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Seasonal influenza vaccination: prioritizing children or other target groups? / Philippe Beutels / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)
Seasonal influenza vaccination: prioritizing children or other target groups? : Part II: cost-effectiveness analysis - Supplement [printed text] / Philippe Beutels, Author ; Yannick Vandendijck, Author ; Lander Willem, Author ; Nele Goeyvaerts, Author ; Adriaan Blommaert, Author ; Kim van Kerckhove, Author ; J Bilcke, Author ; Germaine Hanquet, Author ; P. Neels, Author ; Nancy Thiry, Author ; Jori Liesenborgs, Author ; Niel Hens, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2013 . - 111 p. : Ill. ; A4. - (KCE Reports. Health Technology Assessment (HTA); 204S1v1) .
ISSN : D/2013/10.273/44 : € 0,00
Study 2010-02 HTA VZV Vaccination
Languages : English (eng)
Descriptors: Indexation
2010-02-2 ; Adolescent ; Aged ; Child ; Child, Preschool ; Comorbidity ; Cost-Benefit Analysis ; Costs and Cost Analysis ; Health Personnel ; Infant ; Influenza Vaccines ; Influenza, Human ; Middle Aged ; Pregnancy ; R204 ; Young Adult
Classification
WC 515 Human influenzaContents note: 1. REVIEW DETAILS OF EFFICACY AND EFFECTIVENESS STUDIES 7 -- 1.1. INFLUENZA VACCINE EFFICACY IN CHILDREN 7 -- 1.1.1. Live Attenuated Influenza Vaccine (LAIV) studies in children based on EPAR 7 -- 1.1.2. Published data on LAIV & TIV in children 15 -- 1.2. INFLUENZA VACCINE EFFICACY IN HEALTHY ADULTS 21 -- 2. SELECTION OF QUALITY OF LIFE STUDIES FOR REVIEW 24 -- 2.1. SEARCH STRATEGY FOR QUALITY OF LIFE STUDIES 24 -- 2.2. CATEGORISATION AND SELECTION OF QUALITY OF LIFE STUDIES 25 -- 3. COST DATA 27 -- 3.1. LIST OF COMORBIDITIES COMBINED WITH A DIAGNOSIS OF INFLUENZA 27 -- 3.2. LIST OF PREGNANCY COMPLICATIONS 30 -- 3.3. IN-HOSPITAL COSTS FOR HOSPITALIZED INFLUENZA PATIENTS 37 -- 3.3.1. Aggregated data on in-hospital cost for hospitalised influenza patients 37 -- 3.3.2. Disaggregated data on in-hospital cost for hospitalised influenza patients 63 Link for e-copy: http://doi.org/10.57598/R204S1.1 Format of e-copy: PDF (4,6 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3236 Copies(0)
Status No copy Seasonal influenza vaccination: prioritizing children or other target groups? / Philippe Beutels / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)
Seasonal influenza vaccination: prioritizing children or other target groups? : Part II: cost-effectiveness analysis - Supplement [printed text] / Philippe Beutels, Author ; Yannick Vandendijck, Author ; Lander Willem, Author ; Nele Goeyvaerts, Author ; Adriaan Blommaert, Author ; Kim van Kerckhove, Author ; J Bilcke, Author ; Germaine Hanquet, Author ; P. Neels, Author ; Nancy Thiry, Author ; Jori Liesenborgs, Author ; Niel Hens, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2013 . - 205 p. : Ill. ; A4. - (KCE Reports. Health Technology Assessment (HTA); 204S1v2) .
