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Polyvalent immunoglobulins / Jolyce Bourgeois / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre
Polyvalent immunoglobulins : Part 1: A rapid review [printed text] / Jolyce Bourgeois , Author ; Nicolas Fairon , Author ; Lorena San Miguel , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, [s.d.] . - 129 p. : ill., ; A4. - (KCE Reports. Health Technology Assessment (HTA); 327) .
ISSN : D/2019/10.273/82 : € 0,00
Languages : English (eng)
Descriptors: Indexation
2018-53-01 ; Immune System Diseases ; Immunoglobulins ; Injections, Intravenous ; R327 ; Technology Assessment, Biomedical
Classification
QW 601 ImmunoglobulinsContents note: SCIENTIFIC REPORT 7 -- 1 INTRODUCTION 7 -- 1.1 BACKGROUND 7 -- 1.2 INTERNATIONAL CONTEXT 7 -- 1.4 PROJECT SCOPE .13 -- 2 THE EFFECTIVENESS AND SAFETY OF IMMUNOGLOBULINS BY INDICATION 13 -- 2.1 BACKGROUND 13 -- 2.2 METHODS 14 -- 2.2.1 Overview of general methodology 14 -- 2.2.2 Literature search and selection of indications 17 -- 2.2.3 Quality appraisal and data extraction .18 -- 2.2.4 Assessing efficacy 18 -- 2.2.5 Assessing safety 18 -- 2.3.1 General Safety 21 -- 2.3.2 Indication-specific results - Reimbursed indications 23 -- 2.3.3 Indication-specific results - Commonly recommended indications in other countries 52 -- 2.3.4 Other indications for which evidence exists 66 -- 2.3.5 Ongoing trials .70 -- 3 SYSTEMATIC LITERATURE REVIEW OF ECONOMIC STUDIES 77 -- 3.1 INTRODUCTION .77 -- 3.2 METHODS 77 -- 3.2.1 Search strategy .77 -- 3.2.2 Selection procedure 77 -- 3.2.3 Selection criteria 77 -- 3.3 OVERVIEW OF ECONOMIC EVALUATIONS .80 -- 3.3.1 Type of economic evaluation .81 -- 3.3.2 Time frame of analyses and discounting .81 -- 3.3.3 Perspective .81 -- 3.3.4 Indications and Population 81 -- 3.3.5 Comparators 81 -- 3.3.6 Cost and outcome inputs .82 -- 3.3.7 Modelling 82 -- 3.3.8 Results 83 -- 3.3.9 Sensitivity analysis 91 -- 3.3.10 Conflict of interest 91 -- 3.4 DISCUSSION AND CONCLUSIONS 91 -- 4 HOW DO THE INDICATIONS REIMBURSED IN BELGIUM COMPARE TO INDICATIONS REIMBURSED IN OTHER COUNTRIES? 93 -- 4.1 METHODS 93 -- 4.2 BELGIUM 93 -- 4.3 AUSTRALIA 94 -- 4.4 FRANCE 95 -- 4.5 CANADA 96 -- 4.6 ENGLAND 99 -- 4.7 INTERPRETATION INTERNATIONAL: 100 -- 5 DISCUSSION AND CONCLUSIONS .104 -- 5.1 DISCUSSION .104 -- 5.2 CONCLUSIONS 107 -- REFERENCES 108 Link for e-copy: http://doi.org/10.57598/R327C Format of e-copy: PDF (2,4 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4653 Polyvalent immunoglobulins / Jolyce Bourgeois / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2019)
Polyvalent immunoglobulins : Part 1: A rapid review - Supplement 1 [printed text] / Jolyce Bourgeois , Author ; Nicolas Fairon , Author ; Lorena San Miguel , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2019 . - 198 p. : ill., ; A4. - (KCE Reports. Health Technology Assessment (HTA); 327S1) .
