2 OBJECTIVES AND SCOPE OF THIS GUIDELINE 10 -- 2.1 BACKGROUND 10 -- 2.2 THE NEED FOR A GUIDELINE 10 -- 2.3 SCOPE 10 -- 2.4 REMIT OF THE GUIDELINE 10 -- 2.4.1 Overall objectives 10 -- 2.4.2 Target users of the guideline 11 -- 2.5 STATEMENT OF INTENT 11 -- 2.6 FUNDING AND DECLARATION OF INTEREST 11 -- 3 METHODOLOGY 12 -- 3.1 INTRODUCTION 12 -- 3.2 THE GUIDELINE DEVELOPMENT GROUP 12 -- 3.3 CLINICAL RESEARCH QUESTIONS 12 -- 3.4 SELECTION CRITERIA 12 -- 3.4.1 Type of studies 12 -- 3.4.2 Definitions 12 -- 3.4.3 Type of patients 13 -- 3.4.4 Types of interventions 13 -- 3.4.5 Types of comparators 14 -- 3.4.6 Outcomes 14 -- 3.4.7 Power calculations 14 -- 3.5 SEARCH STRATEGY AND STUDY SELECTION 14 -- 3.6 QUALITY APPRAISAL 15 -- 3.7 DATA EXTRACTION, DESCRIPTION AND ANALYSIS 15 -- 3.7.1 Calculation of effect sizes 16 -- 3.7.2 Meta-analysis 16 -- 3.8 GRADING EVIDENCE 16 -- 3.9 FORMULATION OF RECOMMENDATIONS 19 -- 4 RESULTS RESEARCH QUESTION ONE 20 -- 4.1 SYSTEMATIC REVIEW 20 -- 4.1.1 Characteristics of included SR: MBCT vs. control groups 20 -- 4.1.2 Results of included SR: maintenance MBCT vs. control groups 20 -- 4.2 RCT 21 -- 4.2.1 Characteristics of included RCTs: psychotherapy (acute phase) vs. control groups 21 -- 4.2.2 Characteristics of included RCTs: maintenance psychotherapy vs. control groups 25 -- 4.2.3 Results of included RCTs: psychotherapy vs. control groups in adults with MDD, acute phase treatment 28 -- 4.2.4 Results of included RCTs: psychotherapy vs. control groups in adults who had had MDD, maintenance treatment 30 -- 4.3 CONCLUSIONS: MAIN PSYCHOTHERAPY INTERVENTIONS ONLY VS. NO TREATMENT 31 -- 5 RESULTS RESEARCH QUESTION TWO 31 -- 5.1 SYSTEMATIC REVIEWS 31 -- 5.1.1 Characteristics of included SRs: psychotherapy vs. ADM 31 -- 5.1.2 Results of included SRs: psychotherapy vs. ADM 32 -- 5.2 RCTS 33 -- 5.2.1 Characteristics of included RCTs: psychotherapy (acute phase) vs. ADM 33 -- 5.2.2 Characteristics of included RCTs: maintenance psychotherapy vs. ADM 35 -- 5.2.3 Results of included RCTs: psychotherapy vs. ADM in adults with MDD, acute phase treatment 37 -- 5.2.4 Results of included RCTs: psychotherapy vs. ADM in adults who had had MDD, maintenance treatment 38 -- 5.3 CONCLUSIONS: MAIN PSYCHOTHERAPY INTERVENTIONS ONLY VS. ANTIDEPRESSANTS 39 -- 6 RESULTS RESEARCH QUESTION THREE 39 -- 6.1 SYSTEMATIC REVIEWS 39 -- 6.2 RCTS 39 -- 6.2.1 Characteristics of included RCTs: combined psychotherapy and ADM (acute phase) vs. psychotherapy 39 -- 6.2.2 Characteristics of included RCTs: combined psychotherapy and ADM (acute phase) vs. ADM 41 -- 6.2.3 Characteristics of included RCTs: maintenance combined psychotherapy and ADM vs. maintenance psychotherapy 44 -- 6.2.4 Characteristics of included RCTs: maintenance combined psychotherapy and ADM vs. maintenance ADM 44 -- 6.2.5 Results of included RCTs: combined psychotherapy and ADM vs. psychotherapy in adults with MDD, acute phase treatment 46 -- 6.2.6 Results of included RCTs: combined psychotherapy and ADM vs. ADM in adults with MDD, acute phase treatment 47 -- 6.2.7 Results of included RCTs: combined psychotherapy with ADM vs. psychotherapy in adults who had had MDD, maintenance treatment 48 -- 6.2.8 Results of included RCTs: combined psychotherapy with ADM vs. ADM in adults who had had MDD, maintenance treatment 48 -- 6.3 CONCLUSIONS: MAIN PSYCHOTHERAPY INTERVENTIONS COMBINED WITH ANTIDEPRESSANTS VS. MAIN PSYCHOTHERAPY INTERVENTION OR ANTIDEPRESSANTS ONLY 49 -- 6.4 DISCUSSION 49 -- 7 OTHER CONSIDERATIONS 52 -- 7.1 BALANCE BETWEEN BENEFITS AND HARMS 52 -- 7.1.1 Side effects associated with