ISSN : D/2013/10.273/45 : € 0,00
Study 2010-02 HTA VZV Vaccination
Languages : English (eng)
Descriptors: Indexation
2010-02-2 ; Adolescent ; Aged ; Child ; Child, Preschool ; Comorbidity ; Cost-Benefit Analysis ; Costs and Cost Analysis ; Health Personnel ; Infant ; Influenza Vaccines ; Influenza, Human ; Middle Aged ; Pregnancy ; R204 ; Young Adult
Classification
WC 515 Human influenzaContents note: 4. DYNAMIC TRANSMISSION MODEL: ADDITIONAL RESULTS 13 -- 4.1. MODIFIED CHILDREN OPTIONS + CURRENT ADULT VACCINATION (AVERAGE WANING -- IMMUNITY FIXED AT 1.68 YEARS) 13 -- 4.1.1. Effectiveness versus current situation 13 -- 4.1.2. Incremental analyses 31 -- 4.2. MODIFIED CHILDREN OPTIONS + CURRENT ADULT VACCINATION (WANING IMMUNITY FIXED -- AT AN AVERAGE OF 6 YEARS) 40 -- 4.2.1. Effectiveness versus current situation 40 -- 4.2.2. Cost-effectiveness versus current situation 58 -- 4.3. MODIFIED CHILDREN OPTIONS + MODIFIED ADULT VACCINATION TARGETS (WANING -- IMMUNITY FIXED AT AN AVERAGE OF 1.68 YEARS) 77 -- 4.3.1. Effectiveness versus current situation 77 -- 4.3.2. Incremental cost-effectiveness analysis 95 -- 4.4. MODIFIED CHILDREN OPTIONS + MODIFIED ADULT VACCINATION TARGETS (WANING -- IMMUNITY FIXED AT 6 YEARS) 128 -- 4.4.1. Effectiveness versus current situation 128 -- 4.4.2. Incremental cost-effectiveness analysis 146 -- 4.4.3. Sensitivity analysis: identifying the optimal expansion path under decreasing vaccination -- costs in children, with waning immunity of 1/6 years 167 -- 4.5. MODIFIED CHILDREN OPTIONS + MODIFIED ADULT VACCINATION REDUCTION (WANING -- IMMUNITY FIXED AT 1.68 YEARS) 170 -- 4.5.1. Effectiveness versus current situation 170 -- 4.6. MODIFIED CHILDREN OPTIONS + MODIFIED ADULT VACCINATION REDUCTION (WANING -- IMMUNITY FIXED AT 6 YEARS) 188 -- 4.6.1. Effectiveness versus current situation 188 Link for e-copy: http://doi.org/10.57598/R204S1.2 Format of e-copy: PDF (15,3 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3237 Copies(0)
Status No copy Seasonal influenza vaccination: prioritizing children or other target groups? / Philippe Beutels / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)
Seasonal influenza vaccination: prioritizing children or other target groups? : Part II: cost-effectiveness analysis - Supplement [printed text] / Philippe Beutels, Author ; Yannick Vandendijck, Author ; Lander Willem, Author ; Nele Goeyvaerts, Author ; Adriaan Blommaert, Author ; Kim van Kerckhove, Author ; J Bilcke, Author ; Germaine Hanquet, Author ; P. Neels, Author ; Nancy Thiry, Author ; Jori Liesenborgs, Author ; Niel Hens, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2013 . - 29 p. : Ill. ; A4. - (KCE Reports. Health Technology Assessment (HTA); 204S1v3) .
ISSN : D/2013/10.273/46 : € 0,00
Study 2010-02 HTA VZV Vaccination
Languages : English (eng)
Descriptors: Indexation
2010-02-2 ; Adolescent ; Aged ; Child ; Child, Preschool ; Comorbidity ; Cost-Benefit Analysis ; Costs and Cost Analysis ; Health Personnel ; Infant ; Influenza Vaccines ; Influenza, Human ; Middle Aged ; Pregnancy ; R204 ; Young Adult
Classification
WC 515 Human influenzaContents note: 5. STATIC MODEL: ADDITIONAL RESULTS 3 -- 5.1. HCW WITHOUT MARGINAL ADMINISTRATION COSTS 3 -- 5.1.1. HCW aged 20-29 years 3 -- 5.1.2. HCW aged 30-49 years 4 -- 5.1.3. HCW aged 50-65 years 5 -- 5.2. HCW WITH MARGINAL ADMINISTRATION COSTS 14 -- 5.2.1. HCW aged 20-29 years 14 -- 5.2.2. HCW aged 30-49 years 15 -- 5.2.3. HCW aged 50-65 years 16 Link for e-copy: http://doi.org/10.57598/R204S1.3 Format of e-copy: PDF (413 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3238 Copies(0)
Status No copy Seasonal influenza vaccination: prioritizing children or other target groups? / Philippe Beutels / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2013)
Seasonal influenza vaccination: prioritizing children or other target groups? : Part II: cost-effectiveness analysis - Synthesis [printed text] / Philippe Beutels, Author ; Yannick Vandendijck, Author ; Lander Willem, Author ; Nele Goeyvaerts, Author ; Adriaan Blommaert, Author ; Kim van Kerckhove, Author ; J Bilcke, Author ; Germaine Hanquet, Author ; P. Neels, Author ; Nancy Thiry, Author ; Jori Liesenborgs, Author ; Niel Hens, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2013 . - 28 p. : Ill. ; A4. - (KCE Reports. Health Technology Assessment (HTA); 204Cs) .