ISSN : D/2019/10.273/83 : € 0,00
Languages : English (eng)
Descriptors: Indexation
2018-53-01 ; Immune System Diseases ; Immunoglobulins ; Injections, Intravenous ; R327 ; Technology Assessment, Biomedical
Classification
QW 601 ImmunoglobulinsContents note: 1 SEARCH STRATEGY 3 -- MEDLINE, EMBASE AND COCHRANE FOR SYSTEMATIC REVIEWS 3 -- 1.1.1 Cochrane 3 -- 1.1.2 Embase 5 -- 1.1.3 MEDLINE 7 -- DARE-CRD DATABASE FOR SYSTEMATIC REVIEWS 12 -- MEDLINE, EMBASE AND COCHRANE SEARCH PER INDICATION 13 -- 1.3.1 Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 13 -- 1.3.2 Dermatomyositis and Polymyositis 24 -- 1.3.3 Fetomaternal thrombocytopenia (FMAIT) 40 -- 1.3.4 Guillain-Barre 47 -- 1.3.5 Idiopathic thrombocytopenic purpura 58 -- 1.3.6 Kawasaki disease 66 -- 1.3.7 Multifocal Motor Neuropathy 75 -- 1.3.8 Myasthenia Gravis 83 -- 1.3.9 Pemphigus (Immunobullous disease) 90 -- 1.3.10 Post transfusion purpura 98 -- 1.3.11 Primary Immunodeficiency 108 -- 1.3.12 Pure red cell aplasia (Erythroblastopenia) 124 -- 1.3.13 Secondary Immunodeficiency 131 -- 1.3.14 Solid Organ Transplantation 147 -- 1.3.15 Streptococcal toxic shock syndrome 155 -- ONGOING STUDIES 166 -- ECONOMIC SEARCHES 167 -- 1.5.1 MEDLINE 167 -- 1.5.2 EconLit (via Ovid) 170 -- 1.5.3 CRD Databases – NHS EED; NHS HTA 170 -- 2 PRISMA’S PER INDICATION 171 -- 3 EXCLUSION LIST 186 -- EXCLUSION LIST OF SYSTEMATIC REVIEW WITH REASONS FOR EXCLUSION 186 -- EXCLUSION LIST OF PRIMARY STUDIES (RCTS) WITH REASONS FOR EXCLUSION 191 Link for e-copy: http://doi.org/10.57598/R327S1 Format of e-copy: PDF (2,3 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4655 Polyvalent immunoglobulins / Jolyce Bourgeois / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2019)
Polyvalent immunoglobulins : Part 1: A rapid review - SUPPLEMENT 2 [printed text] / Jolyce Bourgeois , Author ; Nicolas Fairon , Author ; Lorena San Miguel , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2019 . - 157 p. : ill., ; A4. - (KCE Reports. Health Technology Assessment (HTA); 327S2) .
ISSN : D/2019/10.273/84 : € 0,00
Languages : English (eng)
Descriptors: Indexation
2018-53-01 ; Immune System Diseases ; Immunoglobulins ; Injections, Intravenous ; R327 ; Technology Assessment, Biomedical
Classification
QW 601 ImmunoglobulinsContents note: 1 IMMUNOGLOBULINS ON THE BELGIAN MARKET 3 -- 1.1 OVERVIEW OF IMMUNOGLOBULIN PRODUCTS REGISTERED IN BELGIUM 3 -- 1.2 OVERVIEW OF STOCK RUPTURES SINCE JANUARY 2018 TILL OCTOBER 2019 4 -- 1.3 OVERVIEW OF MARKET WITHDRAWALS SINCE 2008 4 -- 2 EXTRACTION TABLES OF SYSTEMATIC REVIEWS AND RCTS 5 -- 2.1 EXTRACTION TABLE OF MODERATE TO GOOD QUALITY SRS ON SAFETY 5 -- 2.2 EXTRACTION TABLE OF MODERATE TO GOOD QUALITY SRS FOR INDICATIONS REIMBURSED IN BELGIUM 6 -- 2.3 EXTRACTION TABLE OF MODERATE TO GOOD QUALITY SR FOR INDICATIONS COMMONLY RECOGNISED IN OTHER COUNTRIES 22 -- 2.4 EXTRACTION TABLE OF INCLUDED RCTS IN SELECTED INDICATIONS 28 -- 2.5 SYSTEMATIC REVIEWS ON ‘OTHER’ INDICATIONS 49 -- 3 QUALITY ASSESSMENT 73 -- 3.1 SYSTEMATIC REVIEWS 73 -- 3.2 RISK OF BIAS OF THE RCTS 83 -- 4 EXPERT CONSULTATION 104 -- 4.1 ONLINE SURVEY 104 -- 5 ECONOMIC EVALUATION 108 -- 5.1 TEMPLATE TABLE FOR DATA EXTRACTION – ECONOMIC EVALUATIONS 108 -- 5.2 DATA EXTRACTION TABLES – ECONOMIC EVALUATIONS 110 -- 6 INTERNATIONAL COMPARISON 134 -- 6.1 BELGIUM 134 -- 6.1.1 Off-label indications in Belgium 134 -- 6.2 AUSTRALIA 135 -- 6.2.1 – The IG CRITERIA (as published on the website since January 2019) 135 -- 6.2.2 Level of evidence categories used for categorizing and establishing the Ig Criteria 141 -- 6.3 FRANCE 142 -- 6.3.1 Reimbursed indications based on licenced indications (in 2019) 142 -- 6.3.2 Priority list « Hiérarchisation des indications des immunoglobulines humaines polyvalentes – Version Avril 2019 » 143 -- 6.4 CANADA 150 -- 6.4.1 Guideline development in Canadian Provinces and Territories 150 -- 6.4.2 Recommended indications for which there is consensus in all Provincial guidelines 151 -- 6.4.3 Indications for which Provincial guidelines have no consensus 152 -- 6.4.4 Not recommended indications per Provincial Guideline 155 -- 6.5 ENGLAND 157 -- 6.5.1 Colour-coding priority system of indications for Ig use in England 157 Link for e-copy: http://doi.org/10.57598/R327S2 Format of e-copy: PDF (2,4 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4654 Polyvalent immunoglobulins / Christophe de Meester / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2020)
Polyvalent immunoglobulins : Part 2: Use in Belgium [printed text] / Christophe de Meester , Author ; Jolyce Bourgeois , Author ; Stephan Devriese , Author ; Lorena San Miguel , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2020 . - 92 p. : ill., ; A4. - (KCE Reports. Health Technology Assessment (HTA); 336) .