anti-depressants 52 -- 7.1.2 Side-effects associated with psychotherapy 52 -- 7.2 QUALITY OF THE EVIDENCE 53 -- 7.3 COSTS (RESOURCE ALLOCATION) 53 -- 7.4 PATIENT VALUES AND PREFERENCES 53 -- 8 RECOMMENDATIONS 55 -- 8.1 PSYCHOTHERAPY ALONE, OR IN COMBINATION WITH ANTIDEPRESSANTS 55 -- 9 IMPLEMENTATION AND UPDATING OF THE GUIDELINE 58 -- 9.1 STAKEHOLDER INVOLVEMENT 58 -- 9.1.1 Consensus on recommendations 58 -- 9.1.2 Facilitators and barriers as identified by stakeholders 58 -- 9.2 DISSEMINATION AND IMPLEMENTATION 60 -- 9.3 MONITORING THE QUALITY OF CARE 60 -- 9.4 GUIDELINE UPDATE 60 -- APPENDICES 61 -- APPENDIX 1. DEFINITIONS OF TYPES OF PSYCHOTHERAPY FOR ADULT DEPRESSION11 61 -- REFERENCES 63 Link for e-copy: https://doi.org/10.57598/R230C Format of e-copy: PDF (634 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3442 Copies(0)
Status No copy The long-term efficacy of psychotherapy, alone or in combination with antidepressants, in the treatment of adult major depression / Eirini Karyotaki / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2014)
Copies(0)
Status No copy The long-term efficacy of psychotherapy, alone or in combination with antidepressants, in the treatment of adult major depression / Eirini Karyotaki / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2014)
The long-term efficacy of psychotherapy, alone or in combination with antidepressants, in the treatment of adult major depression : Appendix [printed text] / Eirini Karyotaki, Author ; Yolba Smit, Author ; Pim Cuijpers, Author ; Monique Debauche, Author ; Tom De Keyser, Author ; Hilde Habraken, Author ; William Pitchot, Author ; Filip Reas, Author ; Dominique Salomez, Author ; Benoit Gillain, Author ; Nicolas Fairon , Author ; Dominique Paulus , Author ; Jo Robays, Author ; Kirsten Holdt Henningsen, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2014 . - 195 p. : ill., ; A4. - (KCE Reports. Good Clinical Practice (GCP); 230S) .
ISSN : D/2014/10.273/73 : € 0,00
Study 2013-20
Languages : English (eng)
Descriptors: Indexation
2013-20 ; Antidepressive Agents ; Depression ; Guideline [Publication Type] ; Psychotherapy ; R230
Classification
WM 171.5 Depression. Depressive disorderContents note: APPENDIX REPORT 1 -- TABLE OF CONTENTS 1 -- LIST OF FIGURES 3 -- LIST OF TABLES 5 -- 1. COMPOSITION OF THE GUIDELINE DEVELOPMENT GROUP 7 -- 1.1. COMPOSITION OF THE GUIDELINE DEVELOPMENT GROUP 7 -- 1.2. COMPOSITION OF THE KCE EXPERT TEAM 8 -- 1.3. RESEARCHERS INVOLVED IN THE GUIDELINE 8 -- 2. SEARCH STRATEGIES 9 -- 2.1. TREATMENT: SEARCH STRATEGIES FOR SYSTEMATIC REVIEWS AND META-ANALYSES 9 -- 2.2. TREATMENT: SEARCH STRATEGIES FOR RCTS 22 -- 2.3. PATIENT PREFERENCES: SEARCH STRATEGIES FOR SYSTEMATIC REVIEWS 34 -- 2.3.1. PICO 34 -- 2.3.2. Medline @ Ovid 35 -- 2.3.3. @ Pubmed 40 -- 2.3.4. Embase @ Embase.com 48 -- 2.3.5. PsychINFO @ Ovid 52 -- 2.3.6. Cochrane 58 -- 3. STUDY SELECTION 64 -- 4. QUALITY APPRAISAL 66 -- 4.1. QUALITY APPRAISAL TOOLS 66 -- 4.1.1. Systematic reviews 66 -- 4.1.2. RCTs 69 -- 5. EVIDENCE TABLES 77 -- 5.1. RESEARCH QUESTION 1 77 -- 5.2. RESEARCH QUESTION 2 107 -- 5.3. RESEARCH QUESTION 3 126 -- 6. SUMMARY OF FINDINGS TABLES 147 -- 7. FOREST PLOTS 158 -- 8. SUBGROUP ANALYSIS COGNITIVE BEHAVIOURAL THERAPY 175 -- 9. CONSULTATION OF STAKEHOLDERS 179 -- 9.1. EVALUATION OF THE RECOMMENDATIONS 179 -- 9.1.1. KCE GCP on major depression: Stakeholder survey results 179 -- 9.1.2. Survey Psytoyens 183 -- REFERENCES 189 Link for e-copy: https://doi.org/10.57598/R230S Format of e-copy: PDF (1,77 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3444 Copies(0)
Status No copy