ISSN : D/2013/10.273/42 : € 0,00
Study 2010-02 HTA VZV Vaccination
Languages : English (eng)
Descriptors: Indexation
2010-02-2 ; Adolescent ; Aged ; Child ; Child, Preschool ; Comorbidity ; Cost-Benefit Analysis ; Costs and Cost Analysis ; Health Personnel ; Infant ; Influenza Vaccines ; Influenza, Human ; Middle Aged ; Pregnancy ; R204 ; Young Adult
Classification
WC 515 Human influenzaContents note: FOREWORD 1 -- ABSTRACT 2 -- SYNTHESIS 4 -- 1. INFLUENZA DISEASE AND VACCINES 6 -- 1.1. INFLUENZA, A COMMON DISEASE BUT A COMPLEX VIRUS 6 -- 1.2. INFLUENZA VACCINES AND POLICIES IN BELGIUM 6 -- 1.3. WHY VACCINATING CHILDREN AGAINST SEASONAL INFLUENZA? 7 -- 1.4. RESEARCH QUESTIONS 7 -- 2. METHODS 8 -- 2.1. VACCINATION OPTIONS 8 -- 2.2. MODELS 8 -- 2.2.1. Dynamic model 9 -- 2.2.2. Static model 9 -- 2.3. ECONOMIC ANALYSIS 9 -- 3. MODEL PARAMETERS AND ASSUMPTIONS 10 -- 3.1. DISEASE BURDEN AND TRANSMISSION 10 -- 3.2. INFLUENZA VACCINES, SAFETY AND IMMUNITY 11 -- 4. COST-EFFECTIVENESS OF SEASONAL INFLUENZA VACCINATION 15 -- 4.1. VACCINATING CHILDREN ONLY 15 -- 4.2. MODIFYING VACCINATION COVERAGE IN ADULTS ONLY 17 -- 4.2.1. By age group 17 -- 4.2.2. In specific target groups 19 -- 4.3. VACCINATING CHILDREN AND MODIFYING COVERAGE IN ADULTS 20 -- 5. DISCUSSION 21 -- 5.1. VACCINATING CHILDREN 21 -- 5.2. CHANGING COVERAGE IN ADULTS WITH OR WITHOUT CHILDHOOD VACCINATION 22 -- 5.3. LIMITATIONS OF THE STUDY 23 -- 5.4. FUTURE PERSPECTIVES 23 -- 6. CONCLUSIONS 24 -- REFERENCES 26 -- RECOMMENDATIONS 28 Link for e-copy: http://doi.org/10.57598/R204CS Format of e-copy: PDF (430 Kb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=3235 Copies(0)
Status No copy Seasonal influenza vaccination / Germaine Hanquet / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2011)
Seasonal influenza vaccination : priority target groups – Part I [printed text] / Germaine Hanquet, Author ; Pascale Jonckheer , Author ; Joan Vlayen , Author ; France Vrijens , Author ; Nancy Thiry, Author ; Philippe Beutels, Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2011 . - XI, 143 p. : ill. ; A4. - (KCE Reports. Good Clinical Practice (GCP); 162C) .
