Author A.A. Mamun
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Adult obesity and number of years lived with and without cardiovascular disease / M.C. Pardo Silva in Obesity, 14(2006)7 ([07/01/2006])
[article] Adult obesity and number of years lived with and without cardiovascular disease [printed text] / M.C. Pardo Silva, Author ; Chris De Laet , Author ; W.J. Nusselder, Author ; A.A. Mamun, Author ; A. Peeters, Author . - 2006 . - 1264-73.
Languages : English (eng)
in Obesity > 14(2006)7 [07/01/2006] . - 1264-73
W 1 Serials. Periodicals
Aging ; Body Mass Index ; Cardiovascular diseases ; Cost of Illness ; Female ; Humans ; Journal Article ; Life Expectancy ; Male ; Middle Aged ; Myocardial infarction ; Obesity ; Overweight ; Peer Review ; Risk Assessment ; Risk Factors ; Stroke ; Time Factors ; United States
Abstract: OBJECTIVE: To determine the differences in number of years lived free of cardiovascular disease (CVD) and number of years lived with CVD between men and women who were obese, pre-obese, or normal weight at 45 years of age.
RESEARCH METHODS AND PROCEDURES: We constructed multistate life tables for CVD, myocardial infarction, and stroke, using data from 2551 enrollees (1130 men) in the Framingham Heart Study who were 45 years of age.
RESULTS: Obesity and pre-obesity were associated with fewer number of years free of CVD, myocardial infarction, and stroke and an increase in the number of years lived with these diseases. Forty-five-year-old obese men with no CVD survived 6.0 years [95% confidence interval (CI), 4.1; 8.1] fewer than their normal weight counterparts, whereas, for women, the difference between obese and normal weight subjects was 8.4 years (95% CI: 6.2; 10.8). Obese men and women lived with CVD 2.7 (95% CI: 1.0; 4.4) and 1.4 years (95% CI: -0.3; 3.2) longer, respectively, than normal weight individuals.
DISCUSSION: In addition to reducing life expectancy, obesity before middle age is associated with a reduction in the number of years lived free of CVD and an increase in the number of years lived with CVD. Such information is paramount for preventive and therapeutic decision-making by individuals and practitioners alike.
Link for e-copy: http://www.nature.com/oby/journal/v14/n7/pdf/oby2006144a.pdf Format of e-copy: PDF [Open Access] (Embargo 2 years) Record link: [article]