[Economic evaluation of antiviral treatment of chronic hepatitis B in Belgium] : Part 2 [printed text] / Christoph Schwierz, Author ; Nancy Thiry, Author ; Stefaan Van de Sande  , Author ; Mohamed Gamil, Author ; Frederik Nevens, Author ; Isabelle Colle, Author ; Yvres Horsmans, Author ; Frank Hulstaert, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2011. - ( KCE Reports. Health Technology Assessment (HTA); 157) . Study n° 2008-11 HTA Chronic hep B Languages : English ( eng)
| Descriptors: |
Indexation
2008-11 ; Antiviral Agents ; Cost-Benefit Analysis ; Hepatitis B virus ; Hepatitis B, Chronic ; R157
Classification
WC 536 Human viral hepatitis
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| Contents note: |
GLOSSARY 2 -- 1 BACKGROUND AND OBJECTIVES 3 -- 1.1 NATURAL HISTORY AND EPIDEMIOLOGY 3 -- 1.2 TREATMENT 4 -- 1.3 OBJECTIVES AND CONTENT OF THE TWO REPORTS 5 -- 2 METHODS 7 -- 2.1 TARGET POPULATION 7 -- 2.2 MODEL STRUCTURE AND BASIC ASSUMPTIONS 7 -- 2.3 TRANSITION PROBABILITIES 9 -- 2.4 DISEASE MANAGEMENT AND TREATMENT COSTS 12 -- 2.5 UTILITIES 13 -- 2.6 ANTIVIRAL TREATMENT 14 -- 3 RESULTS 16 -- 3.1 MODEL VALIDATION: NATURAL EVOLUTION OF DISEASE WITHIN EUROPEAN -- COHORTS 17 -- 3.2 HEALTH OUTCOMES 18 -- 3.2.1 Life-years gained in the three cohorts 18 -- 3.2.2 Undiscounted life-years gained in DC and HCC 19 -- 3.2.3 Mean tenofovir treatment duration in CHB e+ vs e- cohorts 20 -- 3.3 BASE-CASE COST-UTILITY ANALYSES 20 -- 3.3.1 Overview of the results for the three base-case cohorts 20 -- 3.3.2 CHBe+ non-cirrhotic Europeans 21 -- 3.3.3 CHBe- non-cirrhotic Europeans 23 -- 3.3.4 Patient with compensated liver cirrhosis 25 -- 3.4 SCENARIO AND PROBABILISTIC SENSITIVITY ANALYSES 27 -- 3.4.1 Probabilistic sensitivity analysis 27 -- 3.4.2 ICERs in function of the time horizon 30 -- 3.4.3 Asian cohorts 31 -- 3.4.4 Variations in the discount rates 32 -- 3.5 BUDGET IMPACT 33 -- 4 DISCUSSION AND CONCLUSIONS 34 -- 5 APPENDICES 37 -- 5.1 NATURAL PROGRESSION TO LIVER CIRRHOSIS IN 278 CHRONIC HEPATITIS B -- PATIENTS OF EUROPEAN ORIGIN, THE IMPORTANCE OF AGE AND ELEVATED ALT . 37 -- 5.1.1 Introduction 37 -- 5.1.2 Aim 37 -- 5.1.3 Methods 37 -- 5.1.4 Results 38 -- 5.1.5 Discussion and Conclusion 39 -- 5.2 COMPARISON OF PUBLISHED QUALITY OF LIFE DATA 40 -- 5.2.1 Aims 40 -- 5.2.2 Methods 41 -- 5.2.3 Results 43 -- 5.3 DISEASE MANAGEMENT COSTS 46 -- 5.3.1 Data sources 48 -- 5.3.2 Primary inclusion counts 52 -- 5.3.3 Exclusions and sub grouping for cost study 53 -- 5.3.4 Extrapolations for partial lump sum remunerations 59 -- 5.3.5 Results 66 -- 5.3.6 Discussion 72 -- 6 REFERENCES 74 |
| Link for e-copy: |
https://kce.fgov.be/publication/report/economic-evaluation-of-antiviral-treatmen [...] |
| Format of e-copy: |
Webpage |
| Record link: |
https://kce.docressources.info/index.php?lvl=notice_display&id=2584 |
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Add the result to your basket Make a suggestion Refine your search Apply to external sourcesAllgemeine Gynäkologie. Frauenheilkunde und Geburtshilfe in Deutschland – eine Marktübersicht im akutstationären Sektor in Geburtshilfe und Frauenheilkunde, 69(2009)2 ([02/01/2009])
Demand, Selection and Patient Outcomes in German Acute Care Hospitals / Essen [Germany] : Rheinisch-Westfälisches Institut für Wirtschaftsforschung (2008)
