Een nationale praktijkrichtlijn voor de aanpak van cervixkanker [printed text] / Ignace Vergote, Author ; Joan Vlayen  , Author ; Jo Robays, Author ; Sabine Stordeur, Author ; Daphne Stemkens, Author ; Yolba Smit, Author ; Claire Bourgain, Author ; Jacques De Greve, Author ; Frédéric Kridelka, Author ; Pierre Scalliet, Author ; Philippe Simon, Author ; Sigrid Stroobandts, Author ; Peter Van Dam, Author ; Erik Van Limbergen, Author ; Geert Villeirs, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2011 . - IX, 209 p. : ill. ; A4. - ( KCE Reports A. Good Clinical Practice (GCP); 168A) . ISSN : D/2011/10.273/69 : € 0,00 Studie nr. 2010-20 Languages : Dutch ( dut) English ( eng)
| Descriptors: |
Classification
WP 480 Cervix Uteri. Cervix Diseases -- Neoplasms
Indexation
2010-20 ; Cervical Intraepithelial Neoplasia ; Fertility ; Neoplasm Metastasis ; Practice Guideline [Publication type] ; R168 ; Uterine Cervical Neoplasms
|
| Abstract: |
Het Federaal Kenniscentrum voor de Gezondheidszorg (KCE) ontwikkelde samen met het College voor Oncologie een nieuwe kankerrichtlijn, deze keer voor de diagnose, behandeling en opvolging van baarmoederhalskanker. Deze richtlijn is gebaseerd op een systematisch nazicht van de wetenschappelijke literatuur en hierdoor een Belgische primeur. De richtlijn heeft ook aandacht voor de kinderwens en het seksueel functioneren van de getroffen vrouwen. In 2008 werd er nog bij meer dan 600 vrouwen cervixkanker vastgesteld, en bijna 200 vrouwen overleden eraan. |
| Contents note: |
1. INTRODUCTION 6 -- 1.1. SCOPE 6 -- 1.2. EPIDEMIOLOGY 6 -- 2. METHODOLOGY 6 -- 2.1. GENERAL APPROACH 6 -- 2.2. CLINICAL QUESTIONS 6 -- 2.3. INTERNATIONAL COLLABORATION 7 -- 2.4. LITERATURE SEARCHES 7 -- 2.4.1. Search strategy 7 -- 2.4.2. Quality appraisal 8 -- 2.5. DATA EXTRACTION AND SUMMARY 9 -- 2.6. FORMULATION OF RECOMMENDATIONS 9 -- 2.7. EXTERNAL EXPERT MEETING 9 -- 3. FINAL RECOMMENDATIONS 10 -- 3.1. TREATMENT OF HIGH-GRADE CIN 10 -- 3.1.1. Treatment of CIN2/3 10 -- 3.1.2. Follow up of CIN2/3 13 -- 3.1.3. Role of HPV testing in the follow up after treatment 13 -- 3.1.4. Conclusions 13 -- 3.1.5. Recommendations 14 -- 3.2. DIAGNOSIS AND STAGING OF INVASIVE CERVICAL CANCER 15 -- 3.2.1. FIGO staging 15 -- 3.2.2. Tumour characteristics 16 -- 3.2.3. Lymph node metastases 19 -- 3.2.4. Surgical lymph node staging 24 -- 3.2.5. Distant metastases 25 -- 3.2.6. Global staging accuracy 25 -- 3.2.7. Tumour markers 26 -- 3.2.8. Histopathology 26 -- 3.2.9. Recommendations 27 -- 3.3. TREATMENT OF FIGO STAGE IA CERVICAL CANCER 27 -- 3.3.1. Recommendations 29 -- 3.4. TREATMENT OF NON-METASTATIC CERVICAL CANCER 29 -- 3.4.1. Stage IB1 and IIA1 29 -- 3.4.2. Recommendations 31 -- 3.4.3. Stage IB2, IIA2, IIB, IIIA, IIIB and IVA 31 -- 3.5. MANAGEMENT OF METASTATIC AND RECURRENT DISEASE 36 -- 3.5.1. Surgery 36 -- 3.5.2. Chemotherapy for recurrent and stage IVB 37 -- 3.6. FERTILITY-SPARING TREATMENT 39 -- 3.6.1. Conization 39 -- 3.6.2. Radical vaginal trachelectomy 39 -- 3.6.3. Abdominal radical trachelectomy 40 -- 3.6.4. Fertility-sparing treatment according to tumour size 40 -- 3.6.5. Experimental protocols 41 -- 3.7. TREATMENT OF INVASIVE CANCER DURING PREGNANCY 42 -- 3.8. SEXUAL MORBIDITY AFTER TREATMENT FOR CERVICAL CANCER 43 -- 3.9. FOLLOW-UP AFTER TREATMENT FOR CERVICAL CANCER 45 -- 3.9.1. Follow-up after primary treatment 45 -- 3.9.2. PET for the detection of (local or distant) cervical carcinoma recurrence 45 -- 3.9.3. SCCA for the detection of cervical carcinoma recurrence 46 -- 3.9.4. Vaginal smear for the detection of cervical carcinoma recurrence 47 -- 3.9.5. Recommendations 47 -- 4. APPENDICES 48 -- 4.1. APPENDIX 1: GRADE SYSTEM 48 -- 4.1.1. Levels of evidence 190 48 -- 4.1.2. Down- or upgrading the evidence 191 49 -- 4.1.3. Strength of recommendations 50 -- 4.2. APPENDIX 2: SEARCH STRATEGY 50 -- 4.2.1. OVID Medline 50 -- 4.2.2. PubMed 54 -- 4.2.3. Embase 57 -- 4.3. APPENDIX 3: QUALITY APPRAISAL OF GUIDELINES 67 -- 4.4. APPENDIX 4: QUALITY APPRAISAL CHECKLISTS COCANCPG 70 -- 4.4.1. Systematic reviews 70 -- 4.4.2. Randomised controlled trials 70 -- 4.4.3. Cohort studies 70 -- 4.4.4. Case-control studies 70 -- 4.4.5. Diagnostic accuracy studies 71 -- 4.5. APPENDIX 5: EXTERNAL EXPERT REVIEW 72 -- 4.6. APPENDIX 6: EVIDENCE TABLES 77 -- 4.6.1. Guidelines 77 -- 4.6.2. Additional evidence 91 -- 5. REFERENCES 200 |
| Link for e-copy: |
https://doi.org/10.57598/R168A |
| Format of e-copy: |
PDF [Open Access](2,81 Mb) |
| Record link: |
https://kce.docressources.info/index.php?lvl=notice_display&id=2835 |
|  |
Add the result to your basket Make a suggestion Refine your search Apply to external sourcesCancer de l’ovaire / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2016)
EORTC-GCG process quality indicators for ovarian cancer surgery in European journal of cancer, 45(2009)04 ([03/01/2009])
