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Drug substitution associated with a hospital stay in Belgium / Simoens, Steven in International Journal of Pharmacy Practice, 22(2014)02 ([04/01/2014])  

[article] Drug substitution associated with a hospital stay in Belgium : a retrospective analysis of a claims database [printed text] / Simoens, Steven, Author ; Cécile Dubois , Author ; A. Spinewine, Author ; Veerle Foulon, Author ; Dominique Paulus , Author . - 2014 . - 105-111. Languages : English (eng) in International Journal of Pharmacy Practice > 22(2014)02 [04/01/2014] . - 105-111 Descriptors: Indexation 2009-04 ; Continuity of Patient Care ; Hospitals ; Medication Errors ; Primary Health Care ; R131 ; Seamless Care Abstract: OBJECTIVES: This study measures the extent of drug substitution associated with a hospital stay in Belgium. METHODS: Data were extracted from the 2006-2007 dataset of the Belgian Agency of Health Insurance Funds on drug use of patients hospitalized in acute hospitals. Reimbursed drugs received in ambulatory care during the 3 months prior to hospitalization were compared with drugs received during the 3 months following hospital discharge. Both a narrow definition and a broad definition were used for drug substitution. Narrow substitution (switches between generic and originator drugs) was computed for 14 drug classes for chronic conditions with the highest public expenditure. Broad substitution (changes between chemical substances within the drug class at ATC level 4, changes in brand name) was calculated for statins and proton-pump inhibitors only. KEY FINDINGS: The database included 17 764 patients (mean age 66 ± 17 years; 60% female). In 71% of cases an originator drug was received prior to and following hospitalization. A generic drug was received prior to and following hospitalization in 25% of cases. Some form of narrow substitution occurred in 4% of cases: a generic drug was replaced by an originator drug in 2% of cases and an originator drug was replaced by a generic drug in 2% of cases. Some form of broad substitution occurred in 25% of cases for proton-pump inhibitors and 13% of cases for statins. CONCLUSIONS: Hospitalization was not a trigger for changes between originator and generic versions of a drug. Broad substitution associated with a hospital stay was relatively limited for statins and proton-pump inhibitors. Link for e-copy: http://dx.doi.org/10.1111/ijpp.12048 Format of e-copy: PDF [Requires Subscription) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3678 [article]

Geneesmiddelen gebruik in de Belgische rusthuizen en rust- en verzorgingstehuizen / Robert H. Vander Stichele / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2006)  

Geneesmiddelen gebruik in de Belgische rusthuizen en rust- en verzorgingstehuizen [printed text] / Robert H. Vander Stichele, Author ; Carine Van de Voorde, Author ; Th Christiaens, Author ; M Bauwens, Author ; M De Falleur, Author ; M Gobert, Author ; A. Somers, Author ; E. Mehuys, Author ; T De Floor, Author ; P Chevalier, Author ; Petrovic, M, Author ; M. Smet, Author ; K. Soenen, Author ; C. Verrue, Author ; MM Elseviers, Author ; Stephan Devriese ; Dirk Ramaekers ; A. Spinewine, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2006 . - Viii, 196 p. : ill. ; 30 cm.. - (KCE Reports A. Health Services Research (HSR); 47A) . ISSN : D/2006/10.273/61 : 0 € Languages : Dutch (dut) Descriptors: Classification WT 27 Hospitals, dispensaries, clinics, old age homes, etc -- Collective Indexation 2005-17 ; Drug Utilization ; Health Care Costs ; Health Services Research ; Homes for the Aged ; Pharmaceutical Services ; Quality Assurance, Health Care ; R47 Link for e-copy: https://doi.org/10.57598/R47A Format of e-copy: PDF Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=748

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Medication use in rest and nursing homes in Belgium / Robert H. Vander Stichele / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2006)  

Medication use in rest and nursing homes in Belgium [printed text] / Robert H. Vander Stichele, Author ; Carine Van de Voorde, Author ; Th Christiaens, Author ; M Bauwens, Author ; M De Falleur, Author ; M Gobert, Author ; A. Somers, Author ; E. Mehuys, Author ; T De Floor, Author ; P Chevalier, Author ; Petrovic, M, Author ; M. Smet, Author ; K. Soenen, Author ; C. Verrue, Author ; MM Elseviers, Author ; Stephan Devriese , Author ; Dirk Ramaekers, Author ; A. Spinewine, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2006 . - vii, 12 p. : ill. ; 30 cm.. - (KCE Reports. Health Services Research (HSR); 47C) . ISSN : D/2006/10.273/70 : 0 € Study nr 2005-17 Languages : English (eng) Descriptors: Classification WT 27 Hospitals, dispensaries, clinics, old age homes, etc -- Collective Indexation 2005-17 ; Drug Utilization ; Health Care Costs ; Health Services Research ; Homes for the Aged ; Pharmaceutical Services ; Quality Assurance, Health Care ; R47 Link for e-copy: https://doi.org/10.57598/R47C Format of e-copy: .PDF (1,36 MB) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=1632