ISSN : D/2020/10.273/38 : € 0,00
Languages : English (eng)
Descriptors: Classification
QW 601 Immunoglobulins
Indexation
2018-52-02 ; Immunoglobulins, Intravenous ; Infusions, Subcutaneous ; R336 ; therapeutic useContents note: SCIENTIFIC REPORT 9 -- 1 INTRODUCTION 9 -- 1.1 BACKGROUND 9 -- 1.2 PROJECT SCOPE 10 -- 1.3 INTERNATIONAL CONTEXT 11 -- 1.3.1 Worldwide Ig use 11 -- 1.3.2 Plasma collection and self-sufficiency 16 -- 1.3.3 Contracting and pricing 17 -- 1.3.4 Market disruptions 18 -- 1.4 BELGIAN CONTEXT 18 -- 2 THE USE OF IMMUNOGLOBULINS IN BELGIUM 22 -- 2.1 BACKGROUND 22 -- 2.2 METHODS 22 -- 2.2.1 Overview of data sources consulted 22 -- 2.2.2 Industry Sales data 23 -- 2.2.3 Data on Reimbursed Ig 23 -- 2.2.4 Data on non-reimbursed Ig use 32 -- 2.3 RESULTS 32 -- 2.3.1 Global sales of Ig 32 -- 2.3.2 Reimbursed Ig use 33 -- 2.3.3 Public Ig expenditure in Belgium 63 -- 2.3.4 Off-label use and non-reimbursed use 66 -- 3 REQUIREMENTS FOR IG 68 -- 4 REGISTRATION IN BELGIUM 76 -- 4.1 BACKGROUND 76 -- 4.2 METHOD 76 -- 4.3 RESULTS 76 -- 5 DISCUSSION AND LIMITATIONS 79 -- REFERENCES 87 Link for e-copy: http://doi.org/10.57598/R336C Format of e-copy: PDF (2,1 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4700 Polyvalent Immunoglobulins / Christophe de Meester / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2020)
Polyvalent Immunoglobulins : Part 2: Use in Belgium – Part 2 – Supplement [printed text] / Christophe de Meester , Author ; Jolyce Bourgeois , Author ; Stephan Devriese , Author ; Lorena San Miguel , Author . - Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre, 2020 . - 42 p. : ill., ; A4. - (KCE Reports. Health Technology Assessment (HTA); 336S) .
ISSN : D/2020/10.273/39 : € 0,00
Languages : English (eng)
Descriptors: Classification
QW 601 Immunoglobulins
Indexation
2018-52-02 ; Immunoglobulins, Intravenous ; Infusions, Subcutaneous ; R336 ; therapeutic useAbstract: 1 SUPPLY PROBLEMS – MARKET 3 -- 2 QUANTITY PER PRODUCT 4 -- 3 IG EXPENDITURE 5 -- 4 QUANTITY OF IG BY HOSPITAL IN 2018 9 -- 5 PROXY INDICATIONS 10 -- 6 DOSAGE PER PATHOLOGY 15 -- 7 ONGOING CLINICAL TRIALS 19 -- 8 SURVEY TO THE HOSPTIAL PHARMACISTS 27 -- 8.1 THE QUESTIONS 27 -- 8.2 THE RESULTS 39 Link for e-copy: http://doi.org/10.57598/R336S Format of e-copy: PDF (5,1 Mb) Record link: https://kce.docressources.info/index.php?lvl=notice_display&id=4701 Polyvalente immunoglobulines / Christophe de Meester / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2020)
PermalinkPolyvalente immunoglobulines / Jolyce Bourgeois / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2019)
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PermalinkPrescrire, 350 Suppl.. Eviter les effets indésirables par Interactions médicamenteuses / Elisabeth Veyriac / Paris : Association Mieux Prescrire (2013)
PermalinkPrescrire, 362 Suppl.. Eviter les effets indésirables par Interactions médicamenteuses / Elisabeth Veyriac / Paris : Association Mieux Prescrire (2014)
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PermalinkProposals for a more effective antibiotic policy in Belgium / Roos Leroy / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2019)
PermalinkPropositions pour une politique Antibiotique plus efficace en Belgique / Roos Leroy / Brussels [Belgium] : KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre (2019)
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