ISSN : D/2011/10.273/45 : € 0,00
Study nr. 2010-02-01
Brussel, 1 June 2012 (2nd print ; 1st print : 14 JUlY 2011)
Languages : English (eng)
Descriptors: Indexation
2010-02-01 ; Aged ; Comorbidity ; Health Personnel ; Influenza Vaccines ; Influenza, Human ; Pregnancy ; R162
Classification
WC 515 Human influenzaContents note: Table of contents -- LIST OF FIGURES 5 -- LIST OF TABLES 6 -- GLOSSARY 9 -- 1 INTRODUCTION 10 -- 1.1 INFLUENZA DISEASE 10 -- 1.2 VACCINES FOR SEASONAL INFLUENZA 10 -- 1.3 SEASONAL INFLUENZA VACCINATION IN BELGIUM 12 -- 2 RESEARCH QUESTIONS13 -- 3 METHODS 14 -- 3.1 TARGET GROUPS AND VACCINATION SCENARIOS 14 -- 3.2 DENOMINATORS 15 -- 3.3 PARAMETERS FOR INFLUENZA SEASONS 15 -- 3.3.1 Influenza seasons and viral activity seasons 15 -- 3.3.2 Matching and season intensity 16 -- 3.4 MODEL 16 -- 3.5 PARAMETERS FOR INFLUENZA OUTCOMES 17 -- 3.5.1 Overall methodological approach 18 -- 3.5.2 Outpatient cases of ILI and confirmed influenza cases 19 -- 3.5.3 Inpatient cases of influenza and/or pneumonia 20 -- 3.5.4 Deaths from influenza and/or pneumonia 20 -- 3.6 PARAMETERS FOR VACCINE EFFECTIVENESS 21 -- 3.7 SENSITIVITY ANALYSIS 22 -- 3.8 ASSUMPTIONS USED 23 -- 4 DETERMINATION OF PARAMETERS 24 -- 4.1 DENOMINATORS 24 -- 4.2 INFLUENZA SEASONS 24 -- 4.3 INFLUENZA BURDEN BY INFLUENZA SEASON 25 -- 4.3.1 Outpatient cases of ILI and confirmed influenza 25 -- 4.3.2 Admissions for influenza and pneumonia 28 -- 4.3.3 Deaths from influenza and pneumonia 33 -- 4.4 INFLUENZA BURDEN DURING VIRAL ACTIVITY SEASONS36 -- 4.5 INFLUENZA VACCINE EFFECTIVENESS (IVE) 37 -- 4.5.1 IVE parameters in healthy adults (15-64 years) 38 -- 4.5.2 IVE parameters in elderly (65 years and above) 40 -- 4.5.3 IVE parameters in 1-64 years with co-morbidities 41 -- 4.5.4 IVE parameters in HCWs 42 -- 4.5.5 IVE parameters in pregnant women 42 -- 5 IMPACT CALCULATIONS 43 -- 5.1 VACCINE NEEDS BY SCENARIO 43 -- 5.2 IMPACT OF EACH VACCINATION SCENARIO IN AN INFLUENZA SEASON 44 -- 5.2.1 Vaccination of persons 1-64 years old with co-morbidities 44 -- 5.2.2 Vaccination of the elderly 65-74 years of age 45 -- 5.2.3 Vaccination of the elderly ≥75 years of age 47 -- 5.2.4 Vaccination of healthy adults 50-64 years 47 -- 5.2.5 Vaccination of HCW 49 -- 5.2.6 Vaccination of pregnant women49 -- 5.2.7 Not vaccinating healthy adults 15-49 years 50 -- 5.3 IMPACT OF EACH VACCINATION SCENARIO IN AN ACTIVITY SEASON 51 -- 5.3.1 Vaccination of persons 1-64 years with co-morbidities 51 -- 5.3.2 Vaccination of the elderly 65-74 years of age 51 -- 5.3.3 Vaccination of the elderly ≥75 years of age 51 -- 5.3.4 Vaccination of healthy adults 50-64 years 51 -- 5.3.5 Vaccination in HCW 51 -- 5.3.6 Vaccination of pregnant women51 -- 5.3.7 Not vaccinating healthy adults 15-49 years 51 -- 5.4 SUMMARY OF IMPACT BY VACCINATION SCENARIO 51 -- 5.5 UNCERTAINTY AND SENSITIVITY ANALYSES 56 -- 6 DISCUSSION 58 -- 7 CONCLUSIONS ON PRIORITY SETTING 61 -- 8 APPENDIX 1: DATA SOURCES AND METHODS TO ESTIMATE MEDICAL -- BURDEN AND UPTAKE 62 -- 8.1 CURRENT VACCINE UPTAKE 62 -- 8.2 