[article] Cost-effectiveness of seasonal influenza vaccination in pregnant women, health care workers and persons with underlying illnesses in Belgium [printed text] / Adriaan Blommaert, Author ; J Bilcke, Author ; Yannick Vandendijck, Author ; Germaine Hanquet, Author ; Niel Hens, Author ; Philippe Beutels, Author . - 2014 . - 6075-6083. Languages : English ( eng) in Vaccine > 32(2014)46 [10/21/2014] . - 6075-6083
| Descriptors: |
Classification
W 1 Serials. Periodicals
Indexation
2010-02-2 ; Belgium ; Health Personnel ; Influenza Vaccines ; Journal Article ; Models, Econometric ; Peer Review ; R204 ; Risk
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| Abstract: |
Risk groups with increased vulnerability for influenza complications such as pregnant women, persons with underlying illnesses as well as persons who come into contact with them, such as health care workers, are currently given priority (along with other classic target groups) to receive seasonal influenza vaccination in Belgium. We aimed to evaluate this policy from a health care payer perspective by cost-effectiveness analysis in the three specific target groups above, while accounting for effects beyond the target group. Increasing the coverage of influenza vaccination is likely to be cost-effective for pregnant women (median euro6589 per quality-adjusted life-year (QALY) gained [euro4073-euro10,249]) and health care workers (median euro24,096/QALY gained [euro16,442-euro36,342]), if this can be achieved without incurring additional administration costs. Assuming an additional physician's consult is charged to administer each additional vaccine dose, the cost-effectiveness of vaccinating pregnant women depends strongly on the extent of its impact on the neonate's health. For health care workers, the assumed number of preventable secondary infections has a strong influence on the cost-effectiveness. Vaccinating people with underlying illnesses is likely highly cost-effective above 50 years of age and borderline cost-effective for younger persons, depending on relative life expectancy and vaccine efficacy in this risk group compared to the general population. The case-fatality ratios of the target group, of the secondary affected groups and vaccine efficacy are key sources of uncertainty. |
| Link for e-copy: |
http://dx.doi.org/10.1016/j.vaccine.2014.08.085 |
| Format of e-copy: |
VDIC IP recognition |
| Record link: |
https://kce.docressources.info/index.php?lvl=notice_display&id=3701 |
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Add the result to your basket Make a suggestion Refine your search Apply to external sourcesCost-effectiveness analysis of rotavirus vaccination of Belgian infants / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2007)
Cost-effectiveness of seasonal influenza vaccination in pregnant women, health care workers and persons with underlying illnesses in Belgium in Vaccine, 32(2014)46 ([10/21/2014])