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Review of the cost-effectiveness of interventions to improve seamless care focusing on medication / Simoens, Steven in International journal of clinical pharmacy, 33(2011)06 ([12/01/2011])  

[article] Review of the cost-effectiveness of interventions to improve seamless care focusing on medication [printed text] / Simoens, Steven, Author ; A. Spinewine, Author ; Veerle Foulon, Author ; Dominique Paulus , Author . - 2011 . - p. 909-917. Languages : English (eng) in International journal of clinical pharmacy > 33(2011)06 [12/01/2011] . - p. 909-917 Descriptors: Classification W 1 Serials. Periodicals Indexation administration and dosage ; Continuity of Patient Care ; Cost-Benefit Analysis ; Costs and Cost Analysis ; drug therapy ; Health Care Costs ; Journal Article ; Peer Review ; Pharmaceutical Preparations ; Quality Assurance, Health Care ; Quality of Life ; Research Design Contents note: AIM OF THE REVIEW: This review of the international literature aims to assess the evidence and its methodological quality relating to the cost-effectiveness of interventions to improve seamless care focusing on medication. METHOD: Studies were identified by searching Medline, EMBASE, Centre for Reviews and Dissemination databases, Cochrane Database of Systematic Reviews, and EconLit up to March 2011 using search terms related to health economics and to seamless care. To be included, economic evaluations had to explore the costs and consequences of an intervention to improve seamless care focusing on medication as compared with usual care. Methodological quality of studies was assessed by considering perspective; design; source of clinical and economic data; cost and consequence measures; allowance for uncertainty; and incremental analysis. Costs were actualized to 2007 values. RESULTS: Eight studies on medication interventions for hospitalized patients in the transition between ambulatory and hospital care were included in the review. A variety of types of medication interventions and target populations have been assessed, but the evidence is limited to one economic evaluation for each particular intervention type and each specific target population. Most studies demonstrated an impact of interventions on compliance and (re)hospitalization rates and costs. The studies did not find an impact on quality of life or symptoms. Economic evaluations suffered from methodological limitations related to the narrow perspective; restriction to health care costs only; exclusion of costs of the intervention; use of intermediate consequence measures; no allowance for uncertainty; and absence of incremental analysis. CONCLUSION: In light of the small number of economic evaluations and their methodological limitations, it is not possible to recommend a specific intervention to improve seamless care focusing on medication on health economic grounds. Link for e-copy: https://doi.org/10.1007/s11096-011-9563-5 Format of e-copy: PDF [Requires Subscription] Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4108 [article]

L'utilisation des médicaments dans les maisons de repos et les maisons de repos et de soins belges / Robert H. Vander Stichele / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2006)  

L'utilisation des médicaments dans les maisons de repos et les maisons de repos et de soins belges [printed text] / Robert H. Vander Stichele, Author ; Carine Van de Voorde, Author ; Th Christiaens, Author ; M Bauwens, Author ; M De Falleur, Author ; M Gobert, Author ; A. Somers, Author ; E. Mehuys, Author ; T De Floor, Author ; P Chevalier, Author ; Petrovic, M, Author ; M. Smet, Author ; K. Soenen, Author ; C. Verrue, Author ; MM Elseviers, Author ; Stephan Devriese , Author ; Dirk Ramaekers, Author ; A. Spinewine, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2006 . - ix, 196 p. : ill. ; 30 cm.. - (KCE Reports B. Health Services Research (HSR); 47B) . ISSN : D/2006/10.273/62 : 0 € Languages : French (fre) Descriptors: Classification WT 27 Hospitals, dispensaries, clinics, old age homes, etc -- Collective Indexation 2005-17 ; Drug Utilization ; Health Care Costs ; Health Services Research ; Homes for the Aged ; Pharmaceutical Services ; Quality Assurance, Health Care ; R47 Link for e-copy: https://doi.org/10.57598/R47B Format of e-copy: PDF Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=719

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