INFLUENZA SEASONS 62 -- 8.3 POPULATION FIGURES 63 -- 8.4 OUTPATIENT CASES OF INFLUENZA-LIKE ILLNESS AND INFLUENZA 64 -- 8.4.1 ILI cases reported to the IPH Sentinel Network of GPs 64 -- 8.4.2 ILI laboratory results from the IPH National Influenza Centre 64 -- 8.4.3 Estimation of total ILI and influenza cases 65 -- 8.5 HOSPITAL ADMISSIONS FOR INFLUENZA AND PNEUMONIA 66 -- 8.5.1 Source of data 66 -- 8.5.2 Estimation of admission parameters 67 -- 8.6 DEATHS FROM INFLUENZA AND PNEUMONIA 68 -- 8.6.1 Cause-specific deaths from Flanders, Wallonia and Brussels 68 -- 8.6.2 In hospital deaths from MCD database 68 -- 8.6.3 Estimation of mortality parameters 69 -- 8.7 TARGET GROUP FOR SEASONAL INFLUENZA VACCINATION IN BELGIUM 69 -- 9 APPENDIX 2: RESULTS ON INFLUENZA DISEASE BURDEN 70 -- 9.1 INFLUENZA ACTIVITY SEASONS 70 -- 9.2 POPULATION FIGURES 70 -- 9.3 ILI AND INFLUENZA CASES BY INFLUENZA SEASON 71 -- 9.3.1 Cases reported and swabbed by the network 71 -- 9.3.2 ILI in the Belgian population 72 -- 9.3.3 Influenza in the Belgian population 73 -- 9.4 ADMISSIONS FOR INFLUENZA AND PNEUMONIA BY INFLUENZA SEASON 76 -- 9.4.1 Admissions by age group 76 -- 9.4.2 Admission in healthy adults aged 15-75 years 81 -- 9.4.3 Admissions in persons with co-morbidities 81 -- 9.4.4 Admissions in pregnant women 83 -- 9.4.5 Admissions in HCW 85 -- 9.5 DEATHS FROM INFLUENZA AND PNEUMONIA BY INFLUENZA SEASON 85 -- 9.5.1 Deaths by age group 85 -- 9.5.2 Deaths by co-morbidity status (<75 years) 88 -- 9.5.3 Deaths in pregnancy 90 -- 9.5.4 Deaths in HCW 90 -- 9.6 INFLUENZA BURDEN BY SEASON OF VIRAL ACTIVITY90 -- 9.7 VACCINE UPTAKE 92 -- 10 APPENDIX 3: LITERATURE REVIEW ON BURDEN OF INFLUENZA IN -- SPECIFIC TARGET GROUPS 93 -- 10.1 METHODS 93 -- 10.2 ADULTS WITH UNDERLYING CONDITIONS 93 -- 10.2.1 Outpatient influenza in adults with underlying conditions 93 -- 10.2.2 Hospitalizations in adults with underlying conditions 94 -- 10.2.3 Mortality in adults with underlying conditions 95 -- 10.3 ELDERLY WITH UNDERLYING CONDITIONS 96 -- 10.3.1 Outpatient influenza/ILI in elderly with underlying conditions 96 -- 10.3.2 Hospitalization in elderly with underlying conditions 96 -- 10.3.3 Mortality in elderly with underlying conditions 96 -- 10.4 CHILDREN WITH UNDERLYING CONDITIONS 97 -- 10.4.1 Outpatient influenza/ILI in children with underlying conditions 97 -- 10.4.2 Hospitalization in children with underlying conditions 98 -- 10.4.3 Mortality in children with underlying conditions 99 -- 10.5 PREGNANT WOMEN 100 -- 10.5.1 Outpatient influenza/ILI in pregnant women 100 -- 10.5.2 Hospitalisation in pregnant women 100 -- 10.5.3 Mortality in pregnant women 101 -- 10.5.4 Outcome of the foetus 101 -- 10.6 HEALTH CARE WORKERS 102 -- 10.6.1 Definition of health care workers 102 -- 10.6.2 Outpatient influenza/ILI in health care workers (HCW) 102 -- 10.6.3 Mortality in health care workers 102 -- 10.6.4 Transmission in vulnerable patients 103 -- 11 APPENDIX 4: SELECTION OF PARAMETERS ON INFLUENZA VACCINE -- EFFICACY AND EFFECTIVENESS 104 -- 11.1 METHODS 104 -- 11.1.1 Inclusion criteria for IVE studies 104 -- 11.1.2 Data analysis 104 -- 11.2 IVE PARAMETERS 105 -- 11.2.1 Healthy adults 106 -- 11.2.2 Patients 15-64 years with co-morbidities 109 -- 11.2.3 Elderly (65 years and above) 109 -- 11.2.4 Pregnant women and infants 114 -- 11.2.5 Health care workers 115 -- 11.3 ADDITIONAL DATA VACCINE EFFECTIVENESS/EFFICACY FOR OUTCOME ILI 116 -- 12 APPENDIX 5: LITTERATURE REVIEW ON EFFICACY AND EFFECTIVENESS -- OF INFLUENZA VACCINATION117 -- 12.1 SEARCH STRATEGY 117 -- 12.1.1 Research question 117 -- 12.1.2 Searched databases 117 -- 12.1.3 Search strings and limits 118 -- 12.1.4 Inclusion criteria 118 -- 12.1.5 Quality appraisal and data extraction 118 -- 12.2 HEALTH CARE WORKERS 119 -- 12.2.1 Indirect effect on patients 119 -- 12.2.2 Direct effect on HCW 119 -- 12.3 PERSONS AT HIGH RISK OF INFLUENZA-RELATED COMPLICATIONS120 -- 12.3.1 Chronic respiratory diseases 120 -- 12.3.2 Diabetes 120 -- 12.3.3 Cardiovascular disease 120 -- 12.3.4 Other high-risk populations 120 -- 12.3.5 Patients with any co-morbidities 121 -- 12.4 PREGNANT WOMEN 121 -- 12.5 PERSONS AGED 65 OR MORE122 -- 12.5.1 Systematic reviews 122 -- 12.5.2 Primary studies 123 -- 12.6 HEALTHY ADULTS AGED 18-64 YEARS 124 -- 12.7 SEARCH SYNTAXES 125 -- 12.7.1 OVID Medline 125 -- 12.7.2 EMBASE 128 -- 12.7.3 Cochrane database of systematic reviews and DARE (through Cochrane library) 130 -- 12.7.4 CENTRAL (through Cochrane library) 130 -- 13 APPENDIX 6: DISTRIBUTION OF INPUT PARAMETERS FOR AND RESULTS -- FROM THE UNCERTAINTY ANALYSIS 131 -- 13.1 DISTRIBUTION OF INPUT PARAMETERS 131 -- 13.2 RESULTS OF THE MONTECARLO SIMULATIONS 133 -- 14 REFERENCES 134 Link for e-copy: https://doi.org/10.57598/R162C Format of e-copy: PDF [Open Access] (1,4 MB) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=2647 Copies(0)
Status No copy Les soins informels en Belgique / Maria-Isabel Farfan-Portet / Paris [France] : Centre de Sociologie et de Démographie Médicales (2007)
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PermalinkThe construct and concurrent validity of the EQ-5D in a renal transplant population / Irina Cleemput in Value in Health, 7(2004)4 ([07/01/2004])
PermalinkThe economic impact of using alfuzosin 10 mg once daily in the management of acute urinary retention in the UK / Lieven Annemans in BJU international, 96(2005)4 ([08/01/2005])
PermalinkThe effect of montelukast on rhinitis symptoms in patients with asthma and seasonal allergic rhinitis / George Philip in Current medical research and opinion, 20(2004)10 ([10/01/2004])
PermalinkPermalinkThe significance of activation markers on CD8 lymphocytes in human immunodeficiency syndrome: staging and prognostic value / M. Levacher in Clinical and experimental immunology, 90(1992)3 ([12/01/1992])
PermalinkThe use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women / John A. Kanis, in Osteoporosis international, 19(2008)4 ([04/01/2008])
PermalinkToolkit Heerlijk Helder in de Zorg / Thomas More (2